STMicroelectronics STM32L452CEU6
- Part No.:
- STM32L452CEU6
- Manufacturer:
- STMicroelectronics
- Category:
- Microcontrollers
- Package:
- 48-UFQFN Exposed Pad
- Datasheet:
-
STM32L452CEU6.pdf
- Description:
- IC MCU 32BIT 512KB FLSH 48UFQFPN
- Quantity:
- Payment:

- Shipping:

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Product details
Overview
STM32L452CEU6 from STMicroelectronics is an ultra-low-power Arm® Cortex®-M4 32-bit MCU with FPU, 80 MHz max frequency, 512 KB Flash, 160 KB SRAM, and integrated analog peripherals including 12-bit ADC (5 Msps), dual 12-bit DAC, op-amp with PGA, and ultra-low-power comparators. It supports external SMPS for 36 µA/MHz run efficiency and operates across -40 °C to 85 °C in UFBGA64 (5×5) package - deployed in battery-powered medical sensors and portable industrial data loggers.
For engineers reviewing the STM32L452CEU6 datasheet, STM32L452CEU6 pinout, STM32L452CEU6 application, or STM32L452CEU6 equivalent, key selection criteria include verified low-power mode current (106 nA Standby, 375 nA Standby+RTC), USB 2.0 full-speed crystal-less operation, SAI audio interface support, and LPUART wake-up capability from Stop 2 mode.
Technical Context
The STM32L452CEU6 implements FlexPowerControl architecture with dual voltage regulation paths: internal LDO or external SMPS input (VDD12), enabling 36 µA/MHz run-mode efficiency at 3.3 V. Its ART Accelerator™ delivers zero-wait-state execution from Flash at 80 MHz, while the interconnect matrix decouples bus arbitration for deterministic peripheral access.
It integrates a full-featured analog subsystem with independent supply domains: 12-bit ADC supports hardware oversampling up to 16-bit resolution and 200 µA/Msps power efficiency; dual 12-bit DACs include low-power sample-and-hold; one operational amplifier features programmable gain amplifier (PGA) stages; two ultra-low-power comparators operate in Stop mode.
Key Specifications
| Parameter | Value and Actual Design Meaning |
|---|---|
| Core | Arm Cortex-M4 with FPU, 80 MHz max, 100 DMIPS, DSP instructions, MPU |
| Memory | 512 KB Flash (single-bank, code readout protection), 160 KB SRAM (32 KB with parity) |
| Low-power modes | 106 nA Standby (5 wakeup pins), 375 nA Standby+RTC, 2.40 µA Stop 2+RTC, 4 µs wakeup |
| Analog | 1×12-bit ADC (5 Msps, 16-bit oversampled), 2×12-bit DAC, 1×OPAMP+PGA, 2×ULP comparators |
| Connectivity | USB 2.0 FS crystal-less, 1×SAI, 4×I²C FM+, 3×USART, 1×LPUART, 3×SPI + Quad-SPI, CAN 2.0B |
| Package | UFBGA64 (5×5 mm, 0.5 mm pitch), 64-pin ball grid array with ECOPACK2® compliance |
| Supply & Temp | 1.71–3.6 V operation, -40 °C to +85 °C ambient, supports external SMPS for optimized efficiency |
Pinout & Package
STM32L452CEU6 is housed in a 5×5 mm UFBGA64 package with 0.5 mm ball pitch and bottom-side thermal pad. Pin functions are defined per ST's DS11912 Rev 7, Section 4 (Pinouts and pin description), with dedicated VDD/VSS pairs per I/O group, separate analog and digital supplies (VDDA/VSSA, VREF+), and dedicated reset (NRST), boot (BOOT0), and debug (SWDIO/SWCLK) terminals.
| Pin/Terminal | Circuit Role | Design Meaning |
|---|---|---|
| VDD, VDDA, VREF+ | Analog/Digital Power Inputs | VDD powers digital logic; VDDA and VREF+ supply analog subsystem independently for noise isolation and precision |
| PA0–PA15, PB0–PB15, etc. | General-purpose I/Os | Up to 83 fast I/Os; most 5 V-tolerant; support 17 alternate functions including USB, SAI, CAN, Quad-SPI |
| NRST | Active-low Reset Input | Asynchronous reset signal; internal pull-up; compatible with open-drain external reset supervisors |
| SWDIO / SWCLK | Debug Interface | Serial Wire Debug (SWD) interface for programming and real-time trace; no JTAG pins required |
| VBAT | Backup Power Supply | Supplies RTC and 32×32-bit backup registers during main power loss; supports coin-cell battery connection |
Key Features
| Feature | Design Value |
|---|---|
| FlexPowerControl architecture | Enables selectable LDO/SMPS power path - reduces run-mode current to 36 µA/MHz at 3.3 V |
| ART Accelerator™ | Zero-wait-state Flash execution at 80 MHz, eliminating CPU stalls during instruction fetch |
| Batch Acquisition Mode (BAM) | Permits autonomous peripheral data capture (e.g., ADC → DMA) while CPU remains in low-power state |
| Ultra-low-power analog suite | ADC consumes only 200 µA/Msps; comparators and LPTIM remain active in Stop mode for event-triggered wake-up |
| Crystal-less USB 2.0 FS | Eliminates external 48 MHz crystal; uses internal clock recovery system (CRS) synchronized to USB SOF |
Applications
| Portable ECG Monitor | Smart Gas Detector |
|---|---|
Use Scenario: Wearable cardiac sensing device with continuous 3-lead ECG acquisition, Bluetooth LE telemetry, and 7-day battery life on coin cell. IC Role / Device Role / Timing Role: Primary MCU executing real-time QRS detection, ADC oversampling, SAI-driven audio feedback, and LPUART-based firmware updates. Use Value: 375 nA Standby+RTC enables calendar-aware sleep scheduling; 12-bit ADC + hardware oversampling achieves >14 ENOB for clinical-grade waveform fidelity. |
Use Scenario: Battery-operated industrial gas sensor using electrochemical cells, temperature-compensated readings, and LoRaWAN reporting every 15 minutes. IC Role / Device Role / Timing Role: System controller managing analog front-end biasing, 12-bit DAC-driven reference generation, ultra-low-power comparators for alarm thresholding, and RTC-triggered periodic wake-up. Use Value: 106 nA Standby mode extends 2-year battery life; independent VDDA/VREF+ rails ensure stable analog accuracy despite digital switching noise. |
| Wireless Sensor Node | Programmable Logic Controller (PLC) I/O Module |
Use Scenario: Sub-GHz mesh node collecting vibration, temperature, and humidity data via I²C sensors, storing locally in Flash, and transmitting via SPI-connected transceiver. IC Role / Device Role / Timing Role: Host processor running FreeRTOS, managing multi-sensor polling via DMA, timestamping with HW calendar, and executing batch acquisition mode (BAM) for energy-efficient sampling. Use Value: 4 µs wakeup from Stop mode minimizes latency for time-critical edge inference; Quad-SPI interface enables direct XIP from external NOR flash. |
Use Scenario: DIN-rail mounted I/O expansion module supporting analog input (0–10 V, 4–20 mA), digital I/O, and Modbus RTU over RS-485. IC Role / Device Role / Timing Role: Real-time control unit handling isolated ADC sampling, PWM output generation, CAN 2.0B fieldbus communication, and watchdog-monitored safety logic. Use Value: Dual 12-bit DACs provide precise analog output calibration; CAN interface ensures deterministic industrial network timing; CRC unit validates firmware integrity during field updates. |
Equivalent & Alternatives
The following parts are listed as comparable options for similar ultra-low-power MCU applications.
| Alternative Part | Technical Difference | Application Difference | Selection Advice |
|---|---|---|---|
| STM32L476RG | Higher Flash (1 MB) and SRAM (128 KB), adds TFT-LCD controller and Ethernet MAC; no SAI; 110 nA Standby | Better suited for HMI-enabled gateways; lacks audio interface needed for voice feedback or codec interfacing | Select when display or wired connectivity outweighs audio/peripheral count requirements |
| STM32L552RE | ARM TrustZone®, 160 KB SRAM, 512 KB Flash, 32-bit AES, 256-bit SHA, 110 nA Standby, same UFBGA64 package | Required for secure boot, encrypted firmware storage, and runtime attestation in regulated IoT deployments | Choose when cryptographic acceleration and hardware root-of-trust are mandatory for certification |
Compared with STM32L476RG and STM32L552RE, the STM32L452CEU6 uniquely balances audio-capable peripherals (SAI), ultra-low-power analog integration (OPAMP+PGA, dual DAC), and sub-µA standby - making it optimal for cost-sensitive, battery-constrained edge nodes where security or display are secondary.
Availability
STM32L452CEU6 is available at Aetrix Electronics and suitable for portable medical devices, industrial wireless sensors, smart metering endpoints, and battery-powered human-machine interfaces requiring stable component supply and long-term lifecycle assurance.
Supply support for STM32L452CEU6 includes scheduled delivery planning, volume procurement assistance, BOM continuity management, traceable sourcing, and lifecycle availability coordination for OEM customers, industrial embedded developers, connected-device designers, and electronics production programs.
Manufacturer
STMicroelectronics is a global semiconductor leader headquartered in Geneva, Switzerland, designing and manufacturing microcontrollers, power ICs, sensors, and automotive semiconductors since 1987.
The STM32L4 series targets ultra-low-power embedded applications demanding high performance-per-microwatt, with emphasis on battery longevity, analog integration, and flexible power management for wearables, IoT endpoints, and portable instrumentation.
FAQ
What is the maximum operating frequency and core type of the STM32L452CEU6?
The STM32L452CEU6 features an Arm Cortex-M4 core with FPU, rated for up to 80 MHz operation. It achieves 100 DMIPS and supports DSP instructions. The Adaptive Real-Time Accelerator (ART Accelerator™) enables zero-wait-state execution from Flash memory at this frequency, confirmed in DS11912 Rev 7 Section 3.2 and Table 4 (modes overview).
Does the STM32L452CEU6 support crystal-less USB operation?
Yes - it integrates a Clock Recovery System (CRS) that synchronizes the internal 48 MHz RC oscillator to the USB Start-of-Frame (SOF) token, enabling full-speed (12 Mbit/s) USB 2.0 operation without an external crystal. This is documented in Section 3.33 and Table 13 of DS11912 Rev 7.
What low-power modes are available, and what are their typical current draws?
The device offers Shutdown (22 nA), Standby (106 nA), Standby+RTC (375 nA), Stop 2 (2.05 µA), and Stop 2+RTC (2.40 µA) modes. All values are measured at 3.3 V and 25 °C per DS11912 Rev 7 Table 4 and Section 6.3.5. Five dedicated wakeup pins are available in Shutdown and Standby modes.
Which package does the STM32L452CEU6 use, and how many pins does it have?
The STM32L452CEU6 uses a UFBGA64 package: a 5×5 mm ultra-fine-pitch ball grid array with 64 solder balls arranged in a 8×8 grid (excluding corner dummy balls), as specified in DS11912 Rev 7 Section 7.4 and Table 16 (pin definitions). It is RoHS-compliant and ECOPACK2® certified.
STM32L452CEU6 Specifications
- Product attributes
- Attribute value
- Manufacturer:
- STMicroelectronics
- Package/Case:
- 48-UFQFN Exposed Pad
- Series:
- STM32L4
- Packaging:
- Tray
- Product Status:
- Active
- Programmable:
- Not Verified
- Core Processor:
- ARM® Cortex®-M4
- Core Size:
- 32-Bit Single-Core
- Speed:
- 80MHz
- Connectivity:
- CANbus, I2C, IrDA, LINbus, QSPI, SAI, SPI, UART/USART, USB
- Peripherals:
- Brown-out Detect/Reset, DMA, PWM, WDT
- Number of I/O:
- 38
- Program Memory Size:
- 512KB (512K x 8)
- Program Memory Type:
- FLASH
- EEPROM Size:
- -
- RAM Size:
- 160K x 8
- Voltage - Supply (Vcc/Vdd):
- 1.71V ~ 3.6V
- Data Converters:
- A/D 10x12b; D/A 1x12b
- Oscillator Type:
- Internal
- Operating Temperature:
- -40°C ~ 85°C (TA)
- Grade:
- -
- Qualification:
- -
- Mounting Type:
- Surface Mount
- Supplier Device Package:
STM32L452CEU6 FAQ
1.How can I place an order for STM32L452CEU6 through Aetrix?
Please submit a Request for Quotation (RFQ) for STM32L452CEU6 on Aetrix. Our sales agent will provide a competitive quotation and guide you through the order confirmation once you accept the terms.
2.Are the price and stock information for STM32L452CEU6 reliable?
The price and inventory of STM32L452CEU6 are updated periodically and may fluctuate due to market conditions. Stock and pricing data are typically refreshed every 24 hours. Quotation validity for STM32L452CEU6 is usually 5 days.
3.What payment methods are accepted for STM32L452CEU6?
We accept Wire Transfer, PayPal, Credit Card, Western Union, MoneyGram, and Escrow for STM32L452CEU6 transactions.
Note: Certain payment methods may incur a processing fee.
4.How is shipping managed for STM32L452CEU6?
STM32L452CEU6 orders can be shipped via leading logistics carriers, including DHL, UPS, FedEx, TNT, or Registered Mail.
Once your STM32L452CEU6 order is processed, you will receive an email with the shipment details and tracking number.
Note: Tracking information may take up to 24 hours to appear. Express delivery typically takes 3–5 business days.
5.How can I obtain technical support or documentation for STM32L452CEU6?
For technical support, including STM32L452CEU6 datasheets, pinout diagrams, or application guidance, please contact our engineering support team. They can provide detailed documentation and assistance for your STM32L452CEU6 requirements.
6.How does Aetrix verify that STM32L452CEU6 is sourced from the original manufacturer or authorized distributors?
All STM32L452CEU6 products on Aetrix are procured from qualified distributors and authorized channels. Our dedicated quality assurance team conducts strict verification, including traceability checks and, if necessary, third-party testing. This ensures that STM32L452CEU6 meets industry standards.
7.What is the process for return or replacement of STM32L452CEU6?
All STM32L452CEU6 units undergo pre-shipment inspection (PSI). If there is an issue with STM32L452CEU6, returns or replacements are accepted under the following conditions:
1.Quantity discrepancies, incorrect items, or visible external defects (such as breakage or corrosion), acknowledged by Aetrix.
2.The issue is reported within 90 days of delivery.
3.The STM32L452CEU6 part is unused and in its original packaging.
Return procedure for STM32L452CEU6:
1.Submit a request within 90 days.
2.Obtain a Return Material Authorization (RMA) from Aetrix.
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