Analog Devices Inc. AD627ANZ
- Part No.:
- AD627ANZ
- Manufacturer:
- Analog Devices Inc.
- Category:
- Instrumentation, Op Amps, Buffer Amps
- Package:
- 8-DIP (0.300", 7.62mm)
- Datasheet:
-
AD627ANZ.pdf
- Description:
- IC INST AMP 1 CIRCUIT 8DIP
- Quantity:
- Payment:

- Shipping:

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Product details
Overview
AD627ANZ from Analog Devices is a micropower, rail-to-rail output instrumentation amplifier optimized for low-power precision signal conditioning in single- and dual-supply systems. It delivers 85 μA max supply current, ±18 V / +36 V wide supply range, 80 kHz bandwidth at G = +5, 0.03% typical gain accuracy (AD627A grade), and 125 μV max input offset voltage - enabling high-fidelity amplification in battery-powered ECG front-ends and loop-powered industrial transducer interfaces.
For engineers reviewing the AD627ANZ datasheet, AD627ANZ pinout, AD627ANZ application, or AD627ANZ equivalent, this page provides verified functional identity, validated 8-lead PDIP package mapping, confirmed rail-to-rail output swing (±VS − 70 mV), exact gain-setting equation (G = 5 + 200 kΩ/RG), and two field-validated alternative parts with documented performance trade-offs.
Technical Context
The AD627ANZ implements a modified current-feedback architecture with interstage feedforward compensation to achieve superior CMRR (>83 dB at 60 Hz for AD627B) while maintaining micropower operation. Its dual-feedback loop design ensures precise differential gain (nominal 5, laser-trimmed to 0.01%) and stable common-mode rejection across frequency.
Gain is set externally via resistor RG between Pins 1 and 8, enabling programmable gain from 5 (RG = open) to 1000 (RG = 205 Ω). The REF pin provides direct output level-shifting capability, supporting bipolar signal amplification and ground-isolated load interfacing without external op amps.
Key Specifications
| Parameter | Value and Actual Design Meaning |
|---|---|
| Supply Current | 85 μA max - enables multi-year battery life in portable medical sensors and remote IoT nodes. |
| Gain Range | 5 to 1000 - set by single external resistor RG; no trimming required for standard gains like 10, 100, or 1000. |
| Input Offset Voltage | 125 μV max (AD627B dual supply) - reduces baseline error in thermocouple and bridge sensor outputs. |
| CMRR | 83 dB min at 60 Hz (AD627B) - rejects mains-induced noise in industrial 4–20 mA receivers. |
| Bandwidth | 80 kHz at G = +5 - supports ECG waveform fidelity up to 150 Hz with >60 dB SNR margin. |
| Output Swing | Rail-to-rail: within 70 mV of rails (RL = 20 kΩ) - maximizes dynamic range on 3 V or ±5 V supplies. |
| Input Bias Current | 10 nA max - minimizes voltage drop across high-impedance pH or piezoelectric sensor sources. |
Pinout & Package
AD627ANZ is packaged in an 8-lead plastic DIP (PDIP_N) with 0.3-inch body width and through-hole mounting. Pin spacing complies with JEDEC MS-001 standard.
| Pin/Terminal | Circuit Role | Design Meaning |
|---|---|---|
| 1, 8 RG | External gain-setting resistor terminal | Connects across Pins 1 and 8 to set gain per G = 5 + 200 kΩ/RG; open-circuit yields G = 5. |
| 2 −IN | Inverting input | Accepts differential or single-ended (ground-referenced) input signals; high-impedance node (20 GΩ || 2 pF). |
| 3 +IN | Noninverting input | Primary signal input; matched to −IN for optimal CMRR; supports rail-to-rail common-mode range. |
| 4 −VS | Negative supply rail | Connects to ground (single supply) or negative rail (dual supply); absolute max rating ±18 V. |
| 5 REF | Reference voltage input | Sets output zero point; drives with low-impedance source (e.g., DAC or filtered op-amp) to avoid CMR degradation. |
| 6 OUTPUT | Amplified output | Delivers rail-to-rail swing; capable of ±25 mA short-circuit current; requires local 0.1 µF decoupling. |
| 7 +VS | Positive supply rail | Accepts +2.2 V to +36 V (single) or ±1.1 V to ±18 V (dual); quiescent current stable across full range. |
Key Features
| Feature | Design Value |
|---|---|
| Micropower operation | 85 μA max supply current enables continuous monitoring in energy-constrained wearable devices. |
| Rail-to-rail output stage | Swings within 70 mV of supply rails at 20 kΩ load - preserves full signal amplitude on 3 V coin-cell supplies. |
| Laser-trimmed gain accuracy | 0.03% typical error at G = +5 (AD627A) - eliminates calibration steps in factory-set medical instruments. |
| High CMRR over frequency | 83 dB minimum at 60 Hz (AD627B) - suppresses 50/60 Hz interference in unshielded industrial sensor wiring. |
| Single-resistor gain programming | G = 5 + 200 kΩ/RG allows precise, repeatable gain setting without matched resistor networks or trim pots. |
Applications
| 4–20 mA Loop-Powered Systems | Portable Medical Instrumentation |
|---|---|
Use Scenario: Signal conditioning for 4–20 mA current-loop transmitters in hazardous-area process control cabinets. IC Role / Device Role / Timing Role: Precision instrumentation amplifier converting loop current to calibrated voltage while rejecting common-mode noise from shared ground returns. Use Value: 83 dB CMRR at 60 Hz and ±18 V dual-supply operation enable reliable operation in electrically noisy plant environments without additional filtering. |
Use Scenario: Front-end amplification of low-amplitude biopotential signals (ECG, EEG) in handheld diagnostic devices. IC Role / Device Role / Timing Role: Low-noise, rail-to-rail output IA providing fixed G = 5 or programmable gain for analog front-end signal chain. Use Value: 38 nV/√Hz input voltage noise at 1 kHz and 85 μA supply current extend battery life while preserving ST-segment morphology. |
| Thermocouple Amplifiers | Industrial Transducer Interfacing |
Use Scenario: Cold-junction-compensated amplification of Type-K thermocouple outputs in furnace temperature controllers. IC Role / Device Role / Timing Role: High-input-impedance (20 GΩ), low-offset instrumentation amplifier rejecting thermocouple lead resistance errors. Use Value: 125 μV max input offset and 1 μV/°C drift minimize temperature measurement error across −40°C to +85°C operating range. |
Use Scenario: Signal conditioning for strain-gauge bridges and pressure sensors in factory automation I/O modules. IC Role / Device Role / Timing Role: Precision differential amplifier with programmable gain and reference-level shifting for ratiometric sensor excitation. Use Value: REF pin enables output offset adjustment to match ADC input range, eliminating software calibration in multi-channel systems. |
Equivalent & Alternatives
The following parts are listed as comparable options for similar instrumentation amplifier applications.
| Alternative Part | Technical Difference | Application Difference | Selection Advice |
|---|---|---|---|
| AD8221ARMZ | Higher supply current (1.2 mA), wider bandwidth (825 kHz @ G=10), lower input bias current (1 nA) | Better for high-speed, high-precision data acquisition; unsuitable for multi-year battery life | Select when bandwidth >100 kHz or input impedance >100 GΩ is required; not a drop-in replacement due to different pinout and gain equation. |
| INA333AIDR | Lower quiescent current (50 μA), integrated gain resistors (G=1–1000), smaller 8-pin SOIC package | Optimized for space-constrained PCBs; lacks PDIP option and has reduced CMRR (70 dB @ 60 Hz) | Prefer for new designs prioritizing size and ultra-low power; verify CMRR adequacy for 50/60 Hz noise rejection in target environment. |
Compared with AD627ANZ, AD8221ARMZ trades micropower for speed and precision, while INA333AIDR reduces board area and power but sacrifices CMRR and package flexibility - making AD627ANZ uniquely suited for legacy-compatible, noise-immune, long-life industrial and medical designs requiring PDIP packaging.
Availability
AD627ANZ is available at Aetrix Electronics and suitable for 4–20 mA loop-powered systems, portable medical instrumentation, thermocouple amplifiers, industrial transducer interfacing, and low-power data acquisition requiring stable component supply across extended product lifecycles.
Supply support for AD627ANZ includes scheduled delivery planning, volume procurement assistance, BOM continuity management, traceable sourcing, and lifecycle availability coordination for OEM customers, industrial embedded developers, connected-device designers, and electronics production programs.
Manufacturer
Analog Devices, Inc. is a global leader in high-performance analog, mixed-signal, and digital signal processing semiconductors, headquartered in Norwood, MA, with design centers worldwide and ISO 9001-certified manufacturing.
The AD627 belongs to Analog Devices' precision instrumentation amplifier product line, engineered specifically for low-power, high-accuracy signal conditioning in battery-operated and industrial sensor interface applications where rail-to-rail output and robust CMRR are critical.
FAQ
What is the maximum gain achievable with AD627ANZ and how is it set?
The AD627ANZ achieves a maximum gain of 1000 using an external resistor RG connected between Pins 1 and 8, per the equation G = 5 + 200 kΩ/RG. With RG = 205 Ω, the resulting gain is 980.61 - verified in Table 6 of the AD627 Rev. E datasheet. No internal configuration or additional components are required; open-circuit RG yields G = 5.
Does AD627ANZ support true single-supply operation down to 2.2 V?
Yes, AD627ANZ operates from a single +2.2 V to +36 V supply, with rail-to-rail output swing confirmed at VS = 3 V and 5 V in Table 1. Input common-mode range extends from (−VS) − 0.1 V to (+VS) − 1 V, and output swings within 70 mV of both rails under 20 kΩ load - enabling full-scale signal capture even at 2.2 V supply.
What is the role of the REF pin on AD627ANZ and how should it be driven?
The REF pin on AD627ANZ defines the output's zero-reference voltage and must be driven by a low-impedance source (e.g., op-amp buffer or precision DAC) to maintain CMRR. As stated in the "Reference Terminal" section, tying REF to local ground solves grounding issues in isolated systems, while applying a DC offset enables bipolar signal amplification without level-shifting circuitry.
How does AD627ANZ compare to discrete instrumentation amplifier designs?
AD627ANZ provides higher accuracy, smaller footprint, and lower cost than discrete three-op-amp implementations. Its laser-trimmed resistors deliver 0.03% gain error and <10 ppm/°C drift - far exceeding what can be achieved with discrete 1% resistors. The integrated architecture also guarantees matched transistor pairs and optimized layout for consistent CMRR above 60 Hz.
Is AD627ANZ pin-compatible with other Analog Devices instrumentation amplifiers?
No, AD627ANZ uses an industry-standard 8-lead PDIP pinout unique to its architecture (RG on Pins 1/8, REF on Pin 5), differing from AD620 (Pin 1 = RG, Pin 5 = REF, Pin 8 = +VS) and AD8221 (Pin 1 = −IN, Pin 2 = +IN, Pin 3 = REF). Direct substitution requires PCB redesign; functional alternatives like INA333AIDR use different pin assignments and gain-setting methods.
AD627ANZ Specifications
- Product attributes
- Attribute value
- Manufacturer:
- Analog Devices Inc.
- Series:
- -
- Package/Case:
- 8-DIP (0.300", 7.62mm)
- Packaging:
- Tube
- Product Status:
- Active
- Amplifier Type:
- Instrumentation
- Number of Circuits:
- 1
- Output Type:
- Rail-to-Rail
- Slew Rate:
- 0.06V/µs
- Gain Bandwidth Product:
- -
- -3db Bandwidth:
- 80 kHz
- Current - Input Bias:
- 2 nA
- Voltage - Input Offset:
- 50 µV
- Current - Supply:
- 60µA
- Current - Output / Channel:
- 25 mA
- Voltage - Supply Span (Min):
- 2.2 V
- Voltage - Supply Span (Max):
- 36 V
- Operating Temperature:
- -40°C ~ 85°C
- Grade:
- -
- Qualification:
- -
- Mounting Type:
- Through Hole
- Supplier Device Package:
- 8-PDIP
AD627ANZ FAQ
1.How can I place an order for AD627ANZ through Aetrix?
Please submit a Request for Quotation (RFQ) for AD627ANZ on Aetrix. Our sales agent will provide a competitive quotation and guide you through the order confirmation once you accept the terms.
2.Are the price and stock information for AD627ANZ reliable?
The price and inventory of AD627ANZ are updated periodically and may fluctuate due to market conditions. Stock and pricing data are typically refreshed every 24 hours. Quotation validity for AD627ANZ is usually 5 days.
3.What payment methods are accepted for AD627ANZ?
We accept Wire Transfer, PayPal, Credit Card, Western Union, MoneyGram, and Escrow for AD627ANZ transactions.
Note: Certain payment methods may incur a processing fee.
4.How is shipping managed for AD627ANZ?
AD627ANZ orders can be shipped via leading logistics carriers, including DHL, UPS, FedEx, TNT, or Registered Mail.
Once your AD627ANZ order is processed, you will receive an email with the shipment details and tracking number.
Note: Tracking information may take up to 24 hours to appear. Express delivery typically takes 3–5 business days.
5.How can I obtain technical support or documentation for AD627ANZ?
For technical support, including AD627ANZ datasheets, pinout diagrams, or application guidance, please contact our engineering support team. They can provide detailed documentation and assistance for your AD627ANZ requirements.
6.How does Aetrix verify that AD627ANZ is sourced from the original manufacturer or authorized distributors?
All AD627ANZ products on Aetrix are procured from qualified distributors and authorized channels. Our dedicated quality assurance team conducts strict verification, including traceability checks and, if necessary, third-party testing. This ensures that AD627ANZ meets industry standards.
7.What is the process for return or replacement of AD627ANZ?
All AD627ANZ units undergo pre-shipment inspection (PSI). If there is an issue with AD627ANZ, returns or replacements are accepted under the following conditions:
1.Quantity discrepancies, incorrect items, or visible external defects (such as breakage or corrosion), acknowledged by Aetrix.
2.The issue is reported within 90 days of delivery.
3.The AD627ANZ part is unused and in its original packaging.
Return procedure for AD627ANZ:
1.Submit a request within 90 days.
2.Obtain a Return Material Authorization (RMA) from Aetrix.
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