Infineon Technologies CY7C65221-24LTXI
- Part No.:
- CY7C65221-24LTXI
- Manufacturer:
- Infineon Technologies
- Category:
- Controllers
- Package:
- 24-UFQFN Exposed Pad
- Datasheet:
-
CY7C65221-24LTXI.pdf
- Description:
- IC USB CNTRLR I2C/SPI/UART 24QFN
- Quantity:
- Payment:

- Shipping:

Inventory:4,622
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Product details
Overview
CY7C65221-24LTXI from Infineon is a USB 2.0 Full-Speed (12 Mbps) single-channel bridge IC supporting configurable UART (up to 3 Mbps), SPI (master up to 3 MHz / slave up to 1 MHz), and I²C (up to 400 kHz) interfaces, integrated CAPSENSE™ capacitive sensing for up to 5 buttons, battery charger detection (BCD Rev. 1.2), and 10 GPIOs - used in medical devices, POS terminals, and industrial USB-to-legacy interface adapters.
For engineers reviewing the CY7C65221-24LTXI datasheet, CY7C65221-24LTXI pinout, CY7C65221-24LTXI application, or CY7C65221-24LTXI equivalent, this device delivers verified USB-CDC/PHDC/vendor-class compatibility, on-chip 48-MHz oscillator, 512-byte configuration flash, 1.71–5.5 V operation, and -40°C to 85°C industrial temperature range with RoHS-compliant 24-pin QFN (4.0 × 4.0 mm, 0.5 mm pitch).
Technical Context
This device integrates a USB Serial Interface Engine (SIE) with embedded USB transceiver and termination resistors, enabling CDC, PHDC, and vendor-class enumeration without external components. It implements dual-clock architecture: a precision 48-MHz oscillator for USB timing and a 32-kHz oscillator for low-power suspend/resume and CAPSENSE™ auto-tuning.
The serial communication block supports simultaneous UART/I²C/SPI configuration via nonvolatile flash, with independent 256-byte TX/RX buffers per interface and hardware flow control (CTS/RTS/DTR/DSR) on UART. CAPSENSE™ operates with smart auto-tuning and links directly to five GPIOs as dedicated sensor inputs.
Key Specifications
| Parameter | Value and Actual Design Meaning |
|---|---|
| USB Speed | Full-Speed 12 Mbps - meets USB 2.0 compliance with TID 40001521; no external PHY required. |
| UART Max Data Rate | 3 Mbps - enables high-throughput legacy serial peripheral bridging (e.g., RS232/RS422). |
| SPI Clock Rate | 3 MHz master / 1 MHz slave - supports fast MCU-to-peripheral communication with Motorola/TI/National mode support. |
| I²C Speed | 400 kHz - compatible with standard/fast-mode I²C sensors and EEPROMs. |
| CAPSENSE™ Inputs | 5 dedicated buttons - auto-tuned via Infineon utility; requires no external RC network. |
| Operating Voltage | 1.71 V to 5.5 V - allows direct interfacing with 1.8 V, 3.3 V, and 5 V logic domains. |
| Temperature Range | -40°C to +85°C - qualified for industrial-grade deployment without derating. |
| ESD Rating | 2.2 kV HBM - protects USB and GPIO pins against handling-induced discharge. |
Pinout & Package
Package: 24-pin QFN (4.0 mm × 4.0 mm, 0.5 mm pitch, 0.55 mm height), RoHS-compliant, wettable flank capable.
| Pin/Terminal | Circuit Role | Design Meaning |
|---|---|---|
| VDDD | Digital supply | 1.71–5.5 V core power for digital logic and USB PHY; decoupling required. |
| VCCD | I/O supply | Configurable I/O voltage domain; sets logic levels for UART/SPI/I²C/GPIO pins. |
| USBDP / USBDM | USB differential pair | Full-Speed USB data lines with integrated 1.5 kΩ pull-up on USBDP for device enumeration. |
| nXRES | Active-low reset | Asynchronous reset input; internal pull-up; asserts on power-up and USB suspend exit. |
| GPIO[0:9] | Configurable I/O | 10 bidirectional pins; five support CAPSENSE™ sensing; all support interrupt generation. |
| VBUS | USB bus voltage sense | Monitors host-supplied 4.4–5.25 V; enables BCD detection and self/bus-powered mode selection. |
Key Features
| Feature | Design Value |
|---|---|
| Integrated 48-MHz oscillator | Eliminates external crystal; ensures USB timing accuracy and reduces BOM count by one component. |
| 512-byte flash memory | Stores VID/PID, descriptors, UART/I²C/SPI configuration, and CAPSENSE™ tuning parameters - persists across power cycles. |
| USB Battery Charging Detection (BCD) | Complies with USB BC 1.2 peripheral-side detection only; identifies DCP/CDP/SDP hosts for optimized charging path control. |
| Unique serial number per device | Fixes COM port assignment in Windows CDC mode - prevents driver re-enumeration issues in multi-device systems. |
| Multi-OS driver support | Native drivers shipped for Windows (XP–10), Linux (2.6.35+), macOS (10.6+), Android (Gingerbread+), and Windows CE. |
Applications
| Medical Device Interface | POS Terminal Adapter |
|---|---|
Use Scenario: Connecting legacy ECG or glucose meter with UART output to USB-enabled tablet or PC for data logging. IC Role / Device Role / Timing Role: USB-to-UART bridge with CDC class enumeration and fixed COM port assignment. Use Value: Eliminates need for external level shifters or crystals; CAPSENSE™ enables touch-based UI controls on the same chip. | Use Scenario: Integrating magnetic stripe reader (MSR) or barcode scanner with RS232 interface into modern USB-based retail POS system. IC Role / Device Role / Timing Role: Configurable UART bridge with RTS/CTS flow control and 3 Mbps throughput to prevent buffer overflow during burst scans. Use Value: Reduces PCB footprint vs discrete USB controller + UART + LDO solution; supports hot-plug and suspend/resume for battery backup. |
| Industrial Test Equipment | Automotive Diagnostic Tool |
Use Scenario: Bridging SPI-based sensor array (e.g., pressure/temperature) to USB host for real-time calibration and firmware update. IC Role / Device Role / Timing Role: SPI master interface with 256-byte RX/TX buffers and Motorola mode support for legacy sensor compatibility. Use Value: Enables deterministic sampling at up to 3 MHz SPI clock; 512-byte flash stores sensor-specific calibration coefficients. | Use Scenario: Enabling OBD-II scanner with I²C-connected microcontroller to communicate over USB with diagnostic software on laptop or Android tablet. IC Role / Device Role / Timing Role: I²C master bridge operating at 400 kHz with multi-master arbitration support for shared bus access. Use Value: Meets automotive -40°C to +105°C extended temp option (CY7C65211A variant); BCD detection identifies vehicle USB port type for power management. |
Equivalent & Alternatives
The following parts are listed as comparable options for similar USB-to-serial bridge applications.
| Alternative Part | Technical Difference | Application Difference | Selection Advice |
|---|---|---|---|
| CY7C65211-24LTXI | No RS485 support; different PID (0x0002 vs 0x00FB); lacks I²C/CDC mode flexibility of CY7C65211A. | Limited to UART-only legacy peripherals; not suitable for RS485 fieldbus or multi-interface coexistence. | Select when cost-sensitive design requires basic UART bridging only and avoids RS485 complexity. |
| FTDI FT232H | Single-channel USB 2.0 Hi-Speed (480 Mbps) with FIFO mode; no CAPSENSE™ or BCD; requires external crystal. | Better for high-bandwidth streaming (e.g., video capture), but adds BOM cost and layout area for crystal and load caps. | Choose when >12 Mbps throughput or parallel FIFO interface is mandatory; accept higher BoM and no integrated sensing. |
Compared with CY7C65211-24LTXI and FT232H, CY7C65221-24LTXI uniquely combines USB Full-Speed bridging, CAPSENSE™, BCD, and triple-protocol flexibility in one 4×4 mm QFN - reducing system-level component count while supporting medical, industrial, and automotive use cases requiring robust, compact, and feature-integrated connectivity.
Availability
CY7C65221-24LTXI is available at Aetrix Electronics and suitable for medical device interface, POS terminal adapter, and industrial test equipment requiring stable component supply, long-term lifecycle assurance, and RoHS-compliant packaging.
Supply support for CY7C65221-24LTXI includes scheduled delivery planning, volume procurement assistance, BOM continuity management, traceable sourcing, and lifecycle availability coordination for OEM customers, industrial embedded developers, connected-device designers, and electronics production programs.
Manufacturer
Infineon Technologies is a German semiconductor leader specializing in power management, sensing, connectivity, and security solutions for industrial, automotive, and IoT markets.
CY7C65221 belongs to Infineon's USB-Serial Bridge product line, designed to simplify USB integration into resource-constrained embedded systems by consolidating protocol translation, sensing, and power-aware USB functionality into a single chip.
FAQ
Is CY7C65221-24LTXI pin-compatible with CY7C65211-24LTXI?
Yes - both share identical 24-pin QFN (4.0 × 4.0 mm) package and pin mapping per datasheet Section 5. All signal names, power domains, and reset behavior match exactly, enabling drop-in replacement where firmware and configuration support the enhanced features of CY7C65221.
Does CY7C65221-24LTXI require an external crystal?
No - it integrates a factory-trimmed 48-MHz oscillator meeting USB Full-Speed timing requirements, eliminating external crystal, load capacitors, and associated layout constraints. The 32-kHz oscillator for low-power modes is also internal.
Can CAPSENSE™ operate independently of USB connection?
Yes - CAPSENSE™ functions autonomously using the internal 32-kHz oscillator and GPIOs configured as sensor inputs. It remains active in USB suspend mode and can generate wake-up interrupts, enabling touch-responsive sleep/wake behavior without host interaction.
What USB device classes does CY7C65221-24LTXI support out-of-the-box?
It natively supports Communication Device Class (CDC) for Virtual COM port, Personal Healthcare Device Class (PHDC) for medical telemetry, and vendor-defined class - all enabled via configuration flash; no firmware development is needed to switch between them.
CY7C65221-24LTXI Specifications
- Product attributes
- Attribute value
- Manufacturer:
- Infineon Technologies
- Package/Case:
- 24-UFQFN Exposed Pad
- Programmable:
- Not Verified
- Protocol:
- USB
- Function:
- Controller
- Interface:
- I2C, SPI, UART
- Standards:
- USB 2.0
- Voltage - Supply:
- 1.71V ~ 5.5V
- Current - Supply:
- 20mA
- Operating Temperature:
- -40°C ~ 85°C
- Supplier Device Package:
- 24-QFN (4x4)
- Grade:
- -
- Qualification:
- -
CY7C65221-24LTXI FAQ
1.How can I place an order for CY7C65221-24LTXI through Aetrix?
Please submit a Request for Quotation (RFQ) for CY7C65221-24LTXI on Aetrix. Our sales agent will provide a competitive quotation and guide you through the order confirmation once you accept the terms.
2.Are the price and stock information for CY7C65221-24LTXI reliable?
The price and inventory of CY7C65221-24LTXI are updated periodically and may fluctuate due to market conditions. Stock and pricing data are typically refreshed every 24 hours. Quotation validity for CY7C65221-24LTXI is usually 5 days.
3.What payment methods are accepted for CY7C65221-24LTXI?
We accept Wire Transfer, PayPal, Credit Card, Western Union, MoneyGram, and Escrow for CY7C65221-24LTXI transactions.
Note: Certain payment methods may incur a processing fee.
4.How is shipping managed for CY7C65221-24LTXI?
CY7C65221-24LTXI orders can be shipped via leading logistics carriers, including DHL, UPS, FedEx, TNT, or Registered Mail.
Once your CY7C65221-24LTXI order is processed, you will receive an email with the shipment details and tracking number.
Note: Tracking information may take up to 24 hours to appear. Express delivery typically takes 3–5 business days.
5.How can I obtain technical support or documentation for CY7C65221-24LTXI?
For technical support, including CY7C65221-24LTXI datasheets, pinout diagrams, or application guidance, please contact our engineering support team. They can provide detailed documentation and assistance for your CY7C65221-24LTXI requirements.
6.How does Aetrix verify that CY7C65221-24LTXI is sourced from the original manufacturer or authorized distributors?
All CY7C65221-24LTXI products on Aetrix are procured from qualified distributors and authorized channels. Our dedicated quality assurance team conducts strict verification, including traceability checks and, if necessary, third-party testing. This ensures that CY7C65221-24LTXI meets industry standards.
7.What is the process for return or replacement of CY7C65221-24LTXI?
All CY7C65221-24LTXI units undergo pre-shipment inspection (PSI). If there is an issue with CY7C65221-24LTXI, returns or replacements are accepted under the following conditions:
1.Quantity discrepancies, incorrect items, or visible external defects (such as breakage or corrosion), acknowledged by Aetrix.
2.The issue is reported within 90 days of delivery.
3.The CY7C65221-24LTXI part is unused and in its original packaging.
Return procedure for CY7C65221-24LTXI:
1.Submit a request within 90 days.
2.Obtain a Return Material Authorization (RMA) from Aetrix.
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