Texas Instruments AFE4490RHAR
- Part No.:
- AFE4490RHAR
- Manufacturer:
- Texas Instruments
- Category:
- Analog Front End (AFE)
- Package:
- 40-VFQFN Exposed Pad
- Datasheet:
-
AFE4490RHAR.pdf
- Description:
- IC AFE 1 CHAN 22BIT 40VQFN
- Quantity:
- Payment:

- Shipping:

Inventory:2,814
Please send an inquiry. Send us your inquiry, and we will respond immediately.
Product details
Overview
AFE4490RHAR from Texas Instruments is a fully-integrated analog front-end IC designed for medical pulse oximeter systems, featuring dual LED drivers (LED1/LED2), two ambient-cancellation photodiode receiver channels (INP/INN), 22-bit ADC, programmable timing control, and integrated diagnostics. It delivers 110-dB dynamic range, 50 pARMS input-referred noise at 5-µA PD current, and operates from 2.0–3.6 V Rx and 3.0/5.25 V Tx supplies.
For engineers reviewing the AFE4490RHAR datasheet, AFE4490RHAR pinout, AFE4490RHAR application, or AFE4490RHAR equivalent, this device supports precise photoplethysmography (PPG) signal acquisition in wearable and clinical oximetry designs requiring ambient subtraction, fault detection, and low-noise analog signal conditioning with SPI interface control.
Technical Context
The AFE4490RHAR implements a dual-path transimpedance amplifier (TIA) architecture with independent programmable feedback R/C networks for LED1 and LED2 channels, plus selectable ambient current sources (1–10 µA) for real-time ambient cancellation. Its timing controller supports flexible pulse sequencing with LED on-times from 50 µs + settle time to 4 ms and programmable PRF up to 1200 Hz.
It integrates an 8-MHz crystal oscillator, digital ambient estimation and subtraction logic, and diagnostics for photodiode open/short, LED open/short, and cable disconnect detection. The 22-bit ADC operates with configurable sample time (50 µs–4 ms) and delivers 13.5 noise-free bits at 5-µA photodiode current.
Key Specifications
| Parameter | Value and Actual Design Meaning |
|---|---|
| ADC Resolution | 22-bit sigma-delta converter enabling high-precision PPG waveform digitization with minimal quantization error. |
| Input-Referred Noise | 50 pARMS at 5-µA photodiode current - ensures reliable detection of weak physiological signals under low-light conditions. |
| Dynamic Range | 110 dB across full LED current range - supports simultaneous capture of strong arterial pulsations and weak venous baseline without saturation or clipping. |
| LED Drive Capability | Programmable ranges: 50/75/100/150/200 mA with 8-bit resolution - enables precise optical power control for multi-wavelength oximetry. |
| Ambient Cancellation | Selectable 1–10 µA ambient current source per channel - actively subtracts ambient light interference before ADC conversion. |
| Supply Voltages | Rx supply: 2.0–3.6 V; Tx supply: 3.0 V or 5.25 V - allows independent optimization of analog receive sensitivity and LED drive headroom. |
| Operating Temperature | –40°C to +85°C - qualified for use in portable clinical devices and ruggedized wearables. |
Pinout & Package
VQFN-40 (6 mm × 6 mm) package with wettable flanks, 0.5-mm pitch, and exposed thermal pad. RoHS-compliant, moisture-sensitive level 3.
| Pin/Terminal | Circuit Role | Design Meaning |
|---|---|---|
| INP / INN | Differential photodiode inputs | Accept current from LED1/LED2 photodiodes; support ambient-cancellation TIA configuration with programmable gain and feedback. |
| TXP / TXN | H-bridge LED driver outputs | Drive external LEDs in push-pull mode with bidirectional current control up to 200 mA per channel. |
| LED_DRV_SUP | LED driver power supply | Accepts 3.0 V or 5.25 V to maximize LED forward voltage margin and optical output power. |
| RX_ANA_SUP / RX_DIG_SUP | Analog/digital supply rails | Separate 2.0–3.6 V supplies isolate noise-sensitive analog front-end from digital SPI interface circuitry. |
| SCLK / SPISOMI / SPISIMO / SPISTE | SPI interface signals | Full-duplex 4-wire SPI (mode 0, CPOL=0, CPHA=0) for register configuration and data readback at up to 20 MHz. |
| ADC_RDY / DIAG_END / LED_ALM / PD_ALM | Digital status outputs | Interrupt-capable flags indicating ADC completion, diagnostic cycle end, and LED/photodiode fault conditions. |
| AFE_PDN | Power-down control | Active-low hardware shutdown pin enabling ultra-low standby current (< 1 µA) during idle periods. |
| XIN / XOUT | Crystal oscillator terminals | Support external 8-MHz fundamental-mode crystal for low-jitter clock generation; internal oscillator eliminates need for external clock source. |
Key Features
| Feature | Design Value |
|---|---|
| Dual independent LED/ambient channels | Enables concurrent red/IR PPG acquisition with per-channel ambient subtraction-critical for SpO₂ calculation accuracy. |
| Programmable LED timing | Configurable on-time (50 µs–4 ms), off-time, and pulse repetition frequency (PRF) via SPI registers-supports adaptive power management and motion artifact reduction. |
| Integrated diagnostics | Detects photodiode open/short, LED open/short, and cable disconnect in real time-reduces system-level validation effort and improves field reliability. |
| Low-power operation | 2.3 mW total power at 3.0-V supply (including 100 µA quiescent + LED current)-extends battery life in portable oximeters. |
| Digital ambient estimation | On-chip algorithm computes ambient contribution from ambient-only samples and subtracts it digitally-eliminates need for external DSP or calibration tables. |
Applications
| Wearable Pulse Oximeters | Clinical Patient Monitors |
|---|---|
Use Scenario: Continuous SpO₂ monitoring in wrist-worn fitness trackers using red and IR LEDs with motion-tolerant signal acquisition. IC Role / Device Role / Timing Role: Analog front-end performing synchronized LED driving, ambient-cancelled photodiode current-to-voltage conversion, and 22-bit digitization of PPG waveforms. Use Value: 110-dB dynamic range and 50 pARMS noise floor enable accurate AC/DC ratio extraction even during low-perfusion conditions. | Use Scenario: Multi-parameter bedside monitors requiring FDA-grade SpO₂ accuracy with redundant sensor validation and alarm-triggered diagnostics. IC Role / Device Role / Timing Role: Primary AFE handling dual-wavelength LED excitation, ambient rejection, and fault-checked signal chain integrity verification. Use Value: Integrated LED/photodiode open-short detection and cable-off flag reduce false alarms and support automated sensor self-test routines. |
| Portable Vital Sign Sensors | Neonatal Monitoring Systems |
Use Scenario: Handheld spot-check oximeters used in home care and telehealth applications with single-button operation and rapid measurement. IC Role / Device Role / Timing Role: Complete analog signal chain including LED current control, TIA gain selection, ambient cancellation, and SPI-accessible ADC output. Use Value: Programmable LED current (50–200 mA) and on-time (50 µs–4 ms) allow optimization for skin tone variability and battery lifetime trade-offs. | Use Scenario: Low-current neonatal sensors requiring gentle optical stimulation and high-sensitivity detection of microvascular perfusion signals. IC Role / Device Role / Timing Role: Ultra-low-noise receiver channel with 13.5 noise-free bits at 5-µA PD current, supporting sub-microamp photodiode currents. Use Value: Input-referred noise of 50 pARMS ensures reliable detection of weak PPG signals from thin, highly translucent infant tissue. |
Equivalent & Alternatives
The following parts are listed as comparable options for similar analog front-end applications.
| Alternative Part | Technical Difference | Application Difference | Selection Advice |
|---|---|---|---|
| AFE4400RHA | Lower max LED drive (50 mA), narrower temp range (0°C to 70°C), no stage-2 gain option. | Limited to low-power, non-clinical applications where ambient rejection and extended temperature are not required. | Choose when cost sensitivity outweighs performance and qualification requirements. |
| AFE4403YFFR | WCSP-36 package (2.5 mm × 2.5 mm), same 100 mA LED drive, no integrated oscillator, reduced diagnostic coverage. | Targeted at space-constrained wearables where board area is critical and external clocking is acceptable. | Prefer for ultra-compact designs accepting higher layout complexity and external timing components. |
Compared with AFE4400RHA and AFE4403YFFR, the AFE4490RHAR provides broader LED current range (200 mA), full –40°C to +85°C qualification, integrated 8-MHz oscillator, and comprehensive diagnostics-making it the only option qualified for clinical-grade pulse oximetry with ambient cancellation and fault resilience.
Availability
AFE4490RHAR is available at Aetrix Electronics and suitable for wearable pulse oximeters, clinical patient monitors, and portable vital sign sensors requiring stable component supply, long-term lifecycle support, and medical-grade reliability assurance.
Supply support for AFE4490RHAR includes scheduled delivery planning, volume procurement assistance, BOM continuity management, traceable sourcing, and lifecycle availability coordination for OEM customers, industrial embedded developers, connected-device designers, and electronics production programs.
Manufacturer
Texas Instruments is a global semiconductor company specializing in analog, embedded processing, and connectivity technologies, with leadership in precision analog signal chains and medical-grade ICs.
The AFE4490RHAR belongs to TI's medical analog front-end product line, engineered specifically for photoplethysmography-based physiological sensing-prioritizing low-noise performance, ambient immunity, integrated diagnostics, and regulatory-ready design.
FAQ
What is the primary function of the AFE4490RHAR in a pulse oximeter system?
The AFE4490RHAR serves as the complete analog signal acquisition engine in pulse oximeters, performing synchronized LED driving (red and IR), ambient-cancelled photodiode current amplification, 22-bit digitization, and real-time diagnostics. Its dual-channel architecture, 110-dB dynamic range, and integrated timing controller make the AFE4490RHAR essential for extracting accurate AC/DC PPG ratios used in SpO₂ computation.
Does the AFE4490RHAR include an internal oscillator, and what is its purpose?
Yes, the AFE4490RHAR integrates an 8-MHz crystal oscillator using external XIN/XOUT pins. This oscillator provides a low-jitter clock source for the ADC, timing controller, and digital logic-eliminating the need for an external clock generator and reducing system BOM count and EMI risk. The AFE4490RHAR oscillator ensures deterministic timing for LED pulsing and ADC sampling critical to motion-robust PPG acquisition.
How does ambient light cancellation work in the AFE4490RHAR?
The AFE4490RHAR implements analog ambient cancellation by injecting a programmable 1–10 µA current into the photodiode node during ambient-only sampling phases, then digitally estimating and subtracting ambient contribution from active LED-driven samples. This dual-stage method-combining analog current injection and digital subtraction-enables robust operation under varying ambient light conditions without requiring external optical filters or mechanical shielding. The AFE4490RHAR achieves this with no additional external components.
What diagnostic capabilities does the AFE4490RHAR provide, and how are they signaled?
The AFE4490RHAR detects photodiode open/short, LED open/short, and cable disconnect conditions using internal current comparators and state-machine logic. These faults are reported via dedicated digital output pins: LED_ALM, PD_ALM, and DIAG_END. Each flag can trigger interrupts on an external MCU, enabling immediate system response-such as disabling LED drive or initiating recalibration-without polling. The AFE4490RHAR diagnostics operate autonomously during normal operation and require no host intervention.
What are the power supply requirements for the AFE4490RHAR, and why are they split?
The AFE4490RHAR requires two independent supplies: RX_ANA_SUP/RX_DIG_SUP (2.0–3.6 V) for analog and digital receiver circuitry, and LED_DRV_SUP/TX_CTRL_SUP (3.0 V or 5.25 V) for LED drivers and transmit control. This separation prevents switching noise from high-current LED pulses from coupling into the sensitive analog receive path-preserving SNR and ensuring clean PPG waveform acquisition. The AFE4490RHAR specifies < 2.3 mW total power at 3.0-V supply, including both analog and LED drive contributions.
AFE4490RHAR Specifications
- Product attributes
- Attribute value
- Manufacturer:
- Texas Instruments
- package:
- 40-VFQFN Exposed Pad
- Series:
- -
- Packaging:
- Tape & Reel (TR)
- Product Status:
- Active
- Number of Bits:
- 22
- Number of Channels:
- 1
- Power (Watts):
- -
- Voltage - Supply, Analog:
- 2V ~ 3.6V
- Voltage - Supply, Digital:
- 2V ~ 3.6V
- Mounting Type:
- Surface Mount
- Grade:
- -
- Qualification:
- -
AFE4490RHAR FAQ
1.How can I place an order for AFE4490RHAR through Aetrix?
Please submit a Request for Quotation (RFQ) for AFE4490RHAR on Aetrix. Our sales agent will provide a competitive quotation and guide you through the order confirmation once you accept the terms.
2.Are the price and stock information for AFE4490RHAR reliable?
The price and inventory of AFE4490RHAR are updated periodically and may fluctuate due to market conditions. Stock and pricing data are typically refreshed every 24 hours. Quotation validity for AFE4490RHAR is usually 5 days.
3.What payment methods are accepted for AFE4490RHAR?
We accept Wire Transfer, PayPal, Credit Card, Western Union, MoneyGram, and Escrow for AFE4490RHAR transactions.
Note: Certain payment methods may incur a processing fee.
4.How is shipping managed for AFE4490RHAR?
AFE4490RHAR orders can be shipped via leading logistics carriers, including DHL, UPS, FedEx, TNT, or Registered Mail.
Once your AFE4490RHAR order is processed, you will receive an email with the shipment details and tracking number.
Note: Tracking information may take up to 24 hours to appear. Express delivery typically takes 3–5 business days.
5.How can I obtain technical support or documentation for AFE4490RHAR?
For technical support, including AFE4490RHAR datasheets, pinout diagrams, or application guidance, please contact our engineering support team. They can provide detailed documentation and assistance for your AFE4490RHAR requirements.
6.How does Aetrix verify that AFE4490RHAR is sourced from the original manufacturer or authorized distributors?
All AFE4490RHAR products on Aetrix are procured from qualified distributors and authorized channels. Our dedicated quality assurance team conducts strict verification, including traceability checks and, if necessary, third-party testing. This ensures that AFE4490RHAR meets industry standards.
7.What is the process for return or replacement of AFE4490RHAR?
All AFE4490RHAR units undergo pre-shipment inspection (PSI). If there is an issue with AFE4490RHAR, returns or replacements are accepted under the following conditions:
1.Quantity discrepancies, incorrect items, or visible external defects (such as breakage or corrosion), acknowledged by Aetrix.
2.The issue is reported within 90 days of delivery.
3.The AFE4490RHAR part is unused and in its original packaging.
Return procedure for AFE4490RHAR:
1.Submit a request within 90 days.
2.Obtain a Return Material Authorization (RMA) from Aetrix.
AFE4490RHAR Tags

-
MCP3911A0-E/SS
Microchip Technology

-
ADS131A04IPBSR
Texas Instruments

-
ADS1292RIPBSR
Texas Instruments

-
ADS1292IRSMT
Texas Instruments

-
LMP90097MHE/NOPB
Texas Instruments

-
AD5940BCBZ-RL
Analog Devices Inc.

-
AD5940BCBZ-RL7
Analog Devices Inc.

-
AD5941BCPZ-RL7
Analog Devices Inc.

-
AD5941BCPZ
Analog Devices Inc.

-
ADS131E08IPAGR
Texas Instruments

-
LMP90100MH/NOPB
Texas Instruments

-
LMP90100MHE/NOPB
Texas Instruments
Tech Hub
A practical engineering guide to 3.3V and 5V logic compatibility, input thresholds, resistor dividers, translator ICs, MOSFET level shifting, I2C pull-ups, timing limits and power-sequencing risks.
The 74HC595 uses push-pull logic outputs, while the TPIC6B595 uses 50 V open-drain DMOS sinks for higher-power loads. This guide compares timing, current limits, 3.3 V interfacing, load wiring, thermal…
The 74HC595 converts serial data into eight stable parallel outputs. This guide covers pin functions, shift and storage timing, OE and MR behavior, drive-current limits, cascading, voltage compatibilit…
A technical comparison of level-sensitive latches and edge-triggered flip-flops, covering timing windows, setup and hold limits, master–slave operation, time borrowing, race-through, HDL inference and…
A D latch stores one bit while Enable controls when data can pass. This reference covers gate-level operation, truth tables, transparency, setup and hold timing, LE versus OE, common ICs and practical …
An SR latch stores one bit through cross-coupled feedback. This engineering reference covers NOR and NAND implementations, truth tables, forbidden-state recovery, gated operation, switch debouncing, fa…
Latch circuits retain one bit through feedback. This technical reference covers SR and D latches, truth tables, transparency, timing limits, latch-versus-flip-flop behavior, applications and common log…
An engineering guide to LED driver operation, constant-current and constant-voltage outputs, linear and switching topologies, dimming, IC selection, calculations, replacement compatibility, and fault c…
Operational amplifier guide covering op amp basics, feedback, ideal vs real op amps, common configurations, buffer circuits, offset, bias current, gain-bandwidth, slew rate, rail-to-rail limits and sel…
Jumper cables guide covering safe connection order, red and black clamp placement, final ground connection, cable gauge, length, clamp quality, copper vs CCA cables, jump starter comparison and battery…

