STMicroelectronics STM32L452RET6

Overview

STM32L452RET6 from STMicroelectronics is an ultra-low-power Arm® Cortex®-M4 32-bit MCU with FPU, operating up to 80 MHz (100 DMIPS), featuring 512 KB Flash, 160 KB SRAM, and integrated analog peripherals including 12-bit ADC (5 Msps), dual 12-bit DAC, op-amp with PGA, and RTC with hardware calendar - deployed in battery-powered industrial sensors and portable medical monitors.

For engineers reviewing the STM32L452RET6 datasheet, STM32L452RET6 pinout, STM32L452RET6 application, or STM32L452RET6 equivalent, key selection criteria include sub-µA low-power modes (375 nA Standby with RTC), SMPS-compatible 36 µA/MHz run efficiency, USB 2.0 full-speed crystal-less operation, and LQFP64 package compatibility with legacy STM32L4 design layouts.

Technical Context

The STM32L452RET6 implements FlexPowerControl architecture with five configurable low-power modes (Shutdown, Standby, Stop 2, Low-power Run, Run), supported by dual voltage regulators (LDO and external SMPS interface) and adaptive power gating across peripheral domains. Its ART Accelerator™ enables zero-wait-state execution from Flash at 80 MHz.

It integrates a full-featured analog subsystem: one 12-bit ADC with hardware oversampling (up to 16-bit effective resolution), two 12-bit DAC channels with sample-and-hold, two ultra-low-power comparators, and a programmable-gain op-amp - all supplied from independent VDDA rail for noise isolation and precision.

Key Specifications

Pinout & Package

LQFP64 package (10 × 10 mm, 0.5 mm pitch) with exposed thermal pad; RoHS-compliant and ECOPACK2® certified. Pinout validated per STMicroelectronics DS11912 Rev 7, Section 4 ("Pinouts and pin description").

Key Features

Applications

Equivalent & Alternatives

The following parts are listed as comparable options for similar ultra-low-power MCU applications.

Compared with STM32L476RG and STM32L552RE, the STM32L452RET6 delivers optimal balance of ultra-low quiescent current, integrated analog capability, and LQFP64 footprint - making it the most efficient choice for compact, long-life sensor and metering applications where security and display features are secondary.

Availability

STM32L452RET6 is available at Aetrix Electronics and suitable for portable medical devices, smart utility meters, industrial predictive maintenance sensors, and audio-enabled edge nodes requiring stable component supply across multi-year production cycles.

Supply support for STM32L452RET6 includes scheduled delivery planning, volume procurement assistance, BOM continuity management, traceable sourcing, and lifecycle availability coordination for OEM customers, industrial embedded developers, connected-device designers, and electronics production programs.

Manufacturer

STMicroelectronics is a global semiconductor leader headquartered in Geneva, Switzerland, designing and manufacturing microcontrollers, power management ICs, sensors, and automotive-grade components since 1987.

The STM32L4 series targets ultra-low-power embedded applications demanding extended battery life, rich analog integration, and real-time performance - optimized for wearables, IoT endpoints, and industrial monitoring systems.

FAQ

What is the maximum operating frequency and corresponding DMIPS rating?

The STM32L452RET6 operates at up to 80 MHz with an Adaptive Real-Time Accelerator (ART) enabling zero-wait-state Flash execution. It achieves 100 DMIPS (Dhrystone 2.1) and 273.55 CoreMark® (3.42 CoreMark/MHz), verified per STMicroelectronics DS11912 Rev 7, Section 3.1. This performance supports real-time sensor fusion and audio processing without external coprocessors.

Does the device support external SMPS, and what is the measured efficiency gain?

Yes - the STM32L452RET6 includes dedicated VDD12 and VDD12_IO pins and internal voltage scaling control to interface with external switched-mode power supplies. In SMPS mode, it achieves 36 µA/MHz (vs. 84 µA/MHz in LDO mode), a 57% reduction in active current, confirmed in DS11912 Rev 7 Table 28 and Section 3.9.3.

How many ADC channels are available, and what is their effective resolution with oversampling?

The device integrates one 12-bit ADC with up to 16 hardware-oversampled channels. With built-in digital filtering and oversampling (up to 256×), it achieves up to 16-bit effective resolution at reduced sampling rates (e.g., 15 kSPS), as specified in DS11912 Rev 7 Section 3.15 and Table 6.3.18.

Is USB 2.0 Full-Speed operation truly crystal-less, and how is timing accuracy maintained?

Yes - the STM32L452RET6 uses an internal Clock Recovery System (CRS) that locks the 48 MHz USB clock to the USB Start-of-Frame (SOF) token, achieving ±0.25% accuracy without external crystal. This is documented in DS11912 Rev 7 Sections 3.11 and 3.33, and validated per USB-IF compliance testing.