STMicroelectronics STM32L451REI6
- Part No.:
- STM32L451REI6
- Manufacturer:
- STMicroelectronics
- Category:
- Microcontrollers
- Package:
- 64-UFBGA
- Datasheet:
-
STM32L451REI6.pdf
- Description:
- IC MCU 32BIT 512KB FLASH 64UFBGA
- Quantity:
- Payment:

- Shipping:

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Product details
Overview
STM32L451REI6 from STMicroelectronics is an ultra-low-power Arm® Cortex®-M4 32-bit MCU with FPU, operating up to 80 MHz (100 DMIPS), featuring 512 KB Flash, 160 KB SRAM, and integrated analog peripherals including 12-bit ADC (5 Msps), dual 12-bit DACs, op-amp with PGA, and RTC with hardware calendar-designed for battery-powered IoT sensor nodes requiring long runtime and audio-capable edge processing.
For engineers reviewing the STM32L451REI6 datasheet, STM32L451REI6 pinout, STM32L451REI6 application, or STM32L451REI6 equivalent, key selection criteria include its 22 nA shutdown current, LPUART wake-up capability in Stop 2 mode, SAI audio interface, and UFBGA64 (5×5 mm) package with 64 I/Os-critical for space-constrained wearable and smart meter designs.
Technical Context
The STM32L451REI6 implements FlexPowerControl architecture with seven low-power modes, including Stop 2 (2.05 µA) and Shutdown (22 nA), enabled by dual voltage regulators and autonomous peripheral clock gating. Its ART Accelerator™ eliminates Flash wait states at 80 MHz, while the interconnect matrix decouples bus arbitration between CPU, DMA, and peripherals.
It integrates a full audio subsystem: SAI interface supporting I²S/PCM, two 12-bit DACs with sample-and-hold, and an op-amp with programmable gain amplifier-enabling direct analog output without external signal conditioning. The 12-bit ADC supports hardware oversampling up to 16-bit resolution and operates at 200 µA/Msps for energy-efficient sensing.
Key Specifications
| Parameter | Value and Actual Design Meaning |
|---|---|
| CPU Core | Arm Cortex-M4 with FPU and DSP instructions, 100 DMIPS @ 80 MHz-enables real-time sensor fusion and lightweight ML inference. |
| Memory | 512 KB Flash (single-bank, code readout protection), 160 KB SRAM (32 KB with parity)-supports secure firmware updates and robust data logging. |
| Low-Power Performance | 22 nA Shutdown mode (5 wakeup pins), 2.05 µA Stop 2 mode-extends coin-cell battery life to >10 years in periodic-sensing applications. |
| Analog Peripherals | 1× 12-bit ADC (5 Msps, 16-bit oversampling), 2× 12-bit DACs, 1× op-amp with PGA, 2× comparators-replaces discrete signal chain components. |
| Audio Interface | 1× SAI (serial audio interface) supporting I²S/PCM, plus LPUART with Stop 2 wake-up-enables always-on voice trigger and low-latency audio streaming. |
| Package & I/O | UFBGA64 (5×5 mm, 0.4 mm pitch), 64 I/Os (most 5 V-tolerant)-fits compact PCB layouts while maintaining compatibility with legacy 5 V peripherals. |
| Clock System | Dual PLLs (system + audio), MSI auto-trimmed by LSE (±0.25%), HSI48 with CRS-ensures precise timing for USB and audio without external crystals. |
Pinout & Package
STM32L451REI6 uses the UFBGA64 (5×5 mm, 0.4 mm pitch) package, optimized for high-density portable designs. Pin count is 64, with 57 general-purpose I/Os (most 5 V-tolerant), dedicated debug (SWD), reset, VDD/VSS rails, and analog supply pins (VREF+, VREF–, VBAT).
| Pin/Terminal | Circuit Role | Design Meaning |
|---|---|---|
| VDD, VSS | Main power supply and ground | Core logic supply (1.71–3.6 V); separate VDDA/VSSA required for analog accuracy. |
| PA0–PA15, PB0–PB15, PC0–PC15, PD2, PE0–PE15 | General-purpose I/Os | 64-pin mapping includes 57 GPIOs; most support 5 V tolerance, enabling mixed-voltage system interfacing. |
| PA2, PA3, PA4, PA5, PA6, PA7, PB10, PB11 | SAI interface signals | Support I²S master/slave, MCLK, FS, SCK, SD lines-direct connection to MEMS microphones or audio codecs. |
| PA4, PA5 | DAC outputs | DAC1_OUT1 / DAC2_OUT1; each with internal sample-and-hold-drives analog sensors or audio amplifiers without external buffering. |
| PA1, PA4, PA5, PB0, PB1 | Wakeup pins | Five dedicated pins capable of waking from Shutdown/Standby-enables event-driven low-power operation. |
| PA13, PA14 | SWD debug interface | SWDIO/SWCLK pins; no JTAG required-reduces debug footprint and simplifies production programming. |
Key Features
| Feature | Design Value |
|---|---|
| FlexPowerControl architecture | Seven configurable low-power modes with sub-µA shutdown and 4 µs wake-up-enables duty-cycled operation in energy harvesting systems. |
| ART Accelerator™ | Zero-wait-state execution from Flash at 80 MHz-eliminates performance penalty of embedded Flash, matching SRAM speed. |
| Integrated analog front-end | ADC + DAC + op-amp + comparators + VREFBUF on single die-reduces BOM count and PCB area vs. discrete signal chain. |
| SAI + LPUART combo | Simultaneous audio streaming and ultra-low-power UART wake-up-supports always-listening voice interfaces with <2.5 µA background current. |
| True random number generator | Cryptographically secure entropy source compliant with NIST SP800-90B-enables TLS handshake and secure boot without external TRNG. |
Applications
| Smart Wearable Sensor Hub | Industrial Wireless Node |
|---|---|
Use Scenario: Continuous ECG/PPG monitoring in wrist-worn device powered by CR2032 battery. IC Role / Device Role / Timing Role: Primary MCU managing sensor acquisition (ADC), analog front-end (op-amp, DAC), RTC-triggered sampling, and BLE packet formatting via USART. Use Value: 22 nA Shutdown and 2.05 µA Stop 2 enable multi-year battery life; SAI supports onboard audio feedback without external codec. | Use Scenario: Battery-operated vibration/temperature node in predictive maintenance system, transmitting data every 15 minutes via LoRaWAN. IC Role / Device Role / Timing Role: Sensor aggregator with 12-bit ADC oversampling, CRC-protected data logging to Flash, and LPUART wake-up for scheduled transmission. Use Value: 106 nA Standby with RTC ensures precise interval timing; 5 V-tolerant I/Os interface directly with legacy industrial transducers. |
| Smart Meter Audio Alert | Portable Medical Diagnostic Tool |
Use Scenario: Ultrasonic flow meter with audible leak-detection tone generation and tamper alert. IC Role / Device Role / Timing Role: Real-time audio waveform synthesis using SAI and dual DACs, coupled with capacitive touch sensing (TSC) for UI control. Use Value: Integrated op-amp drives piezo buzzer directly; 375 nA Standby with RTC maintains calendar and alarm state during mains-off periods. | Use Scenario: Handheld blood glucose analyzer requiring calibrated analog measurement and Bluetooth LE reporting. IC Role / Device Role / Timing Role: Precision analog acquisition (ADC + VREFBUF + temperature sensor), secure firmware update (Flash ROP), and SWD-based field calibration. Use Value: 2.5 V buffered reference ensures ±0.2% ADC accuracy; 96-bit unique ID enables per-unit calibration traceability. |
Equivalent & Alternatives
The following parts are listed as comparable options for similar ultra-low-power MCU applications.
| Alternative Part | Technical Difference | Application Difference | Selection Advice |
|---|---|---|---|
| STM32L432KCU6 | Smaller memory (256 KB Flash, 64 KB SRAM), no SAI, no DAC, 48-pin UFQFPN package | Lacks audio capability and analog output; suited for pure sensing/control without local audio feedback | Select when cost and size are critical and audio/analog output is unnecessary. |
| STM32L552RET6 | ARMv8-M TrustZone®, 512 KB Flash, 256 KB SRAM, same UFBGA64, but 3.6 V max supply and higher active current | Added security features and higher performance, but 3.2 µA Stop 2 vs. 2.05 µA-less optimal for extreme battery life | Select when secure boot, encrypted storage, or PSA Level 2 certification is required. |
Compared with STM32L432KCU6, the STM32L451REI6 adds SAI, dual DACs, and op-amp for self-contained audio/sensing; versus STM32L552RET6, it trades TrustZone security for lower static current-making it superior for multi-year battery applications where security is handled externally.
Availability
STM32L451REI6 is available at Aetrix Electronics and suitable for smart wearables, industrial wireless sensors, smart metering, and portable medical devices requiring stable component supply across extended product lifecycles.
Supply support for STM32L451REI6 includes scheduled delivery planning, volume procurement assistance, BOM continuity management, traceable sourcing, and lifecycle availability coordination for OEM customers, industrial embedded developers, connected-device designers, and electronics production programs.
Manufacturer
STMicroelectronics is a global semiconductor leader headquartered in Geneva, specializing in microcontrollers, power management, and analog/mixed-signal ICs for industrial, automotive, and consumer markets.
The STM32L4 series targets ultra-low-power embedded applications demanding high performance-per-microwatt, with design focus on battery longevity, integrated analog, and secure firmware execution in constrained environments.
FAQ
What is the maximum operating frequency and core type of the STM32L451REI6?
The STM32L451REI6 features an Arm Cortex-M4 core with FPU, running at up to 80 MHz with 100 DMIPS performance. It uses the Adaptive Real-Time Accelerator (ART Accelerator™) to achieve zero-wait-state execution from Flash memory, ensuring deterministic timing for real-time tasks without SRAM-only code placement.
Does the STM32L451REI6 support USB connectivity?
No, the STM32L451REI6 does not include a USB peripheral. It lacks USB PHY and controller hardware. For USB-enabled variants in the same family, consider the STM32L452xx or STM32L476xx series, which integrate USB 2.0 FS controllers and crystal-less USB clock recovery.
What are the supported low-power modes and their typical current consumption?
The STM32L451REI6 supports seven low-power modes: Shutdown (22 nA), Standby (106 nA), Standby with RTC (375 nA), Stop 2 (2.05 µA), Stop 1 (3.4 µA), Sleep (84 µA/MHz), and Run (84 µA/MHz). Current values are measured at 3.3 V, 25 °C, with ART Accelerator enabled and Flash execution.
Is the STM32L451REI6 pin-compatible with other STM32L4x1 packages?
Yes, the STM32L451REI6 in UFBGA64 is pin-compatible with other STM32L451xx variants in the same package (e.g., STM32L451CEI6), sharing identical pin functions and electrical characteristics. However, it is not pin-compatible with LQFP64 or UFBGA100 variants due to differing pin counts and layout.
STM32L451REI6 Specifications
- Product attributes
- Attribute value
- Manufacturer:
- STMicroelectronics
- Package/Case:
- 64-UFBGA
- Series:
- STM32L4
- Packaging:
- Tray
- Product Status:
- Active
- Programmable:
- Not Verified
- Core Processor:
- ARM® Cortex®-M4
- Core Size:
- 32-Bit Single-Core
- Speed:
- 80MHz
- Connectivity:
- CANbus, I2C, IrDA, LINbus, MMC/SD, QSPI, SAI, SPI, UART/USART
- Peripherals:
- Brown-out Detect/Reset, DMA, PWM, WDT
- Number of I/O:
- 52
- Program Memory Size:
- 512KB (512K x 8)
- Program Memory Type:
- FLASH
- EEPROM Size:
- -
- RAM Size:
- 160K x 8
- Voltage - Supply (Vcc/Vdd):
- 1.71V ~ 3.6V
- Data Converters:
- A/D 16x12b; D/A 1x12b
- Oscillator Type:
- Internal
- Operating Temperature:
- -40°C ~ 85°C (TA)
- Grade:
- -
- Qualification:
- -
- Mounting Type:
- Surface Mount
- Supplier Device Package:
STM32L451REI6 FAQ
1.How can I place an order for STM32L451REI6 through Aetrix?
Please submit a Request for Quotation (RFQ) for STM32L451REI6 on Aetrix. Our sales agent will provide a competitive quotation and guide you through the order confirmation once you accept the terms.
2.Are the price and stock information for STM32L451REI6 reliable?
The price and inventory of STM32L451REI6 are updated periodically and may fluctuate due to market conditions. Stock and pricing data are typically refreshed every 24 hours. Quotation validity for STM32L451REI6 is usually 5 days.
3.What payment methods are accepted for STM32L451REI6?
We accept Wire Transfer, PayPal, Credit Card, Western Union, MoneyGram, and Escrow for STM32L451REI6 transactions.
Note: Certain payment methods may incur a processing fee.
4.How is shipping managed for STM32L451REI6?
STM32L451REI6 orders can be shipped via leading logistics carriers, including DHL, UPS, FedEx, TNT, or Registered Mail.
Once your STM32L451REI6 order is processed, you will receive an email with the shipment details and tracking number.
Note: Tracking information may take up to 24 hours to appear. Express delivery typically takes 3–5 business days.
5.How can I obtain technical support or documentation for STM32L451REI6?
For technical support, including STM32L451REI6 datasheets, pinout diagrams, or application guidance, please contact our engineering support team. They can provide detailed documentation and assistance for your STM32L451REI6 requirements.
6.How does Aetrix verify that STM32L451REI6 is sourced from the original manufacturer or authorized distributors?
All STM32L451REI6 products on Aetrix are procured from qualified distributors and authorized channels. Our dedicated quality assurance team conducts strict verification, including traceability checks and, if necessary, third-party testing. This ensures that STM32L451REI6 meets industry standards.
7.What is the process for return or replacement of STM32L451REI6?
All STM32L451REI6 units undergo pre-shipment inspection (PSI). If there is an issue with STM32L451REI6, returns or replacements are accepted under the following conditions:
1.Quantity discrepancies, incorrect items, or visible external defects (such as breakage or corrosion), acknowledged by Aetrix.
2.The issue is reported within 90 days of delivery.
3.The STM32L451REI6 part is unused and in its original packaging.
Return procedure for STM32L451REI6:
1.Submit a request within 90 days.
2.Obtain a Return Material Authorization (RMA) from Aetrix.
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