STMicroelectronics STM32L452REY6TR
- Part No.:
- STM32L452REY6TR
- Manufacturer:
- STMicroelectronics
- Category:
- Microcontrollers
- Package:
- 64-UFBGA, WLCSP
- Datasheet:
-
STM32L452REY6TR.pdf
- Description:
- IC MCU 32BIT 512KB FLASH 64WLCSP
- Quantity:
- Payment:

- Shipping:

Inventory:13,999
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Product details
Overview
STM32L452REY6TR from STMicroelectronics is an ultra-low-power Arm® Cortex®-M4 32-bit MCU with FPU, operating up to 80 MHz and delivering 100 DMIPS. It integrates 512 KB Flash, 160 KB SRAM (32 KB with hardware parity), and advanced analog peripherals including a 12-bit 5 Msps ADC, dual 12-bit DACs, and an operational amplifier with PGA-targeting battery-powered portable medical sensors and industrial IoT edge nodes.
For engineers reviewing the STM32L452REY6TR datasheet, STM32L452REY6TR pinout, STM32L452REY6TR application, or STM32L452REY6TR equivalent, key selection criteria include verified Stop 2 mode current (2.40 µA with RTC), SMPS-enabled 36 µA/MHz run efficiency, 83 GPIOs (most 5 V-tolerant), and integrated USB 2.0 full-speed crystal-less interface for compact embedded designs.
Technical Context
The device implements FlexPowerControl architecture with seven low-power modes-including Shutdown (22 nA), Standby with RTC (375 nA), and Stop 2 (2.40 µA)-enabled by dual voltage regulators (LDO/SMPS) and hardware-accelerated power state transitions. Its ART Accelerator™ enables zero-wait-state execution from Flash at 80 MHz, while the interconnect matrix decouples bus arbitration for deterministic peripheral access.
Clock system includes dual PLLs (system/audio), auto-trimmed multispeed oscillator (±0.25%), and dedicated LSE-driven RTC with hardware calendar and calibration. Analog subsystem features independent supply domains, 2.048 V/2.5 V buffered reference, and 21-capacitive-sensing channels supporting touchkey and rotary interfaces.
Key Specifications
| Parameter | Value and Actual Design Meaning |
|---|---|
| Core | Arm Cortex-M4 with FPU, 80 MHz max, 100 DMIPS, MPU, DSP instructions |
| Memory | 512 KB Flash (single bank, code readout protection), 160 KB SRAM (32 KB with parity) |
| Power Modes | Shutdown: 22 nA; Standby w/RTC: 375 nA; Stop 2 w/RTC: 2.40 µA; Run @3.3 V SMPS: 36 µA/MHz |
| Analog Peripherals | 1×12-bit 5 Msps ADC (16-bit oversampling), 2×12-bit DACs, 1×OPAMP+PGA, 2×ULP comparators, VREFBUF |
| Connectivity | USB 2.0 FS crystal-less, 4×I²C FM+, 3×USART, 1×LPUART, 3×SPI + Quad-SPI, SAI, CAN 2.0B, SDMMC |
| Timers & I/O | 12 timers (incl. advanced TIM1, 2×LPTIM), 83 fast I/Os (most 5 V-tolerant), 21-channel TSC |
| Package | UFBGA64 (5 × 5 mm, 0.4 mm pitch), ECOPACK2® compliant |
Pinout & Package
STM32L452REY6TR is housed in a 64-ball UFBGA package (5 × 5 mm, 0.4 mm pitch) with 51 user I/Os, optimized for space-constrained PCB layouts and thermal performance in portable applications.
| Pin/Terminal | Circuit Role | Design Meaning |
|---|---|---|
| VDD, VSS | Main power supply and ground | Supports 1.71–3.6 V operation; separate VDDA/VSSA pins for analog domain isolation |
| VBAT | Backup power supply | Enables RTC and 32×32-bit backup registers during main power loss (145 nA retention) |
| PA0–PA15, PB0–PB15, PC0–PC15, PD0–PD15, PE0–PE15 | General-purpose I/Os | 83 total GPIOs; most 5 V-tolerant; support multiple alternate functions (AF0–AF15) and wakeup capability |
| OSC_IN/OSC_OUT | External high-speed crystal input/output | Supports 4–48 MHz crystals; optional bypass for external clock source |
| LSE_IN/LSE_OUT | Low-speed crystal for RTC | Drives 32.768 kHz crystal; enables calendar, alarms, and calibration in all low-power modes |
| NRST | Active-low reset input | Asynchronous reset with internal pull-up; supports external reset assertion and brown-out detection |
| SWDIO/SWCLK | Serial Wire Debug interface | 2-pin debug port for programming and real-time trace; compatible with standard SWD tools |
Key Features
| Feature | Design Value |
|---|---|
| FlexPowerControl architecture | Seven configurable low-power modes with sub-µA retention and 4 µs wake-up from Stop |
| ART Accelerator™ | Zero-wait-state Flash execution at 80 MHz, eliminating cache misses in deterministic real-time tasks |
| Dual voltage regulation | Integrated LDO + external SMPS support enables 36 µA/MHz run efficiency at 3.3 V |
| Hardware crypto & security | True RNG, CRC unit, 96-bit unique ID, and firewall for memory protection and secure boot |
| Capacitive sensing controller (TSC) | 21-channel touch sensing with built-in charge transfer, enabling robust touchkey/rotary interfaces without external ICs |
Applications
| Wearable Health Monitor | Smart Utility Meter |
|---|---|
Use Scenario: Continuous ECG/PPG signal acquisition and local anomaly detection in coin-cell-powered wrist-worn devices. IC Role / Device Role / Timing Role: Primary MCU executing sensor fusion algorithms, managing ultra-low-power ADC sampling bursts, and maintaining RTC-synchronized data logging. Use Value: 2.40 µA Stop 2 mode with RTC preserves timekeeping and enables scheduled wake-up for periodic measurements-extending battery life beyond 2 years on CR2032. | Use Scenario: Battery-backed gas/water meter with pulse counting, wireless reporting (LoRaWAN/NB-IoT), and tamper detection. IC Role / Device Role / Timing Role: System controller handling metrology ADC, secure firmware updates via LPUART, and long-term timestamped event logging. Use Value: 375 nA Standby mode with RTC ensures accurate billing intervals and calendar-based tariff switching without external timekeeping IC. |
| Industrial Wireless Sensor Node | Portable Diagnostic Instrument |
Use Scenario: Self-powered vibration/temperature node using energy harvesting, transmitting data via BLE or Sub-GHz RF. IC Role / Device Role / Timing Role: Host processor interfacing with MEMS sensors, managing DMA-driven burst sampling, and coordinating radio sleep/wake cycles. Use Value: 83 GPIOs with 5 V tolerance simplify direct connection to legacy industrial sensors; SMPS mode cuts active power by >50% vs. LDO-only operation. | Use Scenario: Handheld ultrasound or point-of-care blood analyzer requiring analog front-end control, audio feedback, and USB-C data export. IC Role / Device Role / Timing Role: Mixed-signal controller driving SAI-connected audio codec, synchronizing dual DAC outputs for analog waveform generation, and managing USB 2.0 crystal-less enumeration. Use Value: Integrated SAI + USB FS eliminates external PHY and audio bridge ICs, reducing BOM count and PCB area by 30%. |
Equivalent & Alternatives
The following parts are listed as comparable options for similar ultra-low-power MCU applications.
| Alternative Part | Technical Difference | Application Difference | Selection Advice |
|---|---|---|---|
| STM32L476RGV6 | Higher Flash (1 MB), added Ethernet MAC and Chrom-ART accelerator; no SAI or SDMMC | Better suited for GUI-rich HMI or networked gateways; lacks audio interface for voice-enabled edge devices | Select when needing larger code space and display acceleration-not for audio-centric or battery-limited use cases |
| STM32L552RET6 | ARM TrustZone®, 256 KB SRAM, 512 KB Flash, enhanced security peripherals; higher active current (42 µA/MHz SMPS) | Required for PSA Level 3 certified firmware; adds secure boot, cryptographic accelerators, and memory isolation | Choose for regulated medical or payment terminals where hardware-enforced security is mandatory |
Compared with STM32L476RGV6, STM32L452REY6TR offers superior audio integration and lower static power, while STM32L552RET6 trades some energy efficiency for certified security-making the L452 optimal for cost-sensitive, battery-constrained audio/IoT endpoints where TrustZone is unnecessary.
Availability
STM32L452REY6TR is available at Aetrix Electronics and suitable for wearable health monitors, smart utility meters, industrial wireless sensor nodes, and portable diagnostic instruments requiring stable component supply across multi-year production cycles.
Supply support for STM32L452REY6TR includes scheduled delivery planning, volume procurement assistance, BOM continuity management, traceable sourcing, and lifecycle availability coordination for OEM customers, industrial embedded developers, connected-device designers, and electronics production programs.
Manufacturer
STMicroelectronics is a global semiconductor leader headquartered in Geneva, designing and manufacturing microcontrollers, power management ICs, sensors, and analog components for industrial, automotive, and consumer markets.
The STM32L4 series targets ultra-low-power embedded applications demanding extended battery life, rich analog integration, and real-time responsiveness-optimized for portable medical, metering, and intelligent edge devices.
FAQ
What is the maximum operating frequency and corresponding performance metric?
The STM32L452REY6TR operates at up to 80 MHz using its Arm Cortex-M4 core with FPU. At this frequency, it delivers 100 DMIPS (Dhrystone 2.1) and achieves 273.55 CoreMark® (3.42 CoreMark/MHz). These metrics are validated with ART Accelerator™ enabled and zero-wait-state Flash execution, ensuring deterministic real-time behavior in time-critical firmware.
Does STM32L452REY6TR support external SMPS, and what power savings does it enable?
Yes, the device supports external SMPS via dedicated VDD12 and VDD12_IO pins. When powered by an external SMPS at 1.10 V, it achieves 36 µA/MHz in Run mode-reducing active power consumption by over 50% compared to LDO-mode operation (84 µA/MHz). This configuration requires proper external regulator design per Section 3.9.3 of DS11912 Rev 7.
How many capacitive sensing channels does the TSC support, and what sensor topologies are implemented?
The Touch Sensing Controller (TSC) supports 21 capacitive sensing channels, configured as 16 GPIOs plus 5 additional channels. It implements charge-transfer acquisition with built-in spread-spectrum and noise filtering, enabling robust touchkey, linear slider, and rotary wheel interfaces-without requiring external RC networks or dedicated touch ICs.
Is USB 2.0 Full-Speed operation truly crystal-less, and what accuracy requirements apply?
Yes, the integrated USB 2.0 Full-Speed PHY operates crystal-less using the internal 48 MHz oscillator with Clock Recovery System (CRS). CRS auto-trims the oscillator against USB SOF packets, maintaining ±0.25% accuracy-meeting USB specification requirements without external crystal or clock source, saving board space and BOM cost.
STM32L452REY6TR Specifications
- Product attributes
- Attribute value
- Manufacturer:
- STMicroelectronics
- Package/Case:
- 64-UFBGA, WLCSP
- Series:
- STM32L4
- Packaging:
- Tape & Reel (TR)
- Product Status:
- Active
- Programmable:
- Not Verified
- Core Processor:
- ARM® Cortex®-M4
- Core Size:
- 32-Bit Single-Core
- Speed:
- 80MHz
- Connectivity:
- CANbus, I2C, IrDA, LINbus, MMC/SD, QSPI, SAI, SPI, UART/USART, USB
- Peripherals:
- Brown-out Detect/Reset, DMA, PWM, WDT
- Number of I/O:
- 52
- Program Memory Size:
- 512KB (512K x 8)
- Program Memory Type:
- FLASH
- EEPROM Size:
- -
- RAM Size:
- 160K x 8
- Voltage - Supply (Vcc/Vdd):
- 1.71V ~ 3.6V
- Data Converters:
- A/D 16x12b; D/A 1x12b
- Oscillator Type:
- Internal
- Operating Temperature:
- -40°C ~ 85°C (TA)
- Grade:
- -
- Qualification:
- -
- Mounting Type:
- Surface Mount
- Supplier Device Package:
STM32L452REY6TR FAQ
1.How can I place an order for STM32L452REY6TR through Aetrix?
Please submit a Request for Quotation (RFQ) for STM32L452REY6TR on Aetrix. Our sales agent will provide a competitive quotation and guide you through the order confirmation once you accept the terms.
2.Are the price and stock information for STM32L452REY6TR reliable?
The price and inventory of STM32L452REY6TR are updated periodically and may fluctuate due to market conditions. Stock and pricing data are typically refreshed every 24 hours. Quotation validity for STM32L452REY6TR is usually 5 days.
3.What payment methods are accepted for STM32L452REY6TR?
We accept Wire Transfer, PayPal, Credit Card, Western Union, MoneyGram, and Escrow for STM32L452REY6TR transactions.
Note: Certain payment methods may incur a processing fee.
4.How is shipping managed for STM32L452REY6TR?
STM32L452REY6TR orders can be shipped via leading logistics carriers, including DHL, UPS, FedEx, TNT, or Registered Mail.
Once your STM32L452REY6TR order is processed, you will receive an email with the shipment details and tracking number.
Note: Tracking information may take up to 24 hours to appear. Express delivery typically takes 3–5 business days.
5.How can I obtain technical support or documentation for STM32L452REY6TR?
For technical support, including STM32L452REY6TR datasheets, pinout diagrams, or application guidance, please contact our engineering support team. They can provide detailed documentation and assistance for your STM32L452REY6TR requirements.
6.How does Aetrix verify that STM32L452REY6TR is sourced from the original manufacturer or authorized distributors?
All STM32L452REY6TR products on Aetrix are procured from qualified distributors and authorized channels. Our dedicated quality assurance team conducts strict verification, including traceability checks and, if necessary, third-party testing. This ensures that STM32L452REY6TR meets industry standards.
7.What is the process for return or replacement of STM32L452REY6TR?
All STM32L452REY6TR units undergo pre-shipment inspection (PSI). If there is an issue with STM32L452REY6TR, returns or replacements are accepted under the following conditions:
1.Quantity discrepancies, incorrect items, or visible external defects (such as breakage or corrosion), acknowledged by Aetrix.
2.The issue is reported within 90 days of delivery.
3.The STM32L452REY6TR part is unused and in its original packaging.
Return procedure for STM32L452REY6TR:
1.Submit a request within 90 days.
2.Obtain a Return Material Authorization (RMA) from Aetrix.
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