STMicroelectronics STM32L452RET3
- Part No.:
- STM32L452RET3
- Manufacturer:
- STMicroelectronics
- Category:
- Microcontrollers
- Package:
- 64-LQFP
- Datasheet:
-
STM32L452RET3.pdf
- Description:
- IC MCU 32BIT 512KB FLASH 64LQFP
- Quantity:
- Payment:

- Shipping:

Inventory:351
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Product details
Overview
STM32L452RET3 from STMicroelectronics is an ultra-low-power Arm® Cortex®-M4 32-bit MCU with FPU, 80 MHz max frequency, 512 KB Flash, 160 KB SRAM, and integrated analog peripherals including 12-bit ADC (5 Msps), dual 12-bit DAC, op-amp with PGA, and RTC with hardware calendar. It supports external SMPS for 36 µA/MHz run efficiency and operates from -40 °C to +125 °C in LQFP64 package - deployed in battery-powered medical sensors and portable industrial data loggers.
For engineers reviewing the STM32L452RET3 datasheet, STM32L452RET3 pinout, STM32L452RET3 application, or STM32L452RET3 equivalent, key selection criteria include verified ultra-low-power modes (22 nA shutdown, 375 nA standby with RTC), dual-voltage domain support (VBAT + VDD), USB 2.0 full-speed crystal-less operation, and hardware-accelerated cryptographic primitives via TRNG and CRC unit.
Technical Context
The STM32L452RET3 implements an Adaptive Real-time Accelerator (ART Accelerator™) enabling zero-wait-state execution from Flash at 80 MHz, paired with a Memory Protection Unit (MPU) and interconnect matrix for deterministic peripheral arbitration. Its power architecture integrates dual regulators - internal LDO and external SMPS interface - allowing dynamic voltage scaling between Run, Stop 2, and Standby modes.
Clock system includes two PLLs (system and audio), auto-trimmed multispeed oscillator (±0.25%), and dedicated RTC clock domain with 32 kHz LSE input. Analog subsystem features independent supply domains, hardware oversampling up to 16-bit resolution on ADC, and low-power sample-and-hold on DAC channels - all synchronized via shared DMA controller with 14 channels.
Key Specifications
| Parameter | Value and Actual Design Meaning |
|---|---|
| Core | Arm Cortex-M4 with FPU, 80 MHz max, 100 DMIPS, ART Accelerator for 0-wait-state Flash execution |
| Memory | 512 KB Flash (single-bank, code readout protection), 160 KB SRAM (32 KB with hardware parity) |
| Power Consumption | 36 µA/MHz in SMPS-run mode; 22 nA in Shutdown; 375 nA in Standby with RTC enabled |
| Analog Peripherals | 1× 12-bit ADC (5 Msps, 16-bit oversampled), 2× 12-bit DAC, 1× op-amp with PGA, 2× comparators, 2.048 V/2.5 V buffered VREF |
| Communication | USB 2.0 FS crystal-less, 4× I²C FM+, 3× USART, 1× LPUART, 3× SPI, 1× SAI, CAN 2.0B, SDMMC, Quad-SPI |
| Timers & Control | 12× timers including 1× advanced-control (TIM1), 2× low-power (LPTIM1/2), SysTick, dual watchdogs |
| Package | LQFP64 (10 × 10 mm, 0.5 mm pitch), ECOPACK2® compliant, -40 °C to +125 °C operating range |
Pinout & Package
LQFP64 package with 64-pin quad flat pack, 0.5 mm pitch, exposed thermal pad, RoHS-compliant ECOPACK2® finish. Pin functions validated per STMicroelectronics DS11912 Rev 7 Section 4 (Pinouts and pin description).
| Pin/Terminal | Circuit Role | Design Meaning |
|---|---|---|
| VDD, VSS | Main power supply / ground | Dual-domain support: VDD powers digital core & I/O; VSS reference for analog & digital sections |
| VBAT | Battery backup supply | Supplies RTC and 32×32-bit backup registers during main power loss; enables calendar retention |
| PA0–PA15, PB0–PB15, PC0–PC15, PD0–PD2, PF0–PF1 | General-purpose I/O | Up to 51 GPIOs; most 5 V-tolerant; support 16 alternate functions including USB, CAN, SAI, and ADC inputs |
| NRST | Active-low reset input | Asynchronous reset with internal pull-up; compatible with external push-button or supervisor IC assertion |
| BOOT0 | Boot mode selection | High at power-up selects system memory bootloader; tied low for normal Flash execution |
| OSC_IN / OSC_OUT | External crystal oscillator interface | Supports 4–48 MHz crystals; optional for high-accuracy timing; bypassable with internal RC oscillators |
Key Features
| Feature | Design Value |
|---|---|
| FlexPowerControl architecture | Seven low-power modes with sub-µA quiescent current; 4 µs wakeup from Stop mode preserves real-time responsiveness |
| Hardware security primitives | True random number generator (TRNG), CRC calculation unit, 96-bit unique ID, and firewall for memory isolation |
| Integrated analog signal chain | ADC + DAC + op-amp + comparators + VREFBUF in single chip eliminates external signal conditioning components |
| USB crystal-less full-speed | Internal 48 MHz clock recovery system (CRS) enables USB communication without external crystal - reduces BOM cost and board space |
| Capacitive touch sensing | 21-channel TSC supporting touchkey, linear, and rotary sensors - enables intuitive HMI in portable devices without external IC |
Applications
| Portable Medical Sensor | Smart Energy Meter |
|---|---|
|
Use Scenario: Continuous ECG/SpO₂ monitoring in wearable patch sensor with coin-cell battery life target >2 years. IC Role / Device Role / Timing Role: Main controller executing signal acquisition, filtering, BLE packetization, and RTC-triggered wake-up for periodic transmission. Use Value: 22 nA Shutdown and 375 nA Standby with RTC enable multi-year battery life; integrated ADC/DAC/op-amp reduce analog front-end component count by 40%. |
Use Scenario: DIN-rail mounted electricity meter requiring metrology-grade sampling, tamper detection, and secure firmware updates. IC Role / Device Role / Timing Role: Metrology processor interfacing with isolated sigma-delta ADCs, managing secure boot, and timestamping events via hardware RTC. Use Value: Hardware parity on 32 KB SRAM ensures data integrity during power glitches; TRNG + CRC supports AES-128 encryption for firmware validation. |
| Industrial Wireless Node | Audio-enabled IoT Gateway |
|
Use Scenario: Battery-powered predictive maintenance node collecting vibration, temperature, and humidity data for LoRaWAN upload. IC Role / Device Role / Timing Role: Sensor fusion hub aggregating data from multiple I²C/SPI sensors, performing FFT preprocessing, and scheduling low-duty-cycle radio bursts. Use Value: 84 µA/MHz (LDO) and 36 µA/MHz (SMPS) enable efficient processing during active intervals; 14-channel DMA offloads CPU from sensor data movement. |
Use Scenario: Voice-controlled smart home gateway with local voice processing, USB audio playback, and SAI-connected codec. IC Role / Device Role / Timing Role: Audio subsystem controller handling I²S/SAI streaming, USB audio class compliance, and real-time DSP via Cortex-M4 FPU. Use Value: Dual PLLs decouple audio clock (48/44.1 MHz) from system clock; SAI supports master/slave stereo with programmable FIFO depth for jitter-free playback. |
Equivalent & Alternatives
The following parts are listed as comparable options for similar ultra-low-power MCU applications.
| Alternative Part | Technical Difference | Application Difference | Selection Advice |
|---|---|---|---|
| STM32L476RGT6 | Higher Flash (1 MB), larger SRAM (128 KB), added Chrom-ART accelerator and LCD-TFT controller | Targeted at HMI-rich applications (graphical displays); lacks integrated SMPS interface | Select when display interface or larger code footprint required; avoid if SMPS integration is mandatory for power optimization |
| STM32L552REY6Q | ARM TrustZone® security, 256 KB Flash, 256 KB SRAM, enhanced tamper detection, VDDIO2 domain | Designed for certified secure boot and firmware attestation; higher static power due to security logic | Choose for PSA Level 1–2 certified designs requiring hardware root of trust; not suitable for pure ultra-low-power sensor nodes |
Compared with STM32L476RGT6 and STM32L552REY6Q, the STM32L452RET3 uniquely balances sub-µA low-power operation, SMPS support, and integrated analog - making it optimal for cost-sensitive, battery-constrained edge nodes where security and graphics are secondary to energy efficiency.
Availability
STM32L452RET3 is available at Aetrix Electronics and suitable for portable medical sensors, smart energy meters, industrial wireless nodes, and audio-enabled IoT gateways requiring stable component supply across extended product lifecycles.
Supply support for STM32L452RET3 includes scheduled delivery planning, volume procurement assistance, BOM continuity management, traceable sourcing, and lifecycle availability coordination for OEM customers, industrial embedded developers, connected-device designers, and electronics production programs.
Manufacturer
STMicroelectronics is a global semiconductor leader headquartered in Geneva, Switzerland, specializing in microcontrollers, power management, analog, MEMS, and automotive ICs.
The STM32L4 series targets ultra-low-power embedded applications demanding extended battery life, rich analog integration, and robust security - optimized for wearables, industrial sensors, and smart metering.
FAQ
What is the maximum operating temperature rating for STM32L452RET3?
The STM32L452RET3 is qualified for operation from -40 °C to +125 °C ambient temperature, as specified in DS11912 Rev 7 Section 6.3.1. This extended range supports deployment in harsh industrial environments and under-hood automotive auxiliary systems, provided PCB thermal design maintains junction temperature within limits.
Does STM32L452RET3 support external SMPS control, and how is it implemented?
Yes - the STM32L452RET3 includes dedicated VDD12 and VDD12_IO pins to interface with external switched-mode power supplies. When enabled, SMPS mode reduces active current to 36 µA/MHz at 3.3 V, versus 84 µA/MHz in LDO mode. Configuration is handled via PWR_CR2 register bit SREN and requires proper external regulator feedback loop design.
Can the integrated op-amp be used in transimpedance configuration for photodiode signal conditioning?
Yes - the single rail-to-rail op-amp supports programmable gain (PGA mode) and can be configured as a transimpedance amplifier. Its input offset voltage (±1.5 mV typical) and bandwidth (1.5 MHz) are suitable for low-speed photodiode applications; external feedback resistor selection determines gain and noise performance per DS11912 Section 3.19.
Is USB crystal-less operation supported on STM32L452RET3, and what accuracy is guaranteed?
Yes - the internal clock recovery system (CRS) synchronizes the 48 MHz USB clock to the LSE (32.768 kHz) reference, achieving ±0.25% accuracy over temperature and voltage. This meets USB 2.0 full-speed specification without requiring an external 48 MHz crystal, reducing component count and layout complexity.
STM32L452RET3 Specifications
- Product attributes
- Attribute value
- Manufacturer:
- STMicroelectronics
- Package/Case:
- 64-LQFP
- Series:
- STM32L4
- Packaging:
- Tray
- Product Status:
- Active
- Programmable:
- Not Verified
- Core Processor:
- ARM® Cortex®-M4
- Core Size:
- 32-Bit Single-Core
- Speed:
- 80MHz
- Connectivity:
- CANbus, I2C, IrDA, LINbus, MMC/SD, QSPI, SAI, SPI, UART/USART, USB
- Peripherals:
- Brown-out Detect/Reset, DMA, PWM, WDT
- Number of I/O:
- 52
- Program Memory Size:
- 512KB (512K x 8)
- Program Memory Type:
- FLASH
- EEPROM Size:
- -
- RAM Size:
- 160K x 8
- Voltage - Supply (Vcc/Vdd):
- 1.71V ~ 3.6V
- Data Converters:
- A/D 16x12b; D/A 1x12b
- Oscillator Type:
- Internal
- Operating Temperature:
- -40°C ~ 125°C (TA)
- Grade:
- -
- Qualification:
- -
- Mounting Type:
- Surface Mount
- Supplier Device Package:
STM32L452RET3 FAQ
1.How can I place an order for STM32L452RET3 through Aetrix?
Please submit a Request for Quotation (RFQ) for STM32L452RET3 on Aetrix. Our sales agent will provide a competitive quotation and guide you through the order confirmation once you accept the terms.
2.Are the price and stock information for STM32L452RET3 reliable?
The price and inventory of STM32L452RET3 are updated periodically and may fluctuate due to market conditions. Stock and pricing data are typically refreshed every 24 hours. Quotation validity for STM32L452RET3 is usually 5 days.
3.What payment methods are accepted for STM32L452RET3?
We accept Wire Transfer, PayPal, Credit Card, Western Union, MoneyGram, and Escrow for STM32L452RET3 transactions.
Note: Certain payment methods may incur a processing fee.
4.How is shipping managed for STM32L452RET3?
STM32L452RET3 orders can be shipped via leading logistics carriers, including DHL, UPS, FedEx, TNT, or Registered Mail.
Once your STM32L452RET3 order is processed, you will receive an email with the shipment details and tracking number.
Note: Tracking information may take up to 24 hours to appear. Express delivery typically takes 3–5 business days.
5.How can I obtain technical support or documentation for STM32L452RET3?
For technical support, including STM32L452RET3 datasheets, pinout diagrams, or application guidance, please contact our engineering support team. They can provide detailed documentation and assistance for your STM32L452RET3 requirements.
6.How does Aetrix verify that STM32L452RET3 is sourced from the original manufacturer or authorized distributors?
All STM32L452RET3 products on Aetrix are procured from qualified distributors and authorized channels. Our dedicated quality assurance team conducts strict verification, including traceability checks and, if necessary, third-party testing. This ensures that STM32L452RET3 meets industry standards.
7.What is the process for return or replacement of STM32L452RET3?
All STM32L452RET3 units undergo pre-shipment inspection (PSI). If there is an issue with STM32L452RET3, returns or replacements are accepted under the following conditions:
1.Quantity discrepancies, incorrect items, or visible external defects (such as breakage or corrosion), acknowledged by Aetrix.
2.The issue is reported within 90 days of delivery.
3.The STM32L452RET3 part is unused and in its original packaging.
Return procedure for STM32L452RET3:
1.Submit a request within 90 days.
2.Obtain a Return Material Authorization (RMA) from Aetrix.
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