Texas Instruments OPA4376AIPW
- Part No.:
- OPA4376AIPW
- Manufacturer:
- Texas Instruments
- Category:
- Instrumentation, Op Amps, Buffer Amps
- Package:
- 14-TSSOP (0.173", 4.40mm Width)
- Datasheet:
-
OPA4376AIPW.pdf
- Description:
- IC OPAMP GP 4 CIRCUIT 14TSSOP
- Quantity:
- Payment:

- Shipping:

Inventory:2,139
Please send an inquiry. Send us your inquiry, and we will respond immediately.
Product details
Overview
OPA4376AIPW from Texas Instruments is a quad-channel, rail-to-rail input/output precision operational amplifier with e-trim™ technology, delivering 5 µV typical offset voltage, 7.5 nV/√Hz input voltage noise at 1 kHz, and 5.5 MHz gain-bandwidth product - designed for high-accuracy signal conditioning in battery-powered medical sensors and portable instrumentation.
For engineers reviewing the OPA4376AIPW datasheet, OPA4376AIPW pinout, OPA4376AIPW application, or OPA4376AIPW equivalent, this page provides verified specifications, TSSOP-14 package mapping, real-world use cases in ADC buffering and sensor front-ends, and two validated alternative op-amps with documented functional trade-offs.
Technical Context
The OPA4376AIPW integrates four independent CMOS amplifiers on a single die, each featuring e-trim™ trimming for ultra-low dc error and stable performance across –40°C to +125°C. Its rail-to-rail input stage supports common-mode voltages from (V–) – 0.1 V to (V+) + 0.1 V, while the rail-to-rail output delivers ±20 mV swing from supply rails at 10 kΩ load.
Each amplifier operates from 2.2 V to 5.5 V single supply, draws only 760 µA typical quiescent current per channel, and achieves 90 dB minimum CMRR and 120 dB open-loop gain - enabling high-precision closed-loop configurations without external trimming or calibration.
Key Specifications
| Parameter | Value and Actual Design Meaning |
|---|---|
| Offset Voltage | 5 µV typical - enables sub-16-bit error floor in precision DC-coupled gain stages without nulling circuitry |
| Input Voltage Noise | 7.5 nV/√Hz at 1 kHz - preserves SNR in low-level sensor interfaces (e.g., thermopile, strain gauge) |
| Gain Bandwidth Product | 5.5 MHz - supports stable unity-gain buffering of 100-kSPS+ SAR ADCs with <2 µs settling to 0.01% |
| Supply Voltage Range | 2.2 V to 5.5 V - allows direct operation from single Li-ion or dual alkaline cells without LDO regulation |
| Quiescent Current | 760 µA per amplifier - enables four-channel precision amplification within 3.1 mA total system budget |
| Input Bias Current | 0.2 pA typical - minimizes voltage error across high-impedance sources (>100 MΩ) |
| CMRR | 90 dB minimum - rejects >30 mV of common-mode interference in unshielded industrial sensor nodes |
Pinout & Package
TSSOP-14 package (5.00 mm × 4.40 mm body), thermally optimized for PCB heat dissipation with RθJA = 107.8 °C/W and RθJB = 52.6 °C/W - suitable for compact, convection-cooled layouts in handheld test equipment.
| Pin/Terminal | Circuit Role | Design Meaning |
|---|---|---|
| 1, 7, 8, 14 | OUT A/B/C/D | Amplifier output terminals - rail-to-rail swing supports full-scale ADC input drive without level-shifting |
| 2, 6, 9, 13 | –IN A/B/C/D | Inverting inputs - matched to +IN pins for balanced differential gain accuracy |
| 3, 5, 10, 12 | +IN A/B/C/D | Non-inverting inputs - accept signals down to (V–) – 0.1 V, enabling true single-supply sensor biasing |
| 4 | V+ | Positive supply rail - accepts 2.2 V to 5.5 V; PSRR ≥ 90 dB ensures immunity to noisy digital supply coupling |
| 11 | V– | Negative supply rail - typically ground in single-supply systems; supports split-rail operation to ±2.75 V |
Key Features
| Feature | Design Value |
|---|---|
| e-trim™ DC precision | 25 µV max offset and 0.32 µV/°C drift over –40°C to +125°C - eliminates factory calibration in production test |
| Rail-to-rail I/O | Input extends 100 mV beyond rails; output swings within 20 mV of rails at 10 kΩ - maximizes dynamic range in 3.3 V systems |
| Low-noise architecture | 0.8 µVPP (0.1–10 Hz) + 7.5 nV/√Hz (1 kHz) - meets ENOB >16.5 bits for 16-bit ADC drivers |
| Capacitive load drive | Stable with up to 250 pF in unity-gain buffer configuration - simplifies anti-aliasing filter integration |
| ESD robustness | ±4000 V HBM, ±1000 V CDM - withstands handling in non-ESD-controlled assembly environments |
Applications
| ADC Buffer | Medical Instrumentation |
|---|---|
Use Scenario: Driving the analog input of a 16-bit SAR ADC (e.g., ADS8327) in a portable ECG monitor. IC Role / Device Role / Timing Role: Precision voltage follower with 0.01% settling in <2 µs, rejecting power-supply ripple before digitization. Use Value: Maintains >94 dB SNR by contributing only 0.8 µVPP low-frequency noise and 7.5 nV/√Hz broadband noise. |
Use Scenario: Amplifying microvolt-level biopotential signals from dry-electrode EEG sensors. IC Role / Device Role / Timing Role: Low-bias, low-noise first-stage amplifier with rail-to-rail input enabling zero-volt-referenced electrode biasing. Use Value: 0.2 pA input bias avoids electrode polarization errors; 5 µV offset prevents baseline drift in DC-coupled acquisition. |
| Handheld Test Equipment | Active Filtering |
Use Scenario: Signal conditioning front-end in a battery-powered multimeter measuring µV-level thermocouple outputs. IC Role / Device Role / Timing Role: High-impedance, low-drift gain stage with 2.2–5.5 V supply flexibility for Li-ion operation. Use Value: 760 µA per channel enables four-channel simultaneous measurement within 3.1 mA total current budget. |
Use Scenario: Second-order Butterworth anti-aliasing filter (50 kHz cutoff) preceding a 500 kSPS ADC in data loggers. IC Role / Device Role / Timing Role: Unity-gain stable active filter amplifier with 5.5 MHz GBW ensuring flat passband response. Use Value: Drives 250 pF capacitive loads directly - eliminates need for isolation resistors that degrade THD+N performance. |
Equivalent & Alternatives
The following parts are listed as comparable options for similar precision operational amplifier applications.
| Alternative Part | Technical Difference | Application Difference | Selection Advice |
|---|---|---|---|
| OPA4188AIPW | Zero-drift architecture; 0.03 µV/°C drift vs. OPA4376AIPW's 0.32 µV/°C; higher 1.2 mA IQ | Better long-term dc stability in oven-controlled lab instruments; less suitable for ultra-low-power portable designs | Choose OPA4188AIPW when drift-critical DC accuracy outweighs battery life constraints |
| AD8604ARUZ | Higher 12 nV/√Hz noise; 500 µV max offset; 500 µA IQ; same TSSOP-14 footprint | Adequate for 12–14-bit systems; lower cost where sub-16-bit ENOB is acceptable | Choose AD8604ARUZ for cost-sensitive, moderate-precision applications with relaxed noise requirements |
Compared with OPA4376AIPW, OPA4188AIPW trades 57% higher quiescent current for 10× lower drift, while AD8604ARUZ reduces cost and power but sacrifices 100× higher offset and 60% more noise - making OPA4376AIPW optimal for battery-powered 16-bit precision systems requiring best-in-class noise/power balance.
Availability
OPA4376AIPW is available at Aetrix Electronics and suitable for medical instrumentation, handheld test equipment, and precision ADC buffering requiring stable component supply across extended temperature ranges and long production lifecycles.
Supply support for OPA4376AIPW includes scheduled delivery planning, volume procurement assistance, BOM continuity management, traceable sourcing, and lifecycle availability coordination for OEM customers, industrial embedded developers, connected-device designers, and electronics production programs.
Manufacturer
Texas Instruments is a global semiconductor leader specializing in analog and embedded processing technologies, with decades of expertise in precision op-amp design and manufacturing.
The OPAx376 family was engineered for high-accuracy, low-power signal conditioning in portable and battery-operated systems - emphasizing e-trim™-enabled dc precision, rail-to-rail operation, and wide supply flexibility without sacrificing ac performance.
FAQ
What is the maximum operating temperature for the OPA4376AIPW?
The OPA4376AIPW is specified for continuous operation from –40°C to +125°C ambient temperature, with absolute maximum junction temperature rated at 150°C. Thermal metrics confirm RθJA = 107.8 °C/W in TSSOP-14, enabling reliable performance in sealed enclosures with natural convection cooling. The OPA4376AIPW maintains full electrical specifications across this full industrial temperature range.
Does the OPA4376AIPW support single-supply operation?
Yes, the OPA4376AIPW fully supports single-supply operation from 2.2 V to 5.5 V. Its rail-to-rail input stage accepts common-mode voltages from (V–) – 0.1 V to (V+) + 0.1 V, and its rail-to-rail output swings within 20 mV of both supply rails under 10 kΩ load - enabling true single-supply signal chain design without level-shifting components. The OPA4376AIPW is commonly used with 3.3 V or 5 V rails in portable instrumentation.
What is the input bias current specification for the OPA4376AIPW?
The OPA4376AIPW features an ultra-low input bias current of 0.2 pA typical and ≤10 pA maximum at 25°C, enabled by its CMOS input stage. This value remains below 100 pA across the full –40°C to +125°C operating range, as confirmed in TI's Typical Characteristics plots. Such low bias current prevents significant voltage error when interfacing with high-impedance sensors like photodiodes or pH electrodes - a key advantage of the OPA4376AIPW over bipolar-input alternatives.
Can the OPA4376AIPW drive capacitive loads without oscillation?
Yes, the OPA4376AIPW is unity-gain stable and can directly drive up to 250 pF of pure capacitive load in buffer configuration, as verified in Figure 16 of the SBOS406G datasheet. For loads exceeding 250 pF, a small series resistor (10–20 Ω) between output and capacitor restores phase margin without degrading dc accuracy. This capability makes the OPA4376AIPW suitable for driving ADC input capacitance and integrated anti-aliasing filters without external compensation networks.
Is the OPA4376AIPW pin-compatible with other quad op-amps in TSSOP-14?
No, the OPA4376AIPW has a unique pinout optimized for signal integrity and thermal performance in quad configuration - specifically: OUT A (pin 1), –IN A (pin 2), +IN A (pin 3), V+ (pin 4), +IN B (pin 5), –IN B (pin 6), OUT B (pin 7), OUT C (pin 8), –IN C (pin 9), +IN C (pin 10), V– (pin 11), +IN D (pin 12), –IN D (pin 13), OUT D (pin 14). It is not pin-compatible with generic quad op-amps like LM324 or TL074, and requires dedicated PCB layout per TI's recommended footprint.
OPA4376AIPW Specifications
- Product attributes
- Attribute value
- Manufacturer:
- Texas Instruments
- Series:
- -
- Package/Case:
- 14-TSSOP (0.173", 4.40mm Width)
- Packaging:
- Tube
- Product Status:
- Active
- Amplifier Type:
- General Purpose
- Number of Circuits:
- 4
- Output Type:
- Single Ended, Rail-to-Rail
- Slew Rate:
- 2V/µs
- Gain Bandwidth Product:
- 5.5 MHz
- -3db Bandwidth:
- -
- Current - Input Bias:
- 0.2 pA
- Voltage - Input Offset:
- 5 µV
- Current - Supply:
- 760µA (x4 Channels)
- Current - Output / Channel:
- 50 mA
- Voltage - Supply Span (Min):
- 2.2 V
- Voltage - Supply Span (Max):
- 5.5 V
- Operating Temperature:
- -40°C ~ 125°C
- Grade:
- -
- Qualification:
- -
- Mounting Type:
- Surface Mount
- Supplier Device Package:
- 14-TSSOP
OPA4376AIPW FAQ
1.How can I place an order for OPA4376AIPW through Aetrix?
Please submit a Request for Quotation (RFQ) for OPA4376AIPW on Aetrix. Our sales agent will provide a competitive quotation and guide you through the order confirmation once you accept the terms.
2.Are the price and stock information for OPA4376AIPW reliable?
The price and inventory of OPA4376AIPW are updated periodically and may fluctuate due to market conditions. Stock and pricing data are typically refreshed every 24 hours. Quotation validity for OPA4376AIPW is usually 5 days.
3.What payment methods are accepted for OPA4376AIPW?
We accept Wire Transfer, PayPal, Credit Card, Western Union, MoneyGram, and Escrow for OPA4376AIPW transactions.
Note: Certain payment methods may incur a processing fee.
4.How is shipping managed for OPA4376AIPW?
OPA4376AIPW orders can be shipped via leading logistics carriers, including DHL, UPS, FedEx, TNT, or Registered Mail.
Once your OPA4376AIPW order is processed, you will receive an email with the shipment details and tracking number.
Note: Tracking information may take up to 24 hours to appear. Express delivery typically takes 3–5 business days.
5.How can I obtain technical support or documentation for OPA4376AIPW?
For technical support, including OPA4376AIPW datasheets, pinout diagrams, or application guidance, please contact our engineering support team. They can provide detailed documentation and assistance for your OPA4376AIPW requirements.
6.How does Aetrix verify that OPA4376AIPW is sourced from the original manufacturer or authorized distributors?
All OPA4376AIPW products on Aetrix are procured from qualified distributors and authorized channels. Our dedicated quality assurance team conducts strict verification, including traceability checks and, if necessary, third-party testing. This ensures that OPA4376AIPW meets industry standards.
7.What is the process for return or replacement of OPA4376AIPW?
All OPA4376AIPW units undergo pre-shipment inspection (PSI). If there is an issue with OPA4376AIPW, returns or replacements are accepted under the following conditions:
1.Quantity discrepancies, incorrect items, or visible external defects (such as breakage or corrosion), acknowledged by Aetrix.
2.The issue is reported within 90 days of delivery.
3.The OPA4376AIPW part is unused and in its original packaging.
Return procedure for OPA4376AIPW:
1.Submit a request within 90 days.
2.Obtain a Return Material Authorization (RMA) from Aetrix.
OPA4376AIPW Tags

-
LM358DT
STMicroelectronics

-
LM358DR
Texas Instruments

-
LM2904DR
Texas Instruments

-
LM358ADR
Texas Instruments
-
LM2904DGKR
Texas Instruments
-
LM324DR
Texas Instruments

-
MCP6006T-E/OT
Microchip Technology

-
MCP6006UT-E/OT
Microchip Technology

-
LM324PWR
Texas Instruments

-
LM2902PWR
Texas Instruments
-
LM2902DR
Texas Instruments

-
LM358P
Texas Instruments
Tech Hub
A practical engineering guide to 3.3V and 5V logic compatibility, input thresholds, resistor dividers, translator ICs, MOSFET level shifting, I2C pull-ups, timing limits and power-sequencing risks.
The 74HC595 uses push-pull logic outputs, while the TPIC6B595 uses 50 V open-drain DMOS sinks for higher-power loads. This guide compares timing, current limits, 3.3 V interfacing, load wiring, thermal…
The 74HC595 converts serial data into eight stable parallel outputs. This guide covers pin functions, shift and storage timing, OE and MR behavior, drive-current limits, cascading, voltage compatibilit…
A technical comparison of level-sensitive latches and edge-triggered flip-flops, covering timing windows, setup and hold limits, master–slave operation, time borrowing, race-through, HDL inference and…
A D latch stores one bit while Enable controls when data can pass. This reference covers gate-level operation, truth tables, transparency, setup and hold timing, LE versus OE, common ICs and practical …
An SR latch stores one bit through cross-coupled feedback. This engineering reference covers NOR and NAND implementations, truth tables, forbidden-state recovery, gated operation, switch debouncing, fa…
Latch circuits retain one bit through feedback. This technical reference covers SR and D latches, truth tables, transparency, timing limits, latch-versus-flip-flop behavior, applications and common log…
An engineering guide to LED driver operation, constant-current and constant-voltage outputs, linear and switching topologies, dimming, IC selection, calculations, replacement compatibility, and fault c…
Operational amplifier guide covering op amp basics, feedback, ideal vs real op amps, common configurations, buffer circuits, offset, bias current, gain-bandwidth, slew rate, rail-to-rail limits and sel…
Jumper cables guide covering safe connection order, red and black clamp placement, final ground connection, cable gauge, length, clamp quality, copper vs CCA cables, jump starter comparison and battery…
