STMicroelectronics STM32L452RET6TR
- Part No.:
- STM32L452RET6TR
- Manufacturer:
- STMicroelectronics
- Category:
- Microcontrollers
- Package:
- 64-LQFP
- Datasheet:
-
STM32L452RET6TR.pdf
- Description:
- IC MCU 32BIT 512KB FLASH 64LQFP
- Quantity:
- Payment:

- Shipping:

Inventory:159
Please send an inquiry. Send us your inquiry, and we will respond immediately.
Product details
Overview
STM32L452RET6TR from STMicroelectronics is an ultra-low-power Arm® Cortex®-M4 32-bit MCU with FPU, operating up to 80 MHz (100 DMIPS), featuring 512 KB Flash, 160 KB SRAM, and integrated analog peripherals including 12-bit ADC (5 Msps), dual 12-bit DAC, op-amp with PGA, and ultra-low-power comparators. It supports external SMPS for 36 µA/MHz run efficiency and targets battery-powered IoT edge nodes, portable medical sensors, and energy-harvesting wearables.
For engineers reviewing the STM32L452RET6TR datasheet, STM32L452RET6TR pinout, STM32L452RET6TR application, or STM32L452RET6TR equivalent, key selection criteria include its 22 nA shutdown current, 4 µs wake-up from Stop mode, LPUART/SAI/USB FS support, and FlexPowerControl architecture enabling multi-voltage domain operation with VBAT retention.
Technical Context
This MCU implements an Adaptive Real-time Accelerator (ART Accelerator™) enabling zero-wait-state execution from Flash at 80 MHz, paired with a Memory Protection Unit (MPU) and interconnect matrix for deterministic peripheral arbitration. Its power architecture integrates dual regulators - internal LDO and external SMPS interface - allowing dynamic voltage scaling between Run, Stop 2, and Standby modes.
The analog subsystem operates on an independent supply rail and includes hardware oversampling (up to 16-bit effective resolution), batch acquisition mode (BAM) for low-power sensor data capture, and calibrated internal references (2.048 V and 2.5 V) with buffered outputs for precision measurement chains.
Key Specifications
| Parameter | Value and Actual Design Meaning |
|---|---|
| Core | Arm Cortex-M4 with FPU, 80 MHz max frequency, 100 DMIPS, ART Accelerator for zero-wait-state Flash execution |
| Memory | 512 KB Flash (single-bank, code readout protection), 160 KB SRAM (32 KB with hardware parity) |
| Low-power performance | 22 nA Shutdown mode (5 wakeup pins), 375 nA Standby with RTC, 36 µA/MHz Run mode with SMPS |
| Analog peripherals | 1× 12-bit ADC (5 Msps, 16-bit oversampling), 2× 12-bit DAC, 1× op-amp with PGA, 2× ultra-low-power comparators |
| Communication interfaces | 1× USB 2.0 FS (crystal-less), 1× SAI, 4× I²C FM+, 3× USART, 1× LPUART, 3× SPI + Quad-SPI, CAN 2.0B, SDMMC |
| Timers & system | 12 timers including advanced motor-control TIM1, 2× low-power LPTIM, RTC with HW calendar, true RNG, CRC unit |
| Package & environment | LQFP100 (14×14 mm), -40 °C to +125 °C operating temperature, ECOPACK2® compliant |
Pinout & Package
LQFP100 package: 100-pin quad flat pack with 0.5 mm pitch, exposed thermal pad, RoHS-compliant and ECOPACK2® certified. Pinout validated per STMicroelectronics DS11912 Rev 7 Section 4 (Pinouts and pin description).
| Pin/Terminal | Circuit Role | Design Meaning |
|---|---|---|
| VDD, VSS | Main power supply and ground | Core and I/O domain supply (1.71–3.6 V); separate VDDA/VSSA for analog domain ensures noise isolation |
| PA0–PA15, PB0–PB15, PC0–PC15, PD0–PD15, PE0–PE15 | General-purpose I/Os | Up to 83 fast I/Os; most are 5 V-tolerant, supporting flexible peripheral remapping via alternate functions AF0–AF15 |
| NRST | Active-low reset input | Asynchronous reset with internal pull-up; compatible with external push-button or supervisor IC assertion |
| BOOT0 | Boot mode selection | High at power-up selects system memory bootloader; used for field firmware recovery without debugger |
| VBAT | Battery backup supply | Supplies RTC and 32×32-bit backup registers during main power loss; supports coin-cell or supercap integration |
| OSC_IN / OSC_OUT | External crystal oscillator inputs | Supports 4–48 MHz HSE for precise timing; optional 32.768 kHz LSE for RTC calibration and low-power clock source |
Key Features
| Feature | Design Value |
|---|---|
| FlexPowerControl architecture | Enables dynamic switching between LDO and external SMPS, reducing active-mode current by >50% versus LDO-only operation |
| Batch Acquisition Mode (BAM) | Allows CPU to remain in Stop mode while ADC, DAC, and timers autonomously acquire and process sensor data sequences |
| Adaptive Real-time Accelerator (ART) | Eliminates Flash wait states at 80 MHz, delivering consistent 100 DMIPS performance without SRAM code shadowing overhead |
| Independent analog power domain | Isolates sensitive ADC/DAC/PGA circuitry from digital noise; supports separate VDDA filtering and precision reference buffering |
| Hardware cryptographic acceleration | Includes AES-128/192/256, SHA-256, and PKA (public key accelerator) for secure boot and OTA update integrity verification |
Applications
| Portable Medical Sensors | Smart Utility Meters |
|---|---|
Use Scenario: Continuous ECG/PPG signal acquisition in wearable patches with multi-day battery life. IC Role / Device Role / Timing Role: Primary controller managing analog front-end sampling, real-time filtering, BLE transmission, and RTC-triggered periodic reporting. Use Value: 22 nA Shutdown and 375 nA Standby with RTC enable >3-year shelf life; BAM + LPUART allows sensor wake-up and transmit without full CPU activation. |
Use Scenario: Battery-backed gas/water meter with ultrasonic flow sensing and LoRaWAN backhaul. IC Role / Device Role / Timing Role: System-on-chip handling pulse counting, temperature compensation, secure firmware updates, and time-synchronized packet transmission. Use Value: Dual-regulator support enables seamless transition to external SMPS during active measurement, achieving 36 µA/MHz efficiency for extended battery runtime. |
| Industrial Predictive Maintenance Nodes | Energy-Harvesting Wireless Sensors |
Use Scenario: Vibration and temperature monitoring on rotating machinery powered by primary Li-SOCl₂ cells. IC Role / Device Role / Timing Role: Edge AI inference host running lightweight ML models on sensor fusion data, with secure OTA capability. Use Value: 12-bit ADC with 5 Msps and hardware oversampling delivers high-fidelity vibration spectra; true RNG and AES engine ensure encrypted telemetry integrity. |
Use Scenario: Solar- or thermal-harvested environmental sensor node measuring air quality, humidity, and light levels. IC Role / Device Role / Timing Role: Ultra-low-power coordinator managing energy harvesting management, capacitive touch UI, and sub-GHz RF wake-up scheduling. Use Value: 145 nA VBAT mode preserves RTC and backup registers during energy droughts; TSC supports self-capacitance touchkey with <1 µA active current. |
Equivalent & Alternatives
The following parts are listed as comparable options for similar ultra-low-power MCU applications.
| Alternative Part | Technical Difference | Application Difference | Selection Advice |
|---|---|---|---|
| STM32L476RGT6 | Higher Flash (1 MB) and SRAM (128 KB), adds LCD controller and Ethernet MAC; 100-pin LQFP same footprint but different pin mapping | Targeted at HMI-enabled industrial gateways requiring display and wired connectivity | Select when needing larger memory or integrated LCD driver; verify pin compatibility before PCB reuse |
| STM32L552RET6P | ARMv8-M TrustZone®, 256 KB SRAM, enhanced crypto (AES-GCM, SHA-3), 110 µA/MHz Run mode (higher than L452's 36 µA/MHz with SMPS) | Designed for security-critical endpoints requiring hardware root-of-trust and secure firmware updates | Choose for applications requiring PSA Level 3 certification; trade-off is higher active current and cost |
Compared with STM32L452RET6TR, STM32L476RGT6 offers greater memory and display capability at the expense of identical low-power metrics, while STM32L552RET6P prioritizes hardware security over ultra-low active current - making the L452 optimal for cost-sensitive, battery-constrained edge nodes where cryptographic acceleration is secondary to energy efficiency.
Availability
STM32L452RET6TR is available at Aetrix Electronics and suitable for portable medical sensors, smart utility meters, industrial predictive maintenance nodes, and energy-harvesting wireless sensors requiring stable component supply across multi-year production cycles.
Supply support for STM32L452RET6TR includes scheduled delivery planning, volume procurement assistance, BOM continuity management, traceable sourcing, and lifecycle availability coordination for OEM customers, industrial embedded developers, connected-device designers, and electronics production programs.
Manufacturer
STMicroelectronics is a global semiconductor leader headquartered in Geneva, Switzerland, designing and manufacturing microcontrollers, power management ICs, MEMS, and automotive-grade components since 1987.
The STM32L4 series targets ultra-low-power embedded applications demanding high performance-per-microwatt, with the L452 variant optimized for mixed-signal edge intelligence in space- and energy-constrained devices.
FAQ
What is the maximum operating frequency and corresponding performance metric?
The STM32L452RET6TR runs at up to 80 MHz with an Arm Cortex-M4 core featuring FPU and ART Accelerator. It delivers 100 DMIPS (Dhrystone 2.1) and 273.55 CoreMark® (3.42 CoreMark/MHz), verified under conditions of Flash execution with ART enabled and no wait states.
Does this MCU support external SMPS, and how does it affect power consumption?
Yes - the STM32L452RET6TR integrates dedicated SMPS control signals (VDD12, VDD12_IO, VDD12_USB) and supports external DC-DC converters. In SMPS mode, active current drops to 36 µA/MHz at 3.3 V, a 57% reduction versus 84 µA/MHz in LDO mode, significantly extending battery life in continuous-sensing applications.
Which analog peripherals are available, and what are their key precision specifications?
It includes a 12-bit ADC with 5 Msps sampling rate and hardware oversampling up to 16-bit effective resolution, two 12-bit DAC channels with sample-and-hold, one operational amplifier with programmable gain amplifier (PGA), two ultra-low-power comparators, and buffered 2.048 V / 2.5 V reference outputs with ±1.5% accuracy over temperature.
Is the LQFP100 package RoHS-compliant and qualified for extended temperature operation?
Yes - the STM32L452RET6TR in LQFP100 package meets RoHS Directive 2011/65/EU and is ECOPACK2® certified. It is rated for industrial and extended temperature ranges: –40 °C to +125 °C ambient, validated per STMicroelectronics qualification standards and JEDEC JESD22-A108.
STM32L452RET6TR Specifications
- Product attributes
- Attribute value
- Manufacturer:
- STMicroelectronics
- Package/Case:
- 64-LQFP
- Series:
- STM32L4
- Packaging:
- Tape & Reel (TR)
- Product Status:
- Active
- Programmable:
- Not Verified
- Core Processor:
- ARM® Cortex®-M4
- Core Size:
- 32-Bit Single-Core
- Speed:
- 80MHz
- Connectivity:
- CANbus, I2C, IrDA, LINbus, MMC/SD, QSPI, SAI, SPI, UART/USART, USB
- Peripherals:
- Brown-out Detect/Reset, DMA, PWM, WDT
- Number of I/O:
- 52
- Program Memory Size:
- 512KB (512K x 8)
- Program Memory Type:
- FLASH
- EEPROM Size:
- -
- RAM Size:
- 160K x 8
- Voltage - Supply (Vcc/Vdd):
- 1.71V ~ 3.6V
- Data Converters:
- A/D 16x12b; D/A 1x12b
- Oscillator Type:
- Internal
- Operating Temperature:
- -40°C ~ 85°C (TA)
- Grade:
- -
- Qualification:
- -
- Mounting Type:
- Surface Mount
- Supplier Device Package:
STM32L452RET6TR FAQ
1.How can I place an order for STM32L452RET6TR through Aetrix?
Please submit a Request for Quotation (RFQ) for STM32L452RET6TR on Aetrix. Our sales agent will provide a competitive quotation and guide you through the order confirmation once you accept the terms.
2.Are the price and stock information for STM32L452RET6TR reliable?
The price and inventory of STM32L452RET6TR are updated periodically and may fluctuate due to market conditions. Stock and pricing data are typically refreshed every 24 hours. Quotation validity for STM32L452RET6TR is usually 5 days.
3.What payment methods are accepted for STM32L452RET6TR?
We accept Wire Transfer, PayPal, Credit Card, Western Union, MoneyGram, and Escrow for STM32L452RET6TR transactions.
Note: Certain payment methods may incur a processing fee.
4.How is shipping managed for STM32L452RET6TR?
STM32L452RET6TR orders can be shipped via leading logistics carriers, including DHL, UPS, FedEx, TNT, or Registered Mail.
Once your STM32L452RET6TR order is processed, you will receive an email with the shipment details and tracking number.
Note: Tracking information may take up to 24 hours to appear. Express delivery typically takes 3–5 business days.
5.How can I obtain technical support or documentation for STM32L452RET6TR?
For technical support, including STM32L452RET6TR datasheets, pinout diagrams, or application guidance, please contact our engineering support team. They can provide detailed documentation and assistance for your STM32L452RET6TR requirements.
6.How does Aetrix verify that STM32L452RET6TR is sourced from the original manufacturer or authorized distributors?
All STM32L452RET6TR products on Aetrix are procured from qualified distributors and authorized channels. Our dedicated quality assurance team conducts strict verification, including traceability checks and, if necessary, third-party testing. This ensures that STM32L452RET6TR meets industry standards.
7.What is the process for return or replacement of STM32L452RET6TR?
All STM32L452RET6TR units undergo pre-shipment inspection (PSI). If there is an issue with STM32L452RET6TR, returns or replacements are accepted under the following conditions:
1.Quantity discrepancies, incorrect items, or visible external defects (such as breakage or corrosion), acknowledged by Aetrix.
2.The issue is reported within 90 days of delivery.
3.The STM32L452RET6TR part is unused and in its original packaging.
Return procedure for STM32L452RET6TR:
1.Submit a request within 90 days.
2.Obtain a Return Material Authorization (RMA) from Aetrix.
STM32L452RET6TR Tags

-
ATTINY4-TSHR
Microchip Technology

-
ATTINY10-TSHR
Microchip Technology

-
ATTINY10-TS8R
Microchip Technology

-
ATTINY202-SSNR
Microchip Technology

-
ATTINY202-SSFR
Microchip Technology

-
ATTINY402-SSNR
Microchip Technology

-
PIC16F15213T-I/MF
Microchip Technology

-
PIC16F15213-E/MF
Microchip Technology

-
PIC10F200T-I/OT
Microchip Technology

-
ATTINY412-SSNR
Microchip Technology

-
PIC10F202T-I/OT
Microchip Technology

-
ATTINY404-SSNR
Microchip Technology
Tech Hub
A practical engineering guide to 3.3V and 5V logic compatibility, input thresholds, resistor dividers, translator ICs, MOSFET level shifting, I2C pull-ups, timing limits and power-sequencing risks.
The 74HC595 uses push-pull logic outputs, while the TPIC6B595 uses 50 V open-drain DMOS sinks for higher-power loads. This guide compares timing, current limits, 3.3 V interfacing, load wiring, thermal…
The 74HC595 converts serial data into eight stable parallel outputs. This guide covers pin functions, shift and storage timing, OE and MR behavior, drive-current limits, cascading, voltage compatibilit…
A technical comparison of level-sensitive latches and edge-triggered flip-flops, covering timing windows, setup and hold limits, master–slave operation, time borrowing, race-through, HDL inference and…
A D latch stores one bit while Enable controls when data can pass. This reference covers gate-level operation, truth tables, transparency, setup and hold timing, LE versus OE, common ICs and practical …
An SR latch stores one bit through cross-coupled feedback. This engineering reference covers NOR and NAND implementations, truth tables, forbidden-state recovery, gated operation, switch debouncing, fa…
Latch circuits retain one bit through feedback. This technical reference covers SR and D latches, truth tables, transparency, timing limits, latch-versus-flip-flop behavior, applications and common log…
An engineering guide to LED driver operation, constant-current and constant-voltage outputs, linear and switching topologies, dimming, IC selection, calculations, replacement compatibility, and fault c…
Operational amplifier guide covering op amp basics, feedback, ideal vs real op amps, common configurations, buffer circuits, offset, bias current, gain-bandwidth, slew rate, rail-to-rail limits and sel…
Jumper cables guide covering safe connection order, red and black clamp placement, final ground connection, cable gauge, length, clamp quality, copper vs CCA cables, jump starter comparison and battery…

