STMicroelectronics STM32L452CEU3
- Part No.:
- STM32L452CEU3
- Manufacturer:
- STMicroelectronics
- Category:
- Microcontrollers
- Package:
- 48-UFQFN Exposed Pad
- Datasheet:
-
STM32L452CEU3.pdf
- Description:
- IC MCU 32BIT 512KB FLSH 48UFQFPN
- Quantity:
- Payment:

- Shipping:

Inventory:794
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Product details
Overview
STM32L452CEU3 from STMicroelectronics is an ultra-low-power Arm® Cortex®-M4 32-bit MCU with FPU, operating up to 80 MHz (100 DMIPS), featuring 512 KB Flash, 160 KB SRAM, and integrated analog peripherals including 12-bit ADC (5 Msps), dual 12-bit DAC, and operational amplifier. It supports external SMPS for 36 µA/MHz run efficiency and targets battery-powered IoT sensors and portable medical devices requiring RTC, capacitive touch, and USB full-speed connectivity.
For engineers reviewing the STM32L452CEU3 datasheet, STM32L452CEU3 pinout, STM32L452CEU3 application, or STM32L452CEU3 equivalent, key selection criteria include verified ultra-low-power modes (22 nA shutdown, 375 nA standby with RTC), FlexPowerControl architecture, ART Accelerator™ for zero-wait-state Flash execution, and UFBGA64 (5×5 mm) package compatibility with space-constrained designs.
Technical Context
The STM32L452CEU3 implements an Adaptive Real-Time Accelerator (ART Accelerator™) that enables deterministic 0-wait-state execution from Flash memory at 80 MHz, eliminating instruction cache misses in real-time control loops. Its FlexPowerControl architecture integrates dual voltage regulators (LDO and external SMPS support) and eight low-power modes-including Stop 2 (2.40 µA with RTC) and Shutdown (22 nA)-with 4 µs wakeup latency.
It features a dedicated interconnect matrix enabling concurrent peripheral access without bus contention, and includes hardware-accelerated cryptographic primitives (CRC, RNG) alongside a 96-bit unique ID. The analog subsystem operates on an independent supply rail, supporting simultaneous high-precision sensing (12-bit ADC + hardware oversampling) and low-noise signal conditioning (OPAMP with PGA, dual comparators, VREFBUF).
Key Specifications
| Parameter | Value and Actual Design Meaning |
|---|---|
| CPU Core | Arm Cortex-M4 with FPU, 80 MHz max frequency, 100 DMIPS performance - enables real-time DSP and sensor fusion without external co-processors. |
| Memory | 512 KB Flash (single-bank, code readout protection), 160 KB SRAM (32 KB with hardware parity) - supports secure firmware updates and robust data logging in safety-critical applications. |
| Power Efficiency | 36 µA/MHz in SMPS-run mode @3.3 V - reduces battery drain in always-on edge nodes; 22 nA shutdown current enables multi-year operation on coin cells. |
| Analog Peripherals | 1×12-bit ADC (5 Msps, 16-bit oversampling), 2×12-bit DAC, 1×OPAMP with PGA, 2×ultra-low-power comparators - enables closed-loop analog control and precision sensor interface without external signal chain ICs. |
| Connectivity | USB 2.0 full-speed (crystal-less), 4×I²C FM+, 3×USART, LPUART, SAI, CAN 2.0B, SDMMC - supports wired and wireless gateway functions with audio, industrial fieldbus, and memory expansion capability. |
| Package & Pin Count | UFBGA64 (5×5 mm, 0.5 mm pitch), 64-pin ball grid array - provides compact footprint for wearables and implantable-grade PCB layouts with thermal and EMI advantages over QFP. |
| Operating Range | -40 °C to +125 °C ambient temperature, 1.71–3.6 V supply - qualified for automotive cabin modules, industrial motor controllers, and outdoor environmental monitoring. |
Pinout & Package
STM32L452CEU3 is housed in a 5×5 mm UFBGA64 package with 0.5 mm ball pitch, optimized for high-density PCB routing and thermal dissipation in compact battery-powered systems. Pin functions are validated per STMicroelectronics datasheet DS11912 Rev 7, Section 4 ("Pinouts and pin description").
| Pin/Terminal | Circuit Role | Design Meaning |
|---|---|---|
| VDD, VSS | Main power supply and ground | Dual-supply domain: VDD powers digital core and I/Os; separate VDDA/VSSA required for analog peripherals to ensure noise isolation in mixed-signal operation. |
| PA0–PA15, PB0–PB15, PC0–PC15, PD0–PD15, PE0–PE15 | General-purpose I/Os | Up to 83 fast I/Os (most 5 V-tolerant); support 16 alternate functions per pin including USART, SPI, I²C, USB, CAN - enables flexible peripheral mapping without board redesign. |
| NRST | Active-low reset input | Asynchronous reset pin with internal pull-up; accepts external push-button or supervisor IC assertion - ensures reliable cold-start and brown-out recovery. |
| BOOT0 | Boot mode selection | High at power-up selects system memory bootloader; used for factory programming or firmware recovery via UART/USB without debug probe. |
| VBAT | Backup power supply | Supplies RTC and 32×32-bit backup registers during main power loss - enables calendar continuity and tamper-protected state retention in energy-harvesting systems. |
| OSC_IN / OSC_OUT | External crystal oscillator interface | Supports 4–48 MHz HSE crystal for precise system clock; optional 32.768 kHz LSE for RTC calibration - critical for time-sensitive protocols like LIN or USB suspend/resume timing. |
Key Features
| Feature | Design Value |
|---|---|
| FlexPowerControl architecture | Eight configurable low-power modes (Shutdown, Standby, Stop 2, etc.) with sub-µA quiescent currents and <4 µs wakeup - extends battery life in intermittent-sensing applications such as smart meters and asset trackers. |
| ART Accelerator™ | Zero-wait-state execution from Flash at 80 MHz - eliminates CPU stalls during interrupt-driven control tasks (e.g., motor commutation, PWM generation) without requiring external SRAM. |
| Capacitive Sensing Controller (TSC) | 21-channel hardware-accelerated touch sensing - supports touchkey, linear, and rotary sensors with built-in noise immunity, reducing firmware overhead in HMI designs. |
| Independent Analog Supply (VDDA) | Dedicated 1.62–3.6 V analog rail decoupled from digital VDD - prevents switching noise from corrupting ADC/DAC conversions in precision measurement systems. |
| Batch Acquisition Mode (BAM) | Peripheral-triggered low-power data capture without CPU intervention - enables continuous sensor sampling during Stop mode, ideal for vibration monitoring or environmental logging. |
Applications
| Wearable Health Monitor | Smart Utility Meter |
|---|---|
Use Scenario: Continuous ECG/PPG signal acquisition with Bluetooth LE telemetry and onboard battery management. IC Role / Device Role / Timing Role: Main controller executing sensor fusion algorithms, managing USB/SAI audio output, and maintaining RTC-based data timestamping. Use Value: 375 nA Standby-with-RTC and 2.40 µA Stop 2 mode enable >5-year operation on CR2032; integrated OPAMP and 12-bit ADC eliminate discrete front-end components. |
Use Scenario: Electricity/water/gas meter with anti-tampering, pulse counting, and NB-IoT backhaul communication. IC Role / Device Role / Timing Role: System-on-chip handling metrology calculations, secure firmware updates, and LPUART/NB-IoT modem interfacing. Use Value: Hardware CRC and RNG support AES-128 encryption for DLMS/COSEM compliance; -40 °C to +125 °C rating ensures reliability in outdoor meter enclosures. |
| Industrial Motor Drive Sensor Node | Portable Medical Diagnostic Device |
Use Scenario: Compact BLDC motor controller with Hall-effect feedback, thermal monitoring, and CAN bus diagnostics. IC Role / Device Role / Timing Role: Real-time motion control unit running FOC algorithms, driving gate drivers via TIM1 advanced timers, and communicating via CAN 2.0B. Use Value: 100 DMIPS + FPU handles vector math for field-oriented control; 16-bit timer resolution and 4 µs wakeup ensure precise PWM dead-time management. |
Use Scenario: Handheld ultrasound or point-of-care blood analyzer requiring low-noise analog front-end and battery longevity. IC Role / Device Role / Timing Role: Signal processor managing transducer excitation, echo digitization (ADC), beamforming, and display interface (SAI/LCD-TFT). Use Value: Integrated 12-bit DAC and OPAMP with PGA enable programmable gain amplification; 160 KB SRAM buffers raw RF data before compression/transmission. |
Equivalent & Alternatives
The following parts are listed as comparable options for similar ultra-low-power ARM Cortex-M4 MCU applications.
| Alternative Part | Technical Difference | Application Difference | Selection Advice |
|---|---|---|---|
| STM32L476RG | Higher Flash (1 MB) and SRAM (128 KB), adds Ethernet MAC and Chrom-ART accelerator; no SMPS support - consumes 42 µA/MHz in run mode. | Better suited for GUI-rich HMI or networked gateways; lacks the STM32L452CEU3's 22 nA shutdown and batch acquisition mode for extreme energy harvesting. | Select when Ethernet or larger code footprint is required; avoid if sub-µA standby or SMPS integration is mandatory. |
| RA4M2 (R7FA4M2AD3CFM) | 48 MHz Cortex-M33, 256 KB Flash, 32 KB SRAM, 25 µA/MHz run, but no integrated DAC or OPAMP; uses Renesas' TrustZone security. | Stronger security focus and lower active power, but requires external analog components for sensor signal conditioning - increases BOM count and layout complexity. | Prefer for secure boot-critical applications where analog integration is handled externally; not drop-in for ADC/DAC-dependent designs. |
Compared with STM32L476RG and RA4M2, the STM32L452CEU3 uniquely balances ultra-low static power (22 nA shutdown), integrated analog (DAC+OPAMP+PGA), and SMPS-ready efficiency (36 µA/MHz), making it optimal for compact, battery-constrained systems needing self-contained signal processing.
Availability
STM32L452CEU3 is available at Aetrix Electronics and suitable for wearable health monitors, smart utility meters, industrial sensor nodes, and portable medical diagnostic devices requiring stable component supply across long product lifecycles.
Supply support for STM32L452CEU3 includes scheduled delivery planning, volume procurement assistance, BOM continuity management, traceable sourcing, and lifecycle availability coordination for OEM customers, industrial embedded developers, connected-device designers, and electronics production programs.
Manufacturer
STMicroelectronics is a global semiconductor leader headquartered in Geneva, Switzerland, designing and manufacturing microcontrollers, power management ICs, MEMS, and automotive semiconductors since 1987.
The STM32L4 series targets ultra-low-power embedded applications demanding extended battery life, robust security, and rich analog integration - specifically engineered for IoT edge nodes, portable medical equipment, and industrial automation sensors.
FAQ
Does STM32L452CEU3 support external SMPS, and what are the voltage requirements?
Yes, the STM32L452CEU3 supports external SMPS via dedicated VDD12 and VDD12_IO pins. It requires VDD12 = 1.05 V or 1.10 V (±3%) for optimal 36 µA/MHz run-mode efficiency. Internal LDO remains active for VDD core regulation unless explicitly disabled in power control registers.
What is the maximum ADC sampling rate with hardware oversampling enabled?
The 12-bit ADC achieves 5 Msps native sampling. With hardware oversampling (up to 256×), effective resolution increases to 16 bits at reduced throughput - e.g., 31.25 kSPS at 16-bit resolution. Oversampling is performed entirely in hardware without CPU intervention, preserving low-power operation.
Can the integrated OPAMP be configured as a transimpedance amplifier for photodiode sensing?
Yes, the single OPAMP supports non-inverting, inverting, and transimpedance configurations using internal or external feedback. Its rail-to-rail input/output, 10 MHz gain-bandwidth product, and programmable PGA stages allow direct photodiode current-to-voltage conversion with gain up to 32×, minimizing external component count.
Is the UFBGA64 package of STM32L452CEU3 compatible with standard reflow profiles?
Yes, the UFBGA64 (5×5 mm, 0.5 mm pitch) package complies with JEDEC J-STD-020D moisture sensitivity level 3 and supports standard Pb-free reflow profiles (peak 260 °C). STMicroelectronics specifies 20-second dwell above 217 °C and ramp rates ≤3 °C/s - fully compatible with automated SMT lines.
STM32L452CEU3 Specifications
- Product attributes
- Attribute value
- Manufacturer:
- STMicroelectronics
- Package/Case:
- 48-UFQFN Exposed Pad
- Series:
- STM32L4
- Packaging:
- Tray
- Product Status:
- Active
- Programmable:
- Not Verified
- Core Processor:
- ARM® Cortex®-M4
- Core Size:
- 32-Bit Single-Core
- Speed:
- 80MHz
- Connectivity:
- CANbus, I2C, IrDA, LINbus, QSPI, SAI, SPI, UART/USART, USB
- Peripherals:
- Brown-out Detect/Reset, DMA, PWM, WDT
- Number of I/O:
- 38
- Program Memory Size:
- 512KB (512K x 8)
- Program Memory Type:
- FLASH
- EEPROM Size:
- -
- RAM Size:
- 160K x 8
- Voltage - Supply (Vcc/Vdd):
- 1.71V ~ 3.6V
- Data Converters:
- A/D 10x12b; D/A 1x12b
- Oscillator Type:
- Internal
- Operating Temperature:
- -40°C ~ 125°C (TA)
- Grade:
- -
- Qualification:
- -
- Mounting Type:
- Surface Mount
- Supplier Device Package:
STM32L452CEU3 FAQ
1.How can I place an order for STM32L452CEU3 through Aetrix?
Please submit a Request for Quotation (RFQ) for STM32L452CEU3 on Aetrix. Our sales agent will provide a competitive quotation and guide you through the order confirmation once you accept the terms.
2.Are the price and stock information for STM32L452CEU3 reliable?
The price and inventory of STM32L452CEU3 are updated periodically and may fluctuate due to market conditions. Stock and pricing data are typically refreshed every 24 hours. Quotation validity for STM32L452CEU3 is usually 5 days.
3.What payment methods are accepted for STM32L452CEU3?
We accept Wire Transfer, PayPal, Credit Card, Western Union, MoneyGram, and Escrow for STM32L452CEU3 transactions.
Note: Certain payment methods may incur a processing fee.
4.How is shipping managed for STM32L452CEU3?
STM32L452CEU3 orders can be shipped via leading logistics carriers, including DHL, UPS, FedEx, TNT, or Registered Mail.
Once your STM32L452CEU3 order is processed, you will receive an email with the shipment details and tracking number.
Note: Tracking information may take up to 24 hours to appear. Express delivery typically takes 3–5 business days.
5.How can I obtain technical support or documentation for STM32L452CEU3?
For technical support, including STM32L452CEU3 datasheets, pinout diagrams, or application guidance, please contact our engineering support team. They can provide detailed documentation and assistance for your STM32L452CEU3 requirements.
6.How does Aetrix verify that STM32L452CEU3 is sourced from the original manufacturer or authorized distributors?
All STM32L452CEU3 products on Aetrix are procured from qualified distributors and authorized channels. Our dedicated quality assurance team conducts strict verification, including traceability checks and, if necessary, third-party testing. This ensures that STM32L452CEU3 meets industry standards.
7.What is the process for return or replacement of STM32L452CEU3?
All STM32L452CEU3 units undergo pre-shipment inspection (PSI). If there is an issue with STM32L452CEU3, returns or replacements are accepted under the following conditions:
1.Quantity discrepancies, incorrect items, or visible external defects (such as breakage or corrosion), acknowledged by Aetrix.
2.The issue is reported within 90 days of delivery.
3.The STM32L452CEU3 part is unused and in its original packaging.
Return procedure for STM32L452CEU3:
1.Submit a request within 90 days.
2.Obtain a Return Material Authorization (RMA) from Aetrix.
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