STMicroelectronics NUCLEO-L452RE-P
- Part No.:
- NUCLEO-L452RE-P
- Manufacturer:
- STMicroelectronics
- Category:
- Embedded MCU, DSP Evaluation Boards
- Package:
- Datasheet:
-
NUCLEO-L452RE-P.pdf
- Description:
- NUCLEO-64 STM32L452RE EVAL BRD
- Quantity:
- Payment:

- Shipping:

Inventory:3,126
Please send an inquiry. Send us your inquiry, and we will respond immediately.
Product details
Overview
NUCLEO-L452RE-P from STMicroelectronics is a 64-pin STM32L452RET6P-based Nucleo-64 development board featuring external SMPS support, USB Micro-B–connected ST-LINK/V2-1 debugger/programmer, ARDUINO® Uno V3 and ST morpho expansion headers, and 32.768 kHz crystal oscillator - designed for ultra-low-power IoT sensor node prototyping with real-time power optimization.
For engineers reviewing the NUCLEO-L452RE-P datasheet, NUCLEO-L452RE-P pinout, NUCLEO-L452RE-P application, or NUCLEO-L452RE-P equivalent, key selection considerations include external SMPS integration capability, LQFP64 package compatibility, 512 KB Flash/160 KB RAM microcontroller resources, and ST-LINK/V2-1 debug interface with mass storage and Virtual COM port modes.
Technical Context
The NUCLEO-L452RE-P implements the STM32L452RET6P MCU - an Arm Cortex-M4 core with FPU, operating up to 80 MHz, supporting multiple low-power modes (Stop 2, Standby), and integrating 512 KB Flash, 160 KB SRAM, and hardware crypto accelerators (AES, HASH, PKA). It uses an external SMPS controller to reduce Run-mode current consumption below 80 µA/MHz.
Board-level features include dual USB connectivity (ST-LINK via Micro-B, no user USB), ARDUINO® Uno V3 and ST morpho headers exposing all MCU I/Os, one user LED shared with ARDUINO®, one user push-button and one reset button, and a 32.768 kHz crystal for RTC accuracy - enabling rapid validation of power-sensitive firmware stacks.
Key Specifications
| Parameter | Value and Actual Design Meaning |
|---|---|
| Target MCU | STM32L452RET6P - LQFP64, 512 KB Flash, 160 KB SRAM, Cortex-M4F @ 80 MHz |
| Power Architecture | External SMPS support - enables sub-80 µA/MHz Run-mode operation for battery-constrained designs |
| Debug Interface | On-board ST-LINK/V2-1 via USB Micro-B - provides mass storage programming, Virtual COM port, and SWD debugging |
| Expansion Connectors | ARDUINO® Uno V3 footprint + ST morpho headers - full access to all 51 GPIOs, analog inputs, and communication peripherals |
| Oscillators | 32.768 kHz crystal for RTC precision; no HSE installed - relies on internal 16 MHz RC or external clock source |
| Physical Form | Nucleo-64 mechanical layout (53.4 × 26.5 mm) - compatible with standard breadboard and shield stacking |
Availability
NUCLEO-L452RE-P is available at Aetrix Electronics and suitable for ultra-low-power sensor node development, portable medical device prototyping, and industrial edge-node firmware validation requiring stable component supply and long-term toolchain continuity.
Supply support for NUCLEO-L452RE-P includes scheduled delivery planning, volume procurement assistance, BOM continuity management, traceable sourcing, and lifecycle availability coordination for OEM customers, industrial embedded developers, connected-device designers, and electronics production programs.
Manufacturer
STMicroelectronics is a global semiconductor leader headquartered in Geneva, Switzerland, delivering silicon and system solutions across automotive, industrial, power, and microcontroller markets since 1987.
The STM32 Nucleo series was developed to accelerate embedded software development for Arm Cortex-M MCUs - providing standardized, open-hardware evaluation platforms with integrated debug, expandable I/O, and full STM32Cube ecosystem alignment.
FAQ
Does NUCLEO-L452RE-P support USB device functionality for the target MCU?
No. Unlike NUCLEO-L452RE (non-P variant), the NUCLEO-L452RE-P lacks a user-facing USB connector - only the ST-LINK/V2-1 debugger is exposed via USB Micro-B. The STM32L452RET6P MCU itself supports USB Device FS, but no physical USB interface circuitry is implemented on this board for end-user application use.
What distinguishes NUCLEO-L452RE-P from NUCLEO-L452RE?
The "-P" suffix indicates external SMPS support - the NUCLEO-L452RE-P includes dedicated test points and routing for connecting an external DC-DC step-down converter to supply Vcore, reducing active-mode power vs. the standard NUCLEO-L452RE which uses linear regulation only. Both share identical MCU, pinout, and debug interface.
Can I use STM32CubeIDE to program and debug NUCLEO-L452RE-P out of the box?
Yes. STM32CubeIDE natively recognizes the on-board ST-LINK/V2-1 interface. No additional drivers are required on Windows 10/11, macOS, or Linux. The board appears as a mass storage device for drag-and-drop firmware updates and as a debug probe for full SWD-based breakpointing, register inspection, and real-time variable monitoring.
Is the 32.768 kHz crystal populated and functional on NUCLEO-L452RE-P?
Yes. The 32.768 kHz crystal oscillator is fully populated and soldered on the board, directly connected to the STM32L452RET6P's LSE pins. It enables precise RTC timekeeping, calendar functions, and low-power wake-up timers - verified in the board's UM2206 user manual and schematic.
NUCLEO-L452RE-P Specifications
- Product attributes
- Attribute value
- Manufacturer:
- STMicroelectronics
- Series:
- STM32L4
- Packaging:
- Bulk
- Product Status:
- Active
- Type:
- MCU 32-Bit
- Core Processor:
- ARM® Cortex®-M4
- Platform:
- Nucleo-64
- Utilized IC / Part:
- STM32L452
- Mounting Type:
- Fixed
- Contents:
- Board(s)
NUCLEO-L452RE-P FAQ
1.How can I place an order for NUCLEO-L452RE-P through Aetrix?
Please submit a Request for Quotation (RFQ) for NUCLEO-L452RE-P on Aetrix. Our sales agent will provide a competitive quotation and guide you through the order confirmation once you accept the terms.
2.Are the price and stock information for NUCLEO-L452RE-P reliable?
The price and inventory of NUCLEO-L452RE-P are updated periodically and may fluctuate due to market conditions. Stock and pricing data are typically refreshed every 24 hours. Quotation validity for NUCLEO-L452RE-P is usually 5 days.
3.What payment methods are accepted for NUCLEO-L452RE-P?
We accept Wire Transfer, PayPal, Credit Card, Western Union, MoneyGram, and Escrow for NUCLEO-L452RE-P transactions.
Note: Certain payment methods may incur a processing fee.
4.How is shipping managed for NUCLEO-L452RE-P?
NUCLEO-L452RE-P orders can be shipped via leading logistics carriers, including DHL, UPS, FedEx, TNT, or Registered Mail.
Once your NUCLEO-L452RE-P order is processed, you will receive an email with the shipment details and tracking number.
Note: Tracking information may take up to 24 hours to appear. Express delivery typically takes 3–5 business days.
5.How can I obtain technical support or documentation for NUCLEO-L452RE-P?
For technical support, including NUCLEO-L452RE-P datasheets, pinout diagrams, or application guidance, please contact our engineering support team. They can provide detailed documentation and assistance for your NUCLEO-L452RE-P requirements.
6.How does Aetrix verify that NUCLEO-L452RE-P is sourced from the original manufacturer or authorized distributors?
All NUCLEO-L452RE-P products on Aetrix are procured from qualified distributors and authorized channels. Our dedicated quality assurance team conducts strict verification, including traceability checks and, if necessary, third-party testing. This ensures that NUCLEO-L452RE-P meets industry standards.
7.What is the process for return or replacement of NUCLEO-L452RE-P?
All NUCLEO-L452RE-P units undergo pre-shipment inspection (PSI). If there is an issue with NUCLEO-L452RE-P, returns or replacements are accepted under the following conditions:
1.Quantity discrepancies, incorrect items, or visible external defects (such as breakage or corrosion), acknowledged by Aetrix.
2.The issue is reported within 90 days of delivery.
3.The NUCLEO-L452RE-P part is unused and in its original packaging.
Return procedure for NUCLEO-L452RE-P:
1.Submit a request within 90 days.
2.Obtain a Return Material Authorization (RMA) from Aetrix.
NUCLEO-L452RE-P Tags

-
SC0915
Raspberry Pi

-
102010428
Seeed Technology Co., Ltd

-
SC0917
Raspberry Pi

-
SC1631
Raspberry Pi

-
102010328
Seeed Technology Co., Ltd

-
102010388
Seeed Technology Co., Ltd

-
4600
Adafruit Industries LLC

-
102010268
Seeed Technology Co., Ltd

-
C124
M5Stack Technology Co., Ltd.
-
3500
Adafruit Industries LLC
-
5302
Adafruit Industries LLC

-
DFR0282
DFRobot
Tech Hub
A practical engineering and sourcing framework covering lifecycle verification, lifetime-buy calculations, replacement qualification, supplier checks and counterfeit-risk controls.
TTL and CMOS logic families differ in thresholds, loading, output drive, power and timing. This engineering guide compares 74HC and 74HCT, calculates noise margins and checks 3.3 V/5 V compatibility.
A practical engineering guide to 3.3V and 5V logic compatibility, input thresholds, resistor dividers, translator ICs, MOSFET level shifting, I2C pull-ups, timing limits and power-sequencing risks.
The 74HC595 uses push-pull logic outputs, while the TPIC6B595 uses 50 V open-drain DMOS sinks for higher-power loads. This guide compares timing, current limits, 3.3 V interfacing, load wiring, thermal…
The 74HC595 converts serial data into eight stable parallel outputs. This guide covers pin functions, shift and storage timing, OE and MR behavior, drive-current limits, cascading, voltage compatibilit…
A technical comparison of level-sensitive latches and edge-triggered flip-flops, covering timing windows, setup and hold limits, master–slave operation, time borrowing, race-through, HDL inference and…
A D latch stores one bit while Enable controls when data can pass. This reference covers gate-level operation, truth tables, transparency, setup and hold timing, LE versus OE, common ICs and practical …
An SR latch stores one bit through cross-coupled feedback. This engineering reference covers NOR and NAND implementations, truth tables, forbidden-state recovery, gated operation, switch debouncing, fa…
Latch circuits retain one bit through feedback. This technical reference covers SR and D latches, truth tables, transparency, timing limits, latch-versus-flip-flop behavior, applications and common log…
An engineering guide to LED driver operation, constant-current and constant-voltage outputs, linear and switching topologies, dimming, IC selection, calculations, replacement compatibility, and fault c…

