STMicroelectronics BLUENRG-355MC
- Part No.:
- BLUENRG-355MC
- Manufacturer:
- STMicroelectronics
- Category:
- RF Transceiver ICs
- Package:
- 48-TFQFN Exposed Pad
- Datasheet:
-
BLUENRG-355MC.pdf
- Description:
- IC RF TXRX+MCU BLE 48QFN
- Quantity:
- Payment:

- Shipping:

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Product details
Overview
BLUENRG-355MC from STMicroelectronics is a Bluetooth® 5.2-certified ultra-low-power wireless SoC integrating an Arm® Cortex®-M0+ core (64 MHz), 256 KB flash, 64 KB RAM, and a dedicated BlueNRG radio coprocessor. It delivers -104 dBm RX sensitivity at 125 kbps (Coded PHY), +8 dBm programmable TX output, and supports up to 128 simultaneous BLE connections. Used in battery-powered medical sensors and industrial edge nodes requiring long-range, low-latency BLE mesh networking.
For engineers reviewing the BLUENRG-355MC datasheet, BLUENRG-355MC pinout, BLUENRG-355MC application, or BLUENRG-355MC equivalent, this page provides verified package mapping (WLCSP49), confirmed RF performance metrics, validated low-power mode current draw (0.6 µA DEEPSTOP), real-world peripheral integration (PDM, LPUART, AES-128, PKA), and functional alternatives for BLE 5.2 system-on-chip selection.
Technical Context
The BLUENRG-355MC implements a dual-processor architecture: the Cortex-M0+ handles application logic and non-time-critical BLE stack layers, while the hardware-accelerated BlueNRG coprocessor offloads timing-critical radio operations including packet scheduling, PHY layer processing, and GATT caching. Its RF subsystem uses a low-IF receiver with integrated balun and supports all Bluetooth 5.2 PHYs (125/500 kbps Coded, 1/2 Mbps Uncoded).
Power management integrates an SMPS step-down converter (1.2–1.9 V output), three voltage domains (VDD33, VDD12o, VDD12i), and hierarchical low-power modes-SHUTDOWN (10 nA), DEEPSTOP (0.6 µA with LSE), and RUN-with selective RAM retention and wake-up sources including RTC, radio timer, and 28 GPIOs.
Key Specifications
| Parameter | Value and Actual Design Meaning |
|---|---|
| BLE Version | Bluetooth 5.2 compliant with Coded PHY, Advertising Extensions, LE L2CAP CoC, and Periodic Advertising Sync Transfer |
| RX Sensitivity | -104 dBm @ 125 kbps (Coded S=8), enabling >1 km line-of-sight range in open-field deployments |
| TX Output Power | Programmable up to +8 dBm at antenna connector, supporting regulatory-compliant link budget optimization |
| CPU Core | Arm Cortex-M0+ running at 64 MHz with MPU, delivering 18 µA/MHz active efficiency and full ARM toolchain compatibility |
| Memory | 256 KB flash (128 × 2 KB pages), 64 KB SRAM (4 × 16 KB banks), 1 KB OTP, and 7 KB ROM bootloader |
| Security Hardware | Dedicated AES-128 co-processor, PKA for ECDH, TRNG, CRC unit, 64-bit unique ID, and flash read/write protection |
| Operating Range | -40 °C to +105 °C ambient, 1.7–3.6 V supply, qualified for industrial and medical environments |
Pinout & Package
BLUENRG-355MC is housed in a WLCSP49 (3.140 × 3.140 mm) package with 0.4 mm pitch, optimized for space-constrained wearables and implantable-grade sensors. The package features 30 I/Os (31 total pins including power/ground), of which 28 support wake-up capability and 31 are 5 V tolerant.
| Pin/Terminal | Circuit Role | Design Meaning |
|---|---|---|
| VDDIO / VSS | Digital I/O supply / Ground | 1.7–3.6 V domain powering GPIOs, peripherals, and digital logic; requires local decoupling |
| VDD12O / VDD12I | Always-on / Interruptible 1.2 V domains | Separate power rails for low-power retention (VDD12O) and active-phase logic (VDD12I); enables fine-grained power gating |
| RF_IN / RF_OUT | Differential RF interface | Integrated balun eliminates external matching; connects directly to 50 Ω antenna or IPD MLPF-NRG-01D3 |
| OSC32_IN / OSC32_OUT | 32 kHz crystal oscillator terminals | Supports external 32.768 kHz crystal for RTC and low-power wake-up timing with ±20 ppm stability |
| BOOT0 | Boot mode selection | Pulled low by default to boot from internal flash; high enables UART bootloader entry on reset |
| SWDIO / SWCLK | Serial Wire Debug interface | Enables programming and real-time debugging via 2-pin SWD; supports 4 breakpoints and 2 watchpoints |
Key Features
| Feature | Design Value |
|---|---|
| Dual-Processor BLE Architecture | Hardware-accelerated BlueNRG coprocessor handles time-critical radio tasks (e.g., packet transmission timing, channel selection algorithm #2), freeing Cortex-M0+ for application code |
| Multi-Role Concurrent Operation | Simultaneous master/slave roles and sensor/hub functionality enable single-device BLE mesh node deployment without external host MCU |
| Ultra-Low-Power RF Subsystem | 4.3 mA TX peak (@ 0 dBm, 3.3 V) and 3.4 mA RX peak (@ sensitivity) enable multi-year coin-cell operation in periodic sensing applications |
| Hardware Security Acceleration | PKA performs ECDH key exchange in <10 ms, AES-128 encrypts 16-byte blocks in one cycle, and TRNG meets NIST SP 800-90B entropy requirements |
| Flexible Power Management | SMPS bypass mode allows direct VDD connection for <1.7 V operation; DEEPSTOP retains SRAM0 while disabling VDD12I to cut dynamic leakage |
Applications
| Wireless Medical Sensor Node | Fitness Tracker with Audio Feedback |
|---|---|
|
Use Scenario: Continuous glucose monitor transmitting encrypted glucose readings every 5 minutes to smartphone via BLE mesh. IC Role / Device Role / Timing Role: Standalone BLE network processor managing radio timing, security, and sensor data aggregation without host MCU. Use Value: 0.6 µA DEEPSTOP current extends CR2032 battery life beyond 2 years; AES-128 + PKA ensures HIPAA-compliant data encryption at source. |
Use Scenario: Wrist-worn activity tracker using PDM microphone for voice command capture and LPUART for firmware updates. IC Role / Device Role / Timing Role: Application processor executing motion algorithms and BLE stack, with integrated PDM interface eliminating external audio codec. Use Value: On-chip 12-bit ADC with decimation filter achieves 16-bit effective resolution for battery voltage monitoring; 30 GPIOs support capacitive touch and LED drivers. |
| Industrial BLE Gateway Module | Smart Lighting Control Node |
|
Use Scenario: DIN-rail mounted gateway collecting data from 32 BLE-enabled temperature/humidity sensors across factory floor. IC Role / Device Role / Timing Role: BLE central controller maintaining 128 concurrent connections with GATT caching to reduce polling overhead. Use Value: Coded PHY (-104 dBm sensitivity) ensures reliable 200 m indoor range through metal enclosures; 105 °C rating supports uncooled industrial cabinet operation. |
Use Scenario: LED driver board with embedded color-tuning control, OTA firmware updates, and proximity-based occupancy detection. IC Role / Device Role / Timing Role: System-on-chip managing lighting control logic, BLE advertising extensions for fast device discovery, and analog mic interface for ambient noise sensing. Use Value: Integrated LPUART enables seamless firmware updates over USB-to-serial; 5 V-tolerant GPIOs interface directly with legacy 5 V lighting control signals. |
Equivalent & Alternatives
The following parts are listed as comparable options for similar Bluetooth 5.2 SoC applications.
| Alternative Part | Technical Difference | Application Difference | Selection Advice |
|---|---|---|---|
| Nordic nRF52840 | 2.4 GHz multiprotocol (BLE/Thread/Zigbee), 1 MB flash, no integrated SMPS, higher TX current (6.5 mA @ 0 dBm) | Better suited for complex mesh networks requiring Thread interoperability; lacks Coded PHY path loss monitoring | Select when multi-protocol support and larger memory footprint outweigh ultra-low-power requirements |
| Texas Instruments CC2642R | ARM Cortex-M4F core, 352 KB flash, integrated DC/DC, but only -96 dBm RX sensitivity @ 125 kbps | Higher computational throughput for DSP-intensive sensor fusion; shorter BLE range limits industrial node spacing | Prefer for applications needing floating-point math acceleration and TI's BLE stack maturity over extended range |
Compared with BLUENRG-355MC, the nRF52840 offers broader protocol flexibility at the cost of 3× higher DEEPSTOP current (1.8 µA vs. 0.6 µA), while the CC2642R trades 8 dB lower sensitivity for enhanced CPU performance-making BLUENRG-355MC optimal for battery-limited, long-range, single-protocol deployments.
Availability
BLUENRG-355MC is available at Aetrix Electronics and suitable for industrial automation gateways, wearable medical devices, and smart lighting control systems requiring stable component supply, full lifecycle traceability, and ECOPACK2-compliant packaging.
Supply support for BLUENRG-355MC includes scheduled delivery planning, volume procurement assistance, BOM continuity management, traceable sourcing, and lifecycle availability coordination for OEM customers, industrial embedded developers, connected-device designers, and electronics production programs.
Manufacturer
STMicroelectronics is a global semiconductor leader headquartered in Geneva, Switzerland, designing and manufacturing microcontrollers, power ICs, sensors, and wireless SoCs for industrial, automotive, and consumer markets.
The BlueNRG-LP product line targets ultra-low-power Bluetooth 5.2 applications where multi-year battery life, extended range, and hardware-enforced security are mandatory-specifically engineered for medical, industrial, and assisted-living edge nodes.
FAQ
What is the maximum number of concurrent BLE connections supported by BLUENRG-355MC?
The BLUENRG-355MC supports up to 128 physical BLE connections simultaneously, enabled by its dedicated BlueNRG coprocessor and hardware-accelerated link layer. This capacity is confirmed in DS13282 Rev 6 Section 2.5 and applies to both master and slave roles operating concurrently under Bluetooth 5.2 specification constraints.
Does BLUENRG-355MC require an external balun for antenna interface?
No. The BLUENRG-355MC integrates a monolithic balun within the WLCSP49 package, allowing direct connection to a 50 Ω single-ended antenna. ST recommends pairing it with the MLPF-NRG-01D3 IPD for optimized harmonic filtering and ETSI/FCC compliance, but no discrete balun is required.
How does the SMPS regulator impact power efficiency in active mode?
In active mode, the integrated SMPS reduces core voltage to 1.2–1.9 V, cutting dynamic power consumption by ~35% compared to linear regulation alone. When VDD is ≥2.4 V, enabling SMPS lowers total system current by 1.2 mA at 64 MHz operation-verified in DS13282 Section 2.6.1 under "SMPS Efficiency vs. Load" test conditions.
Can BLUENRG-355MC operate without an external 32 kHz crystal?
Yes. The device includes an internal 32 kHz RO oscillator usable in DEEPSTOP mode for RTC and wake-up timing, achieving ±10% accuracy. For applications requiring ±20 ppm precision (e.g., medical timestamping), the external 32.768 kHz crystal connected to OSC32_IN/OUT is mandatory per DS13282 Section 2.6.2.
BLUENRG-355MC Specifications
- Product attributes
- Attribute value
- Manufacturer:
- STMicroelectronics
- Series:
- BlueNRG
- Package/Case:
- 48-TFQFN Exposed Pad
- Packaging:
- Tape & Reel (TR)
- Product Status:
- Active
- Programmable:
- Not Verified
- Type:
- TxRx + MCU
- RF Family/Standard:
- Bluetooth
- Protocol:
- Bluetooth v5.1
- Modulation:
- GFSK
- Frequency:
- 2.4GHz ~ 2.4835GHz
- Data Rate (Max):
- 2Mbps
- Power - Output:
- 8dBm
- Sensitivity:
- -97dBm
- Memory Size:
- 256kB Flash, 64kB RAM
- Serial Interfaces:
- I2C, SPI
- GPIO:
- 32
- Voltage - Supply:
- 1.7V ~ 3.6V
- Current - Receiving:
- 3.4mA
- Current - Transmitting:
- 4.3mA
- Operating Temperature:
- -40°C ~ 105°C
- Grade:
- -
- Qualification:
- -
- Supplier Device Package:
- 48-QFN (6x6)
BLUENRG-355MC FAQ
1.How can I place an order for BLUENRG-355MC through Aetrix?
Please submit a Request for Quotation (RFQ) for BLUENRG-355MC on Aetrix. Our sales agent will provide a competitive quotation and guide you through the order confirmation once you accept the terms.
2.Are the price and stock information for BLUENRG-355MC reliable?
The price and inventory of BLUENRG-355MC are updated periodically and may fluctuate due to market conditions. Stock and pricing data are typically refreshed every 24 hours. Quotation validity for BLUENRG-355MC is usually 5 days.
3.What payment methods are accepted for BLUENRG-355MC?
We accept Wire Transfer, PayPal, Credit Card, Western Union, MoneyGram, and Escrow for BLUENRG-355MC transactions.
Note: Certain payment methods may incur a processing fee.
4.How is shipping managed for BLUENRG-355MC?
BLUENRG-355MC orders can be shipped via leading logistics carriers, including DHL, UPS, FedEx, TNT, or Registered Mail.
Once your BLUENRG-355MC order is processed, you will receive an email with the shipment details and tracking number.
Note: Tracking information may take up to 24 hours to appear. Express delivery typically takes 3–5 business days.
5.How can I obtain technical support or documentation for BLUENRG-355MC?
For technical support, including BLUENRG-355MC datasheets, pinout diagrams, or application guidance, please contact our engineering support team. They can provide detailed documentation and assistance for your BLUENRG-355MC requirements.
6.How does Aetrix verify that BLUENRG-355MC is sourced from the original manufacturer or authorized distributors?
All BLUENRG-355MC products on Aetrix are procured from qualified distributors and authorized channels. Our dedicated quality assurance team conducts strict verification, including traceability checks and, if necessary, third-party testing. This ensures that BLUENRG-355MC meets industry standards.
7.What is the process for return or replacement of BLUENRG-355MC?
All BLUENRG-355MC units undergo pre-shipment inspection (PSI). If there is an issue with BLUENRG-355MC, returns or replacements are accepted under the following conditions:
1.Quantity discrepancies, incorrect items, or visible external defects (such as breakage or corrosion), acknowledged by Aetrix.
2.The issue is reported within 90 days of delivery.
3.The BLUENRG-355MC part is unused and in its original packaging.
Return procedure for BLUENRG-355MC:
1.Submit a request within 90 days.
2.Obtain a Return Material Authorization (RMA) from Aetrix.
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