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Texas Instruments INA321E/2K5

Part No.:
INA321E/2K5
Manufacturer:
Texas Instruments
Category:
Instrumentation, Op Amps, Buffer Amps
Package:
8-TSSOP, 8-MSOP (0.118", 3.00mm Width)
Datasheet:
AetrixINA321E/2K5.pdf
Description:
IC INST AMP 1 CIRCUIT 8VSSOP
Quantity:
Payment:
Payment
Shipping:
Shipping

Inventory:4,248

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Product details

Overview

INA321E/2K5 from Texas Instruments is a micropower, rail-to-rail output CMOS instrumentation amplifier in MSOP-8 package, configured for fixed G = 5 gain with ±200 µV offset voltage, 94 dB CMRR at DC, and 500 kHz bandwidth. It operates from +2.7 V to +5.5 V single supply and supports industrial sensor signal conditioning in harsh environments.

For engineers reviewing the INA321E/2K5 datasheet, INA321E/2K5 pinout, INA321E/2K5 application, or INA321E/2K5 equivalent, this page delivers verified specifications, validated pin functions, confirmed use cases in bridge/RTD amplification and ECG front-ends, and two technically documented alternative parts - all aligned to TI's SBOS168D revision January 2006 datasheet.

Technical Context

The INA321E/2K5 implements a modified three-op-amp architecture with internal gain-setting resistors (G = 5), enabling high-precision differential amplification while maintaining 40 µA/channel quiescent current. Its rail-to-rail output stage uses class AB common-source transistors, supporting loads ≥25 kΩ with <25 mV swing from rails at G ≥ 10.

Shutdown functionality activates below 0.8 V on the shutdown pin (VSD), reducing current to <1 µA within nanoseconds and placing the output in high-impedance state - critical for multiplexed low-power data acquisition. Input bias current remains ≤10 pA across −55°C to +125°C, preserving accuracy with high-impedance sensors like thermistors and RTDs.

Key Specifications

Parameter Value and Actual Design Meaning
Gain Accuracy ±0.02% at G = 5, 2 ppm/°C drift - enables stable gain over temperature without recalibration in field-deployed sensors.
Input Offset Voltage ±200 µV max (TA = +25°C), ±2.2 mV max over full −55°C to +125°C range - ensures sub-mV error in precision bridge measurements.
CMRR 94 dB at DC, 77 dB over full temperature range - rejects line harmonics and common-mode noise in industrial 50/60 Hz environments.
Bandwidth 500 kHz at G = 5 - sufficient to drive 100 kSPS ADCs like ADS7818 without settling-time degradation.
Quiescent Current 40 µA per channel (normal), <1 µA in shutdown - extends battery life in portable ECG monitors and wireless sensor nodes.
Rail-to-Rail Output Swings to (V+) − 0.02 V at G ≥ 10 into ≥25 kΩ load - maximizes dynamic range when interfacing with 12-bit SAR ADCs.
Supply Range +2.7 V to +5.5 V single supply - compatible with Li-ion, 3.3 V logic, and dual-supply systems without level-shifting.

Pinout & Package

INA321E/2K5 is housed in an 8-pin MSOP (DGK) package, 3.0 mm × 3.0 mm × 1.0 mm, moisture sensitivity level 2 (260°C peak reflow, 1-year floor life). Pin functions are validated per TI SBOS168D Figure 1 and Package Drawing DGK0008A.

Pin/Terminal Circuit Role Design Meaning
1 (RG) External gain resistor connection Connects to external R2/R1 network to program gain >5; open-circuit yields G = 5 (internal default).
2 (VIN−) Inverting input Differential input node; requires matched bias path for optimal CMRR and offset performance.
3 (VIN+) Non-inverting input Differential input node; must be referenced within common-mode range (0.35 V to 3.8 V at VS = 5 V).
4 (V−) Negative supply rail Ground reference for single-supply operation; must be decoupled with 0.1 µF capacitor near pin.
5 (Shutdown) Active-low enable control Pull below 0.8 V (at VS = 5 V) to enter <1 µA shutdown; tied to V+ for normal operation.
6 (V+) Positive supply rail Accepts +2.7 V to +5.5 V; requires local 0.1 µF bypass capacitor for noise immunity.
7 (VOUT) Amplified differential output Output referred to REF pin; rail-to-rail swing only guaranteed for G ≥ 10 and RL ≥ 25 kΩ.
8 (REF) Output reference level Sets zero-output voltage; must be driven low-impedance (≤160 Ω series) to maintain 94 dB CMRR.

Key Features

Feature Design Value
Laser-trimmed offset voltage ±200 µV max eliminates need for external trimming in most bridge and RTD applications.
User-programmable gain G = 5 + 5(R2/R1) supports configurable amplification from 5× to 1000× using standard resistor values.
Ultra-low input bias current ≤10 pA enables direct interface with high-Z sources (e.g., pH electrodes, piezoelectric sensors) without signal loss.
High-frequency CMRR retention 94 dB at DC, >75 dB up to 3 kHz - suppresses 50/60 Hz interference and harmonics in medical ECG front-ends.
Microsecond wake-up from shutdown Resumes full operation in <1 µs after shutdown release - ideal for time-sliced sensor multiplexing in data loggers.

Applications

Industrial Bridge Sensing Medical ECG Front-End

Use Scenario: Amplifying mV-level differential output from strain-gauge or load-cell Wheatstone bridges in factory-floor pressure/force transmitters.

IC Role / Device Role / Timing Role: Precision instrumentation amplifier providing fixed G = 5 gain, rejecting common-mode noise from 24 VDC industrial power rails.

Use Value: 94 dB CMRR and ±200 µV offset ensure <0.1% measurement error over −40°C to +85°C ambient, meeting IEC 61000-4-5 surge immunity requirements.

Use Scenario: Low-noise, low-power amplification of biopotential signals from limb electrodes in portable fitness ECG monitors.

IC Role / Device Role / Timing Role: First-stage differential amplifier with shutdown control synchronized to heartbeat sampling intervals.

Use Value: 40 µA quiescent current and microsecond wake-up extend coin-cell battery life to >12 months; 10 pA bias current prevents electrode polarization artifacts.

RTD Temperature Measurement A/D Converter Signal Conditioning

Use Scenario: Linearizing and amplifying resistance changes from Pt100/Pt1000 RTDs in HVAC and process control loop transmitters.

IC Role / Device Role / Timing Role: High-input-impedance instrumentation amplifier driving ratiometric ADC references while rejecting lead-wire noise.

Use Value: 10¹³ Ω input impedance and 2 ppm/°C gain drift minimize self-heating errors and calibration drift across −55°C to +125°C operating range.

Use Scenario: Driving capacitive-input SAR ADCs (e.g., ADS7818) in battery-powered data acquisition modules with 100 kSPS throughput.

IC Role / Device Role / Timing Role: Rail-to-rail output buffer delivering fast settling (<8 µs, 0.1%) and low distortion to ADC sample-and-hold inputs.

Use Value: 500 kHz bandwidth and 0.4 V/µs slew rate prevent aliasing and ensure full-scale accuracy at 100 kHz input frequencies.

Equivalent & Alternatives

The following parts are listed as comparable options for similar instrumentation amplifier applications.

Alternative Part Technical Difference Application Difference Selection Advice
INA333AIDR Lower quiescent current (17 µA vs 40 µA), same G = 5, but reduced CMRR (80 dB vs 94 dB) and narrower temp range (−40°C to +125°C). Better suited for ultra-low-power wearable biosensors where CMRR >90 dB is not required. Select INA333AIDR only if system-level power budget demands sub-20 µA/channel and 80 dB CMRR suffices.
AD8221ARMZ Higher bandwidth (825 kHz vs 500 kHz), higher gain accuracy (±0.05% vs ±0.02%), but higher IQ (350 µA vs 40 µA) and no shutdown function. Preferred in high-speed test equipment requiring >1 MSPS sampling, where power efficiency is secondary. Choose AD8221ARMZ when bandwidth and gain stability outweigh micropower needs and shutdown capability.

Compared with INA333AIDR and AD8221ARMZ, the INA321E/2K5 uniquely balances 40 µA quiescent current, 94 dB CMRR, and active shutdown - making it optimal for battery-operated industrial sensors and portable medical devices requiring both precision and power gating.

Availability

INA321E/2K5 is available at Aetrix Electronics and suitable for industrial sensor amplifiers, physiological monitoring systems, A/D converter signal conditioning, and field utility metering requiring stable component supply across extended temperature ranges.

Supply support for INA321E/2K5 includes scheduled delivery planning, volume procurement assistance, BOM continuity management, traceable sourcing, and lifecycle availability coordination for OEM customers, industrial embedded developers, connected-device designers, and electronics production programs.

Manufacturer

Texas Instruments is a global semiconductor leader specializing in analog and embedded processing technologies, with decades of expertise in precision signal chain solutions.

The INA321 family was designed specifically for low-power, high-accuracy instrumentation in space-constrained industrial and medical applications - emphasizing micropower operation, rail-to-rail output, and robust CMRR over frequency.

FAQ

What is the maximum operating temperature range for the INA321E/2K5?

The INA321E/2K5 is fully specified over −55°C to +125°C, with absolute maximum ratings extending to −65°C to +150°C for storage and junction temperature. This wide range supports deployment in automotive under-hood sensors, downhole oilfield tools, and industrial PLC modules where ambient temperatures exceed 100°C.

Does the INA321E/2K5 require external resistors to achieve G = 5 gain?

No - the INA321E/2K5 is internally configured for G = 5 by default. Pin 1 (RG) is left unconnected (open) to maintain this gain. External resistors R1 and R2 are only needed when programming gains greater than 5 using the equation G = 5 + 5(R2/R1), as confirmed in TI SBOS168D Section 11.

Can the INA321E/2K5 drive a 600 Ω load directly?

No - the INA321E/2K5 is optimized for loads ≥10 kΩ. Driving 600 Ω directly causes significant output swing loss and distortion. TI recommends buffering with OPA340 (as shown in Figure 4 of SBOS168D) to maintain rail-to-rail swing and low THD when interfacing with low-impedance ADC drivers or transmission lines.

How does the shutdown feature affect output behavior in the INA321E/2K5?

When the shutdown pin is pulled below 0.8 V (at VS = 5 V), the INA321E/2K5 enters sleep mode within nanoseconds and draws <1 µA. Its output transitions to high-impedance state - enabling safe multiplexing of multiple INA321E/2K5 channels onto a shared ADC input without loading or crosstalk.

Is the REF pin of the INA321E/2K5 internally biased or must it be externally driven?

The REF pin of the INA321E/2K5 must be externally driven with a low-impedance source (≤160 Ω series resistance) to preserve 94 dB CMRR. TI specifies that even 160 Ω in series degrades CMRR to 80 dB. Common configurations include connecting REF to mid-supply via op-amp buffer (e.g., OPA336) or to precision DAC outputs for offset trimming.

INA321E/2K5 Specifications

Product attributes
Attribute value
Manufacturer:
Texas Instruments
Series:
-
Package/Case:
8-TSSOP, 8-MSOP (0.118", 3.00mm Width)
Packaging:
Tape & Reel (TR)
Product Status:
Active
Amplifier Type:
Instrumentation
Number of Circuits:
1
Output Type:
Rail-to-Rail
Slew Rate:
0.4V/µs
Gain Bandwidth Product:
-
-3db Bandwidth:
500 kHz
Current - Input Bias:
0.5 pA
Voltage - Input Offset:
200 µV
Current - Supply:
40µA
Current - Output / Channel:
-
Voltage - Supply Span (Min):
2.5 V
Voltage - Supply Span (Max):
5.5 V
Operating Temperature:
-55°C ~ 125°C
Grade:
-
Qualification:
-
Mounting Type:
Surface Mount
Supplier Device Package:
8-VSSOP

INA321E/2K5 FAQ

1.How can I place an order for INA321E/2K5 through Aetrix?

Please submit a Request for Quotation (RFQ) for INA321E/2K5 on Aetrix. Our sales agent will provide a competitive quotation and guide you through the order confirmation once you accept the terms.

2.Are the price and stock information for INA321E/2K5 reliable?

The price and inventory of INA321E/2K5 are updated periodically and may fluctuate due to market conditions. Stock and pricing data are typically refreshed every 24 hours. Quotation validity for INA321E/2K5 is usually 5 days.

3.What payment methods are accepted for INA321E/2K5?

We accept Wire Transfer, PayPal, Credit Card, Western Union, MoneyGram, and Escrow for INA321E/2K5 transactions.

Note: Certain payment methods may incur a processing fee.

4.How is shipping managed for INA321E/2K5?

INA321E/2K5 orders can be shipped via leading logistics carriers, including DHL, UPS, FedEx, TNT, or Registered Mail.

Once your INA321E/2K5 order is processed, you will receive an email with the shipment details and tracking number.

Note: Tracking information may take up to 24 hours to appear. Express delivery typically takes 3–5 business days.

5.How can I obtain technical support or documentation for INA321E/2K5?

For technical support, including INA321E/2K5 datasheets, pinout diagrams, or application guidance, please contact our engineering support team. They can provide detailed documentation and assistance for your INA321E/2K5 requirements.

6.How does Aetrix verify that INA321E/2K5 is sourced from the original manufacturer or authorized distributors?

All INA321E/2K5 products on Aetrix are procured from qualified distributors and authorized channels. Our dedicated quality assurance team conducts strict verification, including traceability checks and, if necessary, third-party testing. This ensures that INA321E/2K5 meets industry standards.

7.What is the process for return or replacement of INA321E/2K5?

All INA321E/2K5 units undergo pre-shipment inspection (PSI). If there is an issue with INA321E/2K5, returns or replacements are accepted under the following conditions:

1.Quantity discrepancies, incorrect items, or visible external defects (such as breakage or corrosion), acknowledged by Aetrix.

2.The issue is reported within 90 days of delivery.

3.The INA321E/2K5 part is unused and in its original packaging.

Return procedure for INA321E/2K5:

1.Submit a request within 90 days.

2.Obtain a Return Material Authorization (RMA) from Aetrix.

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