Infineon Technologies CY7C65221-24LTXIT
- Part No.:
- CY7C65221-24LTXIT
- Manufacturer:
- Infineon Technologies
- Category:
- Controllers
- Package:
- 24-UFQFN Exposed Pad
- Datasheet:
-
CY7C65221-24LTXIT.pdf
- Description:
- IC USB CNTRLR I2C/SPI/UART 24QFN
- Quantity:
- Payment:

- Shipping:

Inventory:4,345
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Product details
Overview
CY7C65221-24LTXIT from Infineon is a USB 2.0 Full-Speed (12 Mbps) single-channel bridge IC supporting UART, I²C, and SPI protocols with integrated CAPSENSE™ capacitive sensing, battery charger detection (BCD v1.2), and 10 GPIOs. It operates from 1.71 V to 5.5 V, features 512-byte configuration flash, 48-MHz internal oscillator, and 24-pin QFN (4.0 × 4.0 mm, 0.5 mm pitch) packaging - used in medical devices, POS terminals, and industrial USB-to-legacy interface conversion.
For engineers reviewing the CY7C65221-24LTXIT datasheet, CY7C65221-24LTXIT pinout, CY7C65221-24LTXIT application, or CY7C65221-24LTXIT equivalent, this device delivers configurable serial bridging with embedded sensing, BCD compliance, and Windows/Linux/Mac/Android driver support - critical for USB-COM port stabilization, RS232/RS485 adapter design, and touch-enabled embedded peripherals.
Technical Context
This IC integrates a USB 2.0 Serial Interface Engine (SIE) with dedicated hardware blocks for UART (up to 3 Mbps), SPI (master up to 3 MHz / slave up to 1 MHz), and I²C (up to 400 kHz), each backed by independent 256-byte TX/RX buffers. The CAPSENSE™ subsystem supports up to five self-capacitive buttons with auto-tuning via host utility.
It includes dual oscillators (48 MHz for USB/system clock; 32 kHz for low-power timing), bus/self-powered operation modes, USB suspend/wakeup capability, and BCD peripheral detection per USB BC 1.2 - enabling robust power management and legacy peripheral modernization without external crystal or charge-detection circuitry.
Key Specifications
| Parameter | Value and Actual Design Meaning |
|---|---|
| USB Speed | Full-Speed at 12 Mbps - meets USB-IF TID 40001521 certification; no external PHY required. |
| UART Max Data Rate | 3 Mbps - enables high-throughput debugging and sensor telemetry on industrial microcontrollers. |
| SPI Master Clock | Up to 3 MHz - supports fast configuration of ADCs, DACs, and display controllers. |
| I²C Speed Mode | Standard/fast mode up to 400 kHz - compatible with most sensors and EEPROMs without clock stretching. |
| CAPSENSE™ Buttons | 5 independent self-capacitive channels - allows touch UI integration without MCU firmware overhead. |
| GPIO Count | 10 programmable pins - configurable as inputs, outputs, or CAPSENSE™-linked signals. |
| Operating Voltage | 1.71 V to 5.5 V - supports direct connection to 3.3 V or 5 V logic domains and battery-backed systems. |
| ESD Rating | 2.2 kV HBM - provides baseline ESD robustness for handheld and field-deployed equipment. |
Pinout & Package
Package: 24-pin QFN (4.0 mm × 4.0 mm, 0.5 mm pitch, 0.55 mm height), RoHS-compliant, exposed thermal pad.
| Pin/Terminal | Circuit Role | Design Meaning |
|---|---|---|
| VDDD | Digital supply voltage | Core logic and USB PHY power rail (1.71–5.5 V); decoupling required near pin. |
| VBUS | USB bus voltage sense | Detects USB host presence (5 V ±10%); enables automatic bus/self-power mode selection. |
| USBDP / USBDM | USB differential data pair | Full-Speed USB 2.0 interface; integrated 1.5 kΩ pull-up on USBDP for device enumeration. |
| nXRES | Active-low reset input | Asynchronous hardware reset; driven low for ≥10 µs to force cold restart. |
| GPIO[0:9] | Configurable general-purpose I/O | Each supports digital input/output, interrupt generation, or CAPSENSE™ electrode assignment. |
| UART_TX / UART_RX | Asynchronous serial transmit/receive | Supports 2-/4-/6-pin UART configurations; flow control via RTS/CTS/DTR/DSR pins. |
| SPI_MOSI / MISO / SCLK / SS | SPI master/slave interface | Hardware-accelerated SPI with Motorola/TI/National mode support; no bit-banging required. |
| I2C_SDA / SCL | I²C bidirectional data/clock | Open-drain outputs with internal pull-ups; multi-master arbitration supported. |
Key Features
| Feature | Design Value |
|---|---|
| Integrated USB termination | On-die 1.5 kΩ pull-up on USBDP and 15 kΩ pull-downs eliminate external resistors for USB compliance. |
| Unique serial number per device | Fixes COM port assignment across reconnections - eliminates driver re-enumeration issues in field-deployed systems. |
| 512-byte flash memory | Stores VID/PID, descriptors, UART/I²C/SPI configuration, and CAPSENSE™ tuning parameters - survives power cycles. |
| Battery charging detection (BCD) | Performs D+–D− voltage comparison per USB BC 1.2 Rev. 1.2 - identifies wall chargers and enables optimized charging paths. |
| Auto-tuning CAPSENSE™ | Host-based calibration utility adjusts baseline and sensitivity dynamically - reduces false touches in varying environmental conditions. |
Applications
| Medical Device Interface | POS Terminal Peripheral Bridge |
|---|---|
Use Scenario: Connecting legacy ECG or glucose meter sensors with UART output to USB-enabled tablets or PCs. IC Role / Device Role / Timing Role: USB-to-UART bridge with fixed COM port assignment and CAPSENSE™-enabled physical button controls. Use Value: Eliminates need for external level shifters or USB controller firmware; certified drivers ensure HIPAA-compliant data logging. | Use Scenario: Integrating magnetic stripe readers or barcode scanners with RS232/RS485 interfaces into modern USB-based retail POS systems. IC Role / Device Role / Timing Role: Protocol translator with BCD-aware power management for battery-backed handheld scanners. Use Value: Enables plug-and-play USB connectivity while maintaining legacy interface timing and signal integrity. |
| Industrial Test Equipment Adapter | Gaming Accessory Controller |
Use Scenario: Converting SCPI commands from PC-based test software to GPIB-less instruments using UART or I²C. IC Role / Device Role / Timing Role: Configurable serial bridge with 256-byte I²C buffers and 400 kHz timing for synchronized sensor readouts. Use Value: Reduces latency vs. software-only USB-I²C solutions; supports multi-master arbitration during concurrent instrument access. | Use Scenario: Adding tactile touch controls and USB HID emulation to mechanical gaming keyboards or VR controllers. IC Role / Device Role / Timing Role: CAPSENSE™ + GPIO hub with USB CDC/Vendor-class firmware for custom HID report mapping. Use Value: Enables zero-latency touch response and persistent COM port binding for macro profile switching. |
Equivalent & Alternatives
The following parts are listed as comparable options for similar USB-serial bridge applications.
| Alternative Part | Technical Difference | Application Difference | Selection Advice |
|---|---|---|---|
| CY7C65211-24LTXI | No RS485 support; lacks I²C/SPI virtual COM port mode; same CAPSENSE™ and BCD capability. | Limited to UART-only bridge use cases; not suitable for I²C sensor hubs or RS485 industrial networks. | Select when only UART bridging and CAPSENSE™ are needed; lower cost than CY7C65221 variant. |
| FTDI FT232H | No CAPSENSE™ or BCD; higher USB bandwidth (Hi-Speed 480 Mbps); larger GPIO count (16) but no integrated sensing. | Preferred for high-speed data acquisition; unsuitable for touch UI or charger-aware portable designs. | Choose for raw throughput over embedded sensing; requires external charge detection circuitry if BCD needed. |
Compared with CY7C65211-24LTXI and FT232H, CY7C65221-24LTXIT uniquely combines USB-serial bridging, capacitive touch, and battery charging detection in one QFN package - simplifying BOM and PCB layout for portable, human-interface-rich embedded systems.
Availability
CY7C65221-24LTXIT is available at Aetrix Electronics and suitable for medical device interface, POS terminal peripheral bridge, and industrial test equipment adapter applications requiring stable component supply, long-term lifecycle support, and RoHS-compliant packaging.
Supply support for CY7C65221-24LTXIT includes scheduled delivery planning, volume procurement assistance, BOM continuity management, traceable sourcing, and lifecycle availability coordination for OEM customers, industrial embedded developers, connected-device designers, and electronics production programs.
Manufacturer
Infineon Technologies is a German semiconductor manufacturer specializing in power management, sensing, and connectivity solutions for automotive, industrial, and IoT markets.
CY7C65221 belongs to Infineon's EZ-USB™ FX2LP/FX3 family successor line - designed specifically for seamless USB integration into resource-constrained embedded systems with mixed-signal and human-interface requirements.
FAQ
Does CY7C65221-24LTXIT support RS485 interface?
No. CY7C65221-24LTXIT does not support RS485. That capability is exclusive to the CY7C65211A variant per Infineon's official feature comparison table. This part supports UART, I²C, and SPI only - with UART configurable for RS232/RS422 levels via external transceivers, but no native RS485 driver or polarity control.
Can the CAPSENSE™ functionality operate without a host PC?
No. CAPSENSE™ auto-tuning and calibration require Infineon's Windows-based configuration utility to compute baseline capacitance and sensitivity thresholds. The hardware detects raw capacitance changes, but adaptive filtering and button state resolution depend on host-side algorithm execution and flash parameter updates.
Is the 48-MHz oscillator sufficient for USB Full-Speed timing accuracy?
Yes. The integrated 48-MHz oscillator meets USB 2.0 Full-Speed ±0.25% tolerance requirement per specification. It is factory-trimmed and temperature-compensated, eliminating need for external crystal or oscillator - validated across 0°C to 70°C commercial grade operation.
What operating systems support the unique serial number feature?
The unique serial number feature is supported on Windows (XP through 11), Linux (kernel 2.6.35+), macOS (10.6+), and Android (Gingerbread+), provided the vendor-specific CDC driver is installed. It binds the device instance to a persistent COM/ttyACM number regardless of USB port or enumeration order.
CY7C65221-24LTXIT Specifications
- Product attributes
- Attribute value
- Manufacturer:
- Infineon Technologies
- Package/Case:
- 24-UFQFN Exposed Pad
- Programmable:
- Not Verified
- Protocol:
- USB
- Function:
- Controller
- Interface:
- I2C, SPI, UART
- Standards:
- USB 2.0
- Voltage - Supply:
- 1.71V ~ 5.5V
- Current - Supply:
- 20mA
- Operating Temperature:
- -40°C ~ 85°C
- Supplier Device Package:
- 24-QFN (4x4)
- Grade:
- -
- Qualification:
- -
CY7C65221-24LTXIT FAQ
1.How can I place an order for CY7C65221-24LTXIT through Aetrix?
Please submit a Request for Quotation (RFQ) for CY7C65221-24LTXIT on Aetrix. Our sales agent will provide a competitive quotation and guide you through the order confirmation once you accept the terms.
2.Are the price and stock information for CY7C65221-24LTXIT reliable?
The price and inventory of CY7C65221-24LTXIT are updated periodically and may fluctuate due to market conditions. Stock and pricing data are typically refreshed every 24 hours. Quotation validity for CY7C65221-24LTXIT is usually 5 days.
3.What payment methods are accepted for CY7C65221-24LTXIT?
We accept Wire Transfer, PayPal, Credit Card, Western Union, MoneyGram, and Escrow for CY7C65221-24LTXIT transactions.
Note: Certain payment methods may incur a processing fee.
4.How is shipping managed for CY7C65221-24LTXIT?
CY7C65221-24LTXIT orders can be shipped via leading logistics carriers, including DHL, UPS, FedEx, TNT, or Registered Mail.
Once your CY7C65221-24LTXIT order is processed, you will receive an email with the shipment details and tracking number.
Note: Tracking information may take up to 24 hours to appear. Express delivery typically takes 3–5 business days.
5.How can I obtain technical support or documentation for CY7C65221-24LTXIT?
For technical support, including CY7C65221-24LTXIT datasheets, pinout diagrams, or application guidance, please contact our engineering support team. They can provide detailed documentation and assistance for your CY7C65221-24LTXIT requirements.
6.How does Aetrix verify that CY7C65221-24LTXIT is sourced from the original manufacturer or authorized distributors?
All CY7C65221-24LTXIT products on Aetrix are procured from qualified distributors and authorized channels. Our dedicated quality assurance team conducts strict verification, including traceability checks and, if necessary, third-party testing. This ensures that CY7C65221-24LTXIT meets industry standards.
7.What is the process for return or replacement of CY7C65221-24LTXIT?
All CY7C65221-24LTXIT units undergo pre-shipment inspection (PSI). If there is an issue with CY7C65221-24LTXIT, returns or replacements are accepted under the following conditions:
1.Quantity discrepancies, incorrect items, or visible external defects (such as breakage or corrosion), acknowledged by Aetrix.
2.The issue is reported within 90 days of delivery.
3.The CY7C65221-24LTXIT part is unused and in its original packaging.
Return procedure for CY7C65221-24LTXIT:
1.Submit a request within 90 days.
2.Obtain a Return Material Authorization (RMA) from Aetrix.
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