NXP Semiconductors SC16IS752IPW-S
- Part No.:
- SC16IS752IPW-S
- Manufacturer:
- NXP Semiconductors
- Category:
- Controllers
- Package:
- 28-TSSOP (0.173", 4.40mm Width)
- Datasheet:
-
SC16IS752IPW-S.pdf
- Description:
- IC UART DUAL I2C/SPI 28-TSSOP
- Quantity:
- Payment:

- Shipping:

Inventory:3,048
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Product details
Overview
SC16IS752IPW-S from NXP Semiconductors is a dual-channel UART IC with I²C/SPI interface, 64-byte TX/RX FIFOs, IrDA SIR support up to 115.2 kbit/s, and 8 programmable GPIOs - used in battery-powered industrial gateways for protocol bridging between microcontrollers and RS-232/RS-485 peripherals.
For engineers reviewing the SC16IS752IPW-S datasheet, SC16IS752IPW-S pinout, SC16IS752IPW-S application, or SC16IS752IPW-S equivalent, key selection considerations include I²C vs. SPI interface configuration, Auto-RTS/CTS hardware flow control implementation, IrDA SIR compatibility at 115.2 kbit/s, and TSSOP28 package integration into space-constrained PCB layouts.
Technical Context
The SC16IS752IPW-S implements two independent 16C450-compatible UART channels with fully programmable framing (5–8 data bits, 1–2 stop bits, parity options), integrated baud rate generator supporting up to 5 Mbit/s in 16× clock mode, and bidirectional I²C-bus (Fast-mode, 400 kbit/s) or SPI (Mode 0, 4 Mbit/s max) host interface.
It integrates automatic RS-485 direction control via RTS signal, internal loopback mode for diagnostics, sleep current <30 μA at 3.3 V, and interrupt prioritization across seven levels including RX FIFO timeout, Xoff detection, and modem status change - all managed through register sets backward compatible with legacy 16C450 software stacks.
Key Specifications
| Parameter | Value and Actual Design Meaning |
|---|---|
| UART Channels | Dual independent full-duplex UARTs with separate TX/RX/RTS/CTS pins per channel |
| FIFO Depth | 64 bytes transmit and receive FIFO per channel - reduces host CPU interrupt load and enables burst data handling |
| Max Data Rate | 5 Mbit/s in 16× clock mode - supports high-speed serial links such as industrial Ethernet converters |
| Interface Options | I²C-bus (400 kbit/s Fast-mode) or SPI (Mode 0, 4 Mbit/s) - selected by I2C/SPI pin logic level |
| IrDA Support | Built-in IrDA SIR encoder/decoder up to 115.2 kbit/s - enables infrared communication without external transceiver |
| GPIO Pins | 8 programmable I/O pins - configurable as general-purpose I/O or modem control signals (DSR/DTR/RI/CD) |
| Supply Voltage | 2.5 V or 3.3 V operation with 5 V tolerant inputs - simplifies level-shifting in mixed-voltage systems |
| Operating Temp | −40 °C to +95 °C industrial range - validated for factory automation and outdoor embedded deployments |
Pinout & Package
TSSOP28 package (SOT361-1), 4.4 mm body width, lead pitch 0.65 mm - optimized for compact, hand-held, and battery-operated designs.
| Pin/Terminal | Circuit Role | Design Meaning |
|---|---|---|
| RTSA / RTSB | UART request-to-send output (active LOW) | Controls data transmission readiness per channel; enables Auto-RTS flow control when EFR[6] = 1 |
| CTSA / CTSB | UART clear-to-send input (active LOW) | Signals modem readiness; enables Auto-CTS flow control when EFR[7] = 1 |
| TXA / TXB | UART transmitter output | Drives RS-232/RS-485 line drivers; supports automatic RS-485 direction control via RTS |
| RXA / RXB | UART receiver input | Accepts TTL-level serial data; disabled during internal loopback mode |
| IRQ | Open-drain interrupt output (active LOW) | Signals 7 prioritized interrupt sources including RX FIFO timeout, Xoff detection, and modem status change |
| I2C/SPI | Interface select input | Logic HIGH = I²C mode; logic LOW = SPI mode - determines function of SDA/SO/SCLK/SCL pins |
| GPIO0–GPIO7 | Programmable I/O or modem control | Configurable via IOControl register; supports DSR/DTR/RI/CD functions or general digital I/O |
| RESET | Hardware reset input (active LOW) | Synchronously resets internal registers except DLL/DLH/XON1/XON2/XOFF1/XOFF2 |
Key Features
| Feature | Design Value |
|---|---|
| Auto hardware flow control | Independent Auto-RTS and Auto-CTS per UART channel - eliminates RX FIFO overrun without host polling |
| Software flow control | Programmable Xon/Xoff characters (single/dual) with configurable comparison logic - enables robust protocol handshaking |
| RS-485 driver control | Automatic direction control via RTS output with polarity inversion option - removes need for external direction logic |
| Backward register compatibility | Fully compatible with 16C450 register map - allows reuse of existing UART driver code and OS porting effort |
| Sleep mode | Current <30 μA at 3.3 V when EFR[4] and IER[4] enabled - extends battery life in portable telemetry devices |
| Interrupt prioritization | Seven-level priority scheme with dedicated Xoff, modem status, and I/O change interrupts - ensures timely response to critical events |
Applications
| Industrial Serial Gateway | Portable Diagnostic Tool |
|---|---|
|
Use Scenario: Protocol translation between ARM-based PLC controller (I²C) and legacy RS-485 field devices. IC Role / Device Role / Timing Role: Dual UART bridges host processor to two independent serial buses while managing flow control and RS-485 direction automatically. Use Value: Eliminates need for discrete level shifters and direction controllers; 64-byte FIFOs absorb burst traffic from motor drives without packet loss. |
Use Scenario: Handheld maintenance tool connecting via Bluetooth MCU (SPI) to test HVAC control panels with RS-232 debug ports. IC Role / Device Role / Timing Role: SPI-to-serial bridge with low-power sleep mode activated between diagnostic sessions. Use Value: 30 μA sleep current extends single-charge battery life beyond 12 months; IrDA SIR enables quick firmware updates via infrared. |
| Factory Automation Node | Cellular Data Terminal |
|
Use Scenario: Edge node aggregating sensor data over RS-485 Modbus and forwarding via cellular module (I²C-connected). IC Role / Device Role / Timing Role: Dual UART handles concurrent Modbus RTU and AT command channel communication with independent FIFO management. Use Value: Auto-RTS/CTS prevents buffer overflow during high-throughput sensor logging; 8 GPIOs monitor door switches and power faults. |
Use Scenario: Embedded telematics unit using SPI-connected MCU to manage GPS (UART A) and LTE modem (UART B) simultaneously. IC Role / Device Role / Timing Role: Central UART hub enabling full-duplex GPS NMEA and LTE AT command exchange with hardware flow control. Use Value: Independent TX/RX FIFO trigger levels prevent command collision; 5 V tolerant inputs simplify interface to legacy GPS modules. |
Equivalent & Alternatives
The following parts are listed as comparable options for similar dual UART with I²C/SPI interface applications.
| Alternative Part | Technical Difference | Application Difference | Selection Advice |
|---|---|---|---|
| SC16IS752IBS | HVQFN32 package (5 × 5 mm), thermal pad, 32-pin layout - differs only in footprint and thermal performance | Preferred for high-density PCBs requiring better thermal dissipation and smaller board area | Select SC16IS752IBS when board space or thermal management outweighs TSSOP28 rework familiarity. |
| SC16IS762IPW | Supports SPI clock up to 15 Mbit/s and IrDA SIR up to 1.152 Mbit/s - otherwise identical register set and pinout | Required only when higher SPI throughput or faster IrDA is needed; not drop-in compatible for IrDA speed | Choose SC16IS762IPW only if system demands >4 Mbit/s SPI or 1.152 Mbit/s IrDA - otherwise SC16IS752IPW-S suffices. |
Compared with SC16IS752IBS, the SC16IS752IPW-S offers easier hand-soldering and legacy TSSOP rework compatibility; compared with SC16IS762IPW, it provides identical functionality at lower cost and reduced IrDA speed - making it optimal for standard industrial serial bridging where 115.2 kbit/s IrDA and 4 Mbit/s SPI are sufficient.
Availability
SC16IS752IPW-S is available at Aetrix Electronics and suitable for factory automation, portable diagnostic tools, and cellular data terminals requiring stable component supply and long-term industrial-grade availability.
Supply support for SC16IS752IPW-S includes scheduled delivery planning, volume procurement assistance, BOM continuity management, traceable sourcing, and lifecycle availability coordination for OEM customers, industrial embedded developers, connected-device designers, and electronics production programs.
Manufacturer
NXP Semiconductors is a global semiconductor company headquartered in Eindhoven, Netherlands, specializing in secure connectivity solutions for automotive, industrial, and IoT markets.
The SC16IS752IPW-S belongs to NXP's serial interface bridge product line, designed specifically to simplify microcontroller expansion with reliable, low-power, multi-protocol UART interfaces for resource-constrained embedded systems.
FAQ
What interface modes does the SC16IS752IPW-S support?
The SC16IS752IPW-S supports both I²C-bus (Fast-mode, up to 400 kbit/s) and SPI (Mode 0, up to 4 Mbit/s) host interfaces. Interface selection is controlled by the logic level on the I2C/SPI pin: HIGH selects I²C, LOW selects SPI. Pin functions like SDA, SO, SCLK, and SCL are dynamically reassigned based on this setting, and the device operates exclusively in target (slave) mode for both protocols.
Does the SC16IS752IPW-S support automatic RS-485 direction control?
Yes, the SC16IS752IPW-S provides automatic RS-485 driver direction control via its RTS output signal. When enabled, the RTS pin toggles automatically to assert driver enable before transmission and de-assert after completion. It also supports RTS polarity inversion via register configuration, allowing direct connection to common RS-485 transceivers without external logic.
What is the maximum IrDA SIR speed supported by the SC16IS752IPW-S?
The SC16IS752IPW-S supports IrDA SIR at up to 115.2 kbit/s. This is a fixed capability of the SC16IS752 variant; the SC16IS762 variant supports 1.152 Mbit/s, but that higher speed is not available on the SC16IS752IPW-S. The built-in encoder/decoder eliminates the need for external IrDA PHY components.
How many programmable GPIOs does the SC16IS752IPW-S provide?
The SC16IS752IPW-S provides eight programmable GPIO pins (GPIO0–GPIO7), each configurable either as general-purpose digital I/O or as modem control signals (DSR/DTR/RI/CD) via the IOControl register. These pins support interrupt-on-change and can be individually assigned input/output direction and pull-up/pull-down states.
Is the SC16IS752IPW-S register-compatible with legacy UARTs?
Yes, the SC16IS752IPW-S features a register set fully backward compatible with the industry-standard 16C450 UART. This includes identical memory-mapped address offsets for THR/RHR, IER, FCR, LCR, LSR, MSR, and MCR registers - enabling direct porting of existing driver software and reducing firmware development time for migration projects.
SC16IS752IPW-S Specifications
- Product attributes
- Attribute value
- Manufacturer:
- NXP Semiconductors
- Package/Case:
- 28-TSSOP (0.173", 4.40mm Width)
- Programmable:
- Not Verified
- Protocol:
- RS232, RS485
- Function:
- Controller
- Interface:
- I2C, SPI, UART
- Standards:
- -
- Voltage - Supply:
- 2.5V, 3.3V
- Current - Supply:
- 2mA
- Operating Temperature:
- -40°C ~ 95°C
- Supplier Device Package:
- 28-TSSOP
- Grade:
- -
- Qualification:
- -
SC16IS752IPW-S FAQ
1.How can I place an order for SC16IS752IPW-S through Aetrix?
Please submit a Request for Quotation (RFQ) for SC16IS752IPW-S on Aetrix. Our sales agent will provide a competitive quotation and guide you through the order confirmation once you accept the terms.
2.Are the price and stock information for SC16IS752IPW-S reliable?
The price and inventory of SC16IS752IPW-S are updated periodically and may fluctuate due to market conditions. Stock and pricing data are typically refreshed every 24 hours. Quotation validity for SC16IS752IPW-S is usually 5 days.
3.What payment methods are accepted for SC16IS752IPW-S?
We accept Wire Transfer, PayPal, Credit Card, Western Union, MoneyGram, and Escrow for SC16IS752IPW-S transactions.
Note: Certain payment methods may incur a processing fee.
4.How is shipping managed for SC16IS752IPW-S?
SC16IS752IPW-S orders can be shipped via leading logistics carriers, including DHL, UPS, FedEx, TNT, or Registered Mail.
Once your SC16IS752IPW-S order is processed, you will receive an email with the shipment details and tracking number.
Note: Tracking information may take up to 24 hours to appear. Express delivery typically takes 3–5 business days.
5.How can I obtain technical support or documentation for SC16IS752IPW-S?
For technical support, including SC16IS752IPW-S datasheets, pinout diagrams, or application guidance, please contact our engineering support team. They can provide detailed documentation and assistance for your SC16IS752IPW-S requirements.
6.How does Aetrix verify that SC16IS752IPW-S is sourced from the original manufacturer or authorized distributors?
All SC16IS752IPW-S products on Aetrix are procured from qualified distributors and authorized channels. Our dedicated quality assurance team conducts strict verification, including traceability checks and, if necessary, third-party testing. This ensures that SC16IS752IPW-S meets industry standards.
7.What is the process for return or replacement of SC16IS752IPW-S?
All SC16IS752IPW-S units undergo pre-shipment inspection (PSI). If there is an issue with SC16IS752IPW-S, returns or replacements are accepted under the following conditions:
1.Quantity discrepancies, incorrect items, or visible external defects (such as breakage or corrosion), acknowledged by Aetrix.
2.The issue is reported within 90 days of delivery.
3.The SC16IS752IPW-S part is unused and in its original packaging.
Return procedure for SC16IS752IPW-S:
1.Submit a request within 90 days.
2.Obtain a Return Material Authorization (RMA) from Aetrix.
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