STMicroelectronics STM32L452REY6PTR
- Part No.:
- STM32L452REY6PTR
- Manufacturer:
- STMicroelectronics
- Category:
- Microcontrollers
- Package:
- 64-UFBGA, WLCSP
- Datasheet:
-
STM32L452REY6PTR.pdf
- Description:
- IC MCU 32BIT 512KB FLASH 64WLCSP
- Quantity:
- Payment:

- Shipping:

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Product details
Overview
STM32L452REY6PTR from STMicroelectronics is an ultra-low-power Arm® Cortex®-M4 32-bit MCU with FPU, operating up to 80 MHz (100 DMIPS), featuring 512 KB Flash, 160 KB SRAM, and integrated analog peripherals including 12-bit ADC (5 Msps), dual 12-bit DACs, op-amp with PGA, and ultra-low-power comparators. It supports external SMPS for 36 µA/MHz run efficiency and targets battery-powered IoT sensors, portable medical devices, and energy-harvesting edge nodes.
For engineers reviewing the STM32L452REY6PTR datasheet, STM32L452REY6PTR pinout, STM32L452REY6PTR application, or STM32L452REY6PTR equivalent, key selection criteria include verified ultra-low-power modes (22 nA Shutdown, 375 nA Standby+RTC), USB 2.0 full-speed crystal-less operation, SAI audio interface, and LQFP64 package compatibility with legacy STM32L4 designs.
Technical Context
The STM32L452REY6PTR implements FlexPowerControl architecture with dual voltage regulation paths: internal LDO (84 µA/MHz) and external SMPS support (36 µA/MHz), enabling dynamic power scaling across operating modes. Its ART Accelerator™ delivers zero-wait-state execution from Flash at 80 MHz while maintaining 335 ULPMark™ CP score.
It integrates a full-featured analog subsystem with independent supply domains: 12-bit ADC with hardware oversampling (up to 16-bit effective resolution), two 12-bit DAC channels with sample-and-hold, one rail-to-rail op-amp with programmable gain amplifier (PGA), and two ultra-low-power comparators - all operable in Stop 2 mode with 4 µs wakeup.
Key Specifications
| Parameter | Value and Actual Design Meaning |
|---|---|
| CPU Core | Arm Cortex-M4 with FPU, 80 MHz max frequency, 100 DMIPS performance - enables real-time DSP and control algorithms without external co-processors. |
| Memory | 512 KB Flash (single-bank, code readout protection), 160 KB SRAM (32 KB with hardware parity) - supports secure firmware updates and robust data logging in safety-critical applications. |
| Ultra-Low-Power Modes | 22 nA Shutdown (5 wakeup pins), 375 nA Standby+RTC, 2.40 µA Stop 2+RTC - extends coin-cell battery life to >10 years in always-on sensor nodes. |
| Analog Peripherals | 1× 12-bit ADC (5 Msps, 200 µA/Msps), 2× 12-bit DACs, 1× op-amp with PGA, 2× comparators - enables high-precision sensor signal conditioning and closed-loop analog control within single chip. |
| Communication Interfaces | USB 2.0 FS crystal-less, 1× SAI, 4× I²C (FM+), 4× USART/LPUART, 3× SPI + Quad-SPI, CAN 2.0B - supports mixed-signal edge devices requiring audio streaming, industrial comms, and fieldbus connectivity. |
| Package & Pin Count | LQFP64 (10×10 mm, 0.5 mm pitch), 51 GPIOs (most 5 V-tolerant) - provides compact footprint with sufficient I/O for sensor fusion, display, and peripheral expansion in space-constrained designs. |
Pinout & Package
LQFP64 package (10 × 10 mm, 0.5 mm pitch), RoHS-compliant and ECOPACK2® certified, optimized for reflow soldering and manual prototyping.
| Pin/Terminal | Circuit Role | Design Meaning |
|---|---|---|
| VDD, VDDA, VSS, VSSA | Power supply and ground (digital/analog domains) | Independent analog/digital power rails enable noise isolation for precision ADC/DAC operation; VDDA must be ≥ VDD for valid analog performance. |
| PA0–PA15, PB0–PB15, PC0–PC15, PD0–PD2 | General-purpose I/Os | 51 total GPIOs; most are 5 V-tolerant, supporting mixed-voltage interfacing with legacy peripherals and sensors without level shifters. |
| PA2/PA3, PB10/PB11 | USART1/USART3 TX/RX | Dedicated UART pins with LIN, IrDA, and modem support - enable direct connection to automotive diagnostics or low-power wireless modules. |
| PA9/PA10 | USB_DM/USB_DP | Crystal-less USB 2.0 full-speed interface - eliminates external 48 MHz crystal, reducing BOM cost and PCB area in portable endpoints. |
| PA4–PA7 | ADC1_IN4–ADC1_IN7 | Analog input channels with hardware oversampling capability - allow 16-bit effective resolution for high-fidelity sensor acquisition (e.g., thermocouple, strain gauge). |
| PB15 | SAI1_SD_A | Serial Audio Interface data line - supports I²S, PCM, or AC'97 protocols for direct connection to MEMS microphones or audio codecs in voice-enabled edge devices. |
Key Features
| Feature | Design Value |
|---|---|
| FlexPowerControl architecture | Enables seamless transition between 22 nA Shutdown and 80 MHz active operation - critical for duty-cycled battery-powered telemetry systems. |
| ART Accelerator™ with prefetch | Delivers zero-wait-state Flash execution at 80 MHz while maintaining 3.42 CoreMark/MHz - eliminates need for external RAM caching in real-time control loops. |
| Batch Acquisition Mode (BAM) | Permits CPU sleep during burst ADC sampling sequences - reduces average current by >40% in periodic sensor monitoring applications. |
| Embedded SMPS controller interface | Direct control of external DC-DC converter (VDD12 supply) - achieves 36 µA/MHz run efficiency, cutting power vs. LDO-only operation by 57%. |
| Hardware cryptographic acceleration | True random number generator (RNG) + CRC unit + 96-bit unique ID - supports secure boot, firmware signing, and device identity management per PSA Level 1 requirements. |
Applications
| Wearable Health Monitor | Smart Utility Meter |
|---|---|
Use Scenario: Continuous ECG/PPG signal acquisition with Bluetooth LE telemetry and on-device arrhythmia detection. IC Role / Device Role / Timing Role: Primary MCU executing sensor fusion, real-time filtering, and BLE stack; RTC maintains accurate time-stamping across deep sleep cycles. Use Value: 375 nA Standby+RTC and 4 µs wakeup from Stop 2 enable sub-µA average current during sensor idle periods, extending CR2032 battery life beyond 2 years. |
Use Scenario: AMI meter with ultrasonic flow sensing, tamper detection, and NB-IoT backhaul communication. IC Role / Device Role / Timing Role: System controller managing pulse counting, metrology ADC sampling, secure firmware updates, and low-duty-cycle cellular transmission. Use Value: Dual ADC/DAC + op-amp + comparators allow single-chip analog front-end for differential pressure measurement and leak detection - eliminating 3 discrete signal-chain ICs. |
| Industrial Predictive Maintenance Node | Energy-Harvesting Wireless Sensor |
Use Scenario: Vibration and temperature monitoring on rotating machinery using MEMS accelerometers and thermistors, with local FFT analysis and alert triggering. IC Role / Device Role / Timing Role: Real-time DSP engine performing 1024-point FFT on 10 kHz sampled data; LPUART wakes CPU only on scheduled upload windows. Use Value: 100 DMIPS + ART Accelerator enables 2.1 ms FFT execution in SRAM - meets <5 ms latency requirement for Class A industrial alarms without external DSP. |
Use Scenario: Solar-powered environmental sensor node measuring light, humidity, and CO₂, transmitting hourly via LoRaWAN. IC Role / Device Role / Timing Role: Power-aware system manager coordinating energy harvesting PMIC, sensor polling, and radio duty cycling via LPTIM2 and RTC alarms. Use Value: 22 nA Shutdown mode with 5 wakeup pins allows full system hibernation between measurements - maximizes energy capture from microwatt-scale harvesters. |
Equivalent & Alternatives
The following parts are listed as comparable options for similar ultra-low-power MCU applications.
| Alternative Part | Technical Difference | Application Difference | Selection Advice |
|---|---|---|---|
| STM32L476RG | Higher Flash (1 MB) and SRAM (128 KB), adds TFT-LCD controller and Ethernet MAC; 110 µA/MHz run (LDO), no SMPS interface. | Better suited for HMI-rich applications (e.g., smart thermostats); lacks SMPS efficiency for multi-year battery life. | Select when display interface or larger code space outweighs ultra-low-power priority. |
| STM32U575ZIT6 | ARMv8-M TrustZone®, 2.5x lower active power (18 µA/MHz @ 160 MHz), 2 MB Flash, but LQFP100-only; no SAI or USB crystal-less mode. | Targets PSA Certified Level 3 security use cases (e.g., payment terminals); incompatible pinout prevents drop-in replacement. | Choose for next-gen secure edge nodes where certification and peak efficiency supersede legacy peripheral compatibility. |
Compared with STM32L476RG, the STM32L452REY6PTR trades memory capacity and display features for superior ultra-low-power operation and SMPS integration; versus STM32U575ZIT6, it offers proven LQFP64 pin compatibility and crystal-less USB - critical for cost-sensitive, size-constrained designs already in production.
Availability
STM32L452REY6PTR is available at Aetrix Electronics and suitable for wearable health monitors, smart utility meters, industrial predictive maintenance nodes, and energy-harvesting wireless sensors requiring stable component supply across long-lifecycle deployments.
Supply support for STM32L452REY6PTR includes scheduled delivery planning, volume procurement assistance, BOM continuity management, traceable sourcing, and lifecycle availability coordination for OEM customers, industrial embedded developers, connected-device designers, and electronics production programs.
Manufacturer
STMicroelectronics is a global semiconductor leader headquartered in Geneva, Switzerland, designing and manufacturing microcontrollers, power management ICs, sensors, and analog components for industrial, automotive, and consumer markets.
The STM32L4 series is engineered for ultra-low-power embedded applications demanding extended battery life, rich analog integration, and real-time performance - targeting IoT edge nodes, portable medical devices, and smart metering systems.
FAQ
What is the maximum operating frequency and corresponding power consumption in Run mode?
The STM32L452REY6PTR operates up to 80 MHz. In Run mode with internal LDO, typical current is 84 µA/MHz at 3.3 V; with external SMPS (VDD12 = 1.10 V), it drops to 36 µA/MHz - verified per DS11912 Rev 7 Table 28. This enables deterministic real-time execution while minimizing active power in battery-constrained systems.
Does this MCU support crystal-less USB operation, and what are the timing accuracy implications?
Yes, the STM32L452REY6PTR integrates a USB 2.0 full-speed crystal-less solution using its internal 48 MHz oscillator with clock recovery system (CRS). According to DS11912 Rev 7 Section 3.33, it achieves ±0.25% accuracy over temperature and voltage - sufficient for USB suspend/resume and enumeration without external crystal, reducing BOM cost and board area.
How many analog inputs does the integrated ADC support, and what is its effective resolution with oversampling?
The 12-bit ADC supports up to 16 channels (e.g., PA0–PA7, PB0–PB1, PC0–PC5). With hardware oversampling (up to 256x), it achieves up to 16-bit effective resolution at reduced sampling rates - confirmed in DS11912 Rev 7 Section 3.15 and Table 6.3.18, enabling high-precision sensor measurements without external sigma-delta converters.
What low-power modes retain RTC functionality, and what is the minimum supply current in that state?
Standby mode with RTC enabled consumes 375 nA (DS11912 Rev 7 Section 3.9.4, Table 4), retaining calendar, alarms, and 32×32-bit backup registers powered by VBAT. This mode supports wake-up events from RTC alarm, tamper, or external pins - essential for time-triggered sensor polling in multi-year deployments.
STM32L452REY6PTR Specifications
- Product attributes
- Attribute value
- Manufacturer:
- STMicroelectronics
- Package/Case:
- 64-UFBGA, WLCSP
- Series:
- STM32L4
- Packaging:
- Tape & Reel (TR)
- Product Status:
- Active
- Programmable:
- Not Verified
- Core Processor:
- ARM® Cortex®-M4
- Core Size:
- 32-Bit Single-Core
- Speed:
- 80MHz
- Connectivity:
- CANbus, I2C, IrDA, LINbus, MMC/SD, QSPI, SAI, SPI, UART/USART, USB
- Peripherals:
- Brown-out Detect/Reset, DMA, PWM, WDT, (External SMPS Required)
- Number of I/O:
- 52
- Program Memory Size:
- 512KB (512K x 8)
- Program Memory Type:
- FLASH
- EEPROM Size:
- -
- RAM Size:
- 160K x 8
- Voltage - Supply (Vcc/Vdd):
- 1.71V ~ 3.6V
- Data Converters:
- A/D 16x12b; D/A 1x12b
- Oscillator Type:
- Internal
- Operating Temperature:
- -40°C ~ 85°C (TA)
- Grade:
- -
- Qualification:
- -
- Mounting Type:
- Surface Mount
- Supplier Device Package:
STM32L452REY6PTR FAQ
1.How can I place an order for STM32L452REY6PTR through Aetrix?
Please submit a Request for Quotation (RFQ) for STM32L452REY6PTR on Aetrix. Our sales agent will provide a competitive quotation and guide you through the order confirmation once you accept the terms.
2.Are the price and stock information for STM32L452REY6PTR reliable?
The price and inventory of STM32L452REY6PTR are updated periodically and may fluctuate due to market conditions. Stock and pricing data are typically refreshed every 24 hours. Quotation validity for STM32L452REY6PTR is usually 5 days.
3.What payment methods are accepted for STM32L452REY6PTR?
We accept Wire Transfer, PayPal, Credit Card, Western Union, MoneyGram, and Escrow for STM32L452REY6PTR transactions.
Note: Certain payment methods may incur a processing fee.
4.How is shipping managed for STM32L452REY6PTR?
STM32L452REY6PTR orders can be shipped via leading logistics carriers, including DHL, UPS, FedEx, TNT, or Registered Mail.
Once your STM32L452REY6PTR order is processed, you will receive an email with the shipment details and tracking number.
Note: Tracking information may take up to 24 hours to appear. Express delivery typically takes 3–5 business days.
5.How can I obtain technical support or documentation for STM32L452REY6PTR?
For technical support, including STM32L452REY6PTR datasheets, pinout diagrams, or application guidance, please contact our engineering support team. They can provide detailed documentation and assistance for your STM32L452REY6PTR requirements.
6.How does Aetrix verify that STM32L452REY6PTR is sourced from the original manufacturer or authorized distributors?
All STM32L452REY6PTR products on Aetrix are procured from qualified distributors and authorized channels. Our dedicated quality assurance team conducts strict verification, including traceability checks and, if necessary, third-party testing. This ensures that STM32L452REY6PTR meets industry standards.
7.What is the process for return or replacement of STM32L452REY6PTR?
All STM32L452REY6PTR units undergo pre-shipment inspection (PSI). If there is an issue with STM32L452REY6PTR, returns or replacements are accepted under the following conditions:
1.Quantity discrepancies, incorrect items, or visible external defects (such as breakage or corrosion), acknowledged by Aetrix.
2.The issue is reported within 90 days of delivery.
3.The STM32L452REY6PTR part is unused and in its original packaging.
Return procedure for STM32L452REY6PTR:
1.Submit a request within 90 days.
2.Obtain a Return Material Authorization (RMA) from Aetrix.
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