STMicroelectronics STM32L452VCI6
- Part No.:
- STM32L452VCI6
- Manufacturer:
- STMicroelectronics
- Category:
- Microcontrollers
- Package:
- 100-UFBGA
- Datasheet:
-
STM32L452VCI6.pdf
- Description:
- IC MCU 32BIT 256KB FLSH 100UFBGA
- Quantity:
- Payment:

- Shipping:

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Product details
Overview
STM32L452VCI6 from STMicroelectronics is an ultra-low-power Arm® Cortex®-M4 32-bit MCU with FPU, 80 MHz max frequency, 512 KB Flash, 160 KB SRAM, and integrated analog peripherals including 12-bit ADC (5 Msps), dual 12-bit DAC, op-amp with PGA, and RTC with hardware calendar. It supports external SMPS for 36 µA/MHz run efficiency and operates from -40 °C to 125 °C in LQFP100 package - deployed in battery-powered industrial sensors and portable medical monitors.
For engineers reviewing the STM32L452VCI6 datasheet, STM32L452VCI6 pinout, STM32L452VCI6 application, or STM32L452VCI6 equivalent, key selection criteria include verified ultra-low-power modes (22 nA shutdown, 375 nA standby with RTC), dual-voltage domain analog subsystem (independent VDDA supply), and full USB 2.0 FS crystal-less operation with LPM/BCD support.
Technical Context
The STM32L452VCI6 implements an Adaptive Real-time Accelerator (ART Accelerator™) enabling zero-wait-state execution from Flash at 80 MHz, paired with a Memory Protection Unit (MPU) and interconnect matrix for deterministic peripheral arbitration. Its power architecture integrates dual regulators (LDO + optional external SMPS), brown-out reset (BOR), and FlexPowerControl supporting seven low-power modes including Stop 2 with 4 µs wakeup and Batch Acquisition Mode (BAM) for sensor data bursts.
Clock system includes dual PLLs (system/audio), auto-trimmed multispeed oscillator (±0.25%), 4–48 MHz HSE, 32 kHz LSE for RTC, and 48 MHz clock recovery for USB. Analog subsystem features independent VDDA supply, hardware oversampling up to 16-bit on ADC, and buffered 2.048 V/2.5 V reference voltage output.
Key Specifications
| Parameter | Value and Actual Design Meaning |
|---|---|
| Core | Arm Cortex-M4 with FPU, 80 MHz max, 100 DMIPS, DSP instructions, MPU |
| Memory | 512 KB Flash (single-bank, code readout protection), 160 KB SRAM (32 KB with parity) |
| Power Efficiency | 36 µA/MHz in SMPS mode @ 3.3 V; 22 nA shutdown; 375 nA standby with RTC |
| Analog Peripherals | 1× 12-bit ADC (5 Msps, 16-bit oversampling), 2× 12-bit DAC, 1× op-amp with PGA, 2× comparators |
| Communication | USB 2.0 FS crystal-less, 4× I²C FM+, 3× USART, 1× LPUART, 3× SPI, 1× SAI, CAN 2.0B, SDMMC |
| Timers & RTC | 12× timers including advanced TIM1, 2× low-power LPTIM, RTC with HW calendar & calibration |
| Package & Temp | LQFP100 (14×14 mm), -40 °C to +125 °C industrial grade, ECOPACK2® compliant |
Pinout & Package
LQFP100 package: 100-pin plastic quad flat pack, 0.5 mm pitch, exposed thermal pad, RoHS-compliant and ECOPACK2® certified. Pinout validated per DS11912 Rev 7 Section 4 (Pinouts and pin description) and Table 16 (STM32L452xx pin definitions).
| Pin/Terminal | Circuit Role | Design Meaning |
|---|---|---|
| VDD, VDDA, VSS, VSSA | Power supply and ground | Dual-domain supply: VDD/VSS for digital core & I/O; VDDA/VSSA for analog peripherals (ADC/DAC/OPAMP) - must be decoupled separately |
| PA0–PA15, PB0–PB15, PC0–PC15, PD0–PD15, PE0–PE7 | General-purpose I/O | Up to 83 fast I/Os; most 5 V-tolerant; support 16 alternate functions (AF0–AF15) including USB, CAN, SAI, SDMMC |
| OSC_IN / OSC_OUT | External high-speed oscillator input/output | Connects to 4–48 MHz crystal; enables precise clocking for USB, audio, and real-time applications |
| RTC_OUT / RTC_IN | RTC oscillator terminals | Supports 32.768 kHz crystal for autonomous RTC operation during VBAT mode (145 nA) |
| VBAT | Battery backup supply | Powers RTC and 32×32-bit backup registers during main power loss; enables tamper detection and calendar retention |
| NRST | Active-low reset input | Asynchronous reset with internal pull-up; accepts external push-button or supervisor IC assertion |
| SWCLK / SWDIO | Serial Wire Debug interface | 2-pin debug port supporting programming, real-time trace, and breakpoints without JTAG overhead |
Key Features
| Feature | Design Value |
|---|---|
| FlexPowerControl architecture | Seven configurable low-power modes with sub-µA quiescent current; Stop 2 retains SRAM and registers while disabling CPU and flash |
| ART Accelerator™ | Enables 0-wait-state execution from Flash at 80 MHz - eliminates cache misses in deterministic real-time control loops |
| Dual-voltage analog domain | VDDA-independent supply allows clean analog measurements even during digital switching noise or SMPS transients |
| Crystal-less USB 2.0 FS | Integrated clock recovery system (CRS) eliminates external USB crystal - reduces BOM cost and PCB area |
| Hardware security | Firewall, CRC unit, 96-bit unique ID, and readout protection (RDP) Level 1/2 prevent firmware cloning and unauthorized access |
Applications
| Portable ECG Monitor | Smart Gas Sensor Node |
|---|---|
Use Scenario: Wearable device acquiring biopotential signals with real-time QRS detection and Bluetooth LE telemetry. IC Role / Device Role / Timing Role: Main controller executing signal processing (FIR filtering, peak detection) and managing dual ADC channels with hardware oversampling. Use Value: 12-bit ADC at 5 Msps with 16-bit effective resolution enables accurate ECG waveform capture; 375 nA standby with RTC maintains time-synchronized sampling intervals between transmissions. | Use Scenario: Battery-operated IoT node detecting CO, NO₂, and VOCs using electrochemical and MOS sensors with temperature compensation. IC Role / Device Role / Timing Role: Sensor hub aggregating analog inputs, performing calibration via internal temperature sensor and VREFINT, and scheduling low-duty-cycle radio wakeups. Use Value: Dual 12-bit DAC drives sensor bias voltages; op-amp with PGA conditions weak sensor outputs; 22 nA shutdown extends 10-year battery life in intermittent-read deployments. |
| Industrial PLC I/O Module | USB-Powered Audio Interface |
Use Scenario: DIN-rail mounted module converting 4–20 mA field signals to Modbus RTU over RS-485 with local diagnostics. IC Role / Device Role / Timing Role: Real-time I/O processor handling analog input conditioning, isolation supervision, and deterministic UART timing for protocol compliance. Use Value: Advanced TIM1 supports precise PWM generation for LED status indicators; 83 GPIOs with 5 V tolerance interface directly to legacy industrial logic levels. | Use Scenario: Bus-powered USB audio adapter supporting stereo playback/recording with headphone amp and mic preamp. IC Role / Device Role / Timing Role: Audio SoC managing SAI-to-USB bridging, sample rate conversion, and low-latency DAC/ADC buffering. Use Value: SAI interface supports I²S/PCM with master/slave modes; crystal-less USB ensures plug-and-play compatibility; 160 KB SRAM buffers multiple audio frames for jitter-free streaming. |
Equivalent & Alternatives
The following parts are listed as comparable options for similar ultra-low-power MCU applications.
| Alternative Part | Technical Difference | Application Difference | Selection Advice |
|---|---|---|---|
| STM32L476VGT6 | Higher Flash (1 MB) and SRAM (128 KB), added Chrom-ART accelerator, no SAI, same LQFP100 package | Targeted at GUI-rich HMI applications; lacks audio interface required for SAI-dependent designs | Select when display rendering or larger firmware image size is critical; avoid if SAI or crystal-less USB is mandatory |
| STM32L552VET6 | ARMv8-M TrustZone®, 512 KB Flash, 256 KB SRAM, enhanced crypto (AES-256, PKA), 110 µA/MHz run mode | Designed for secure boot, firmware updates, and data encryption in regulated environments (e.g., medical, payment) | Choose for applications requiring hardware-enforced security boundaries; higher power consumption offsets ultra-low-power advantage of L452 |
Compared with STM32L476VGT6, the STM32L452VCI6 offers superior audio integration and lower active power, while the STM32L552VET6 trades raw efficiency for cryptographic isolation - making the L452 optimal for cost-sensitive, battery-constrained audio/sensing nodes where TrustZone is unnecessary.
Availability
STM32L452VCI6 is available at Aetrix Electronics and suitable for portable medical devices, industrial wireless sensors, USB-powered audio interfaces, and smart metering systems requiring stable component supply across multi-year production cycles.
Supply support for STM32L452VCI6 includes scheduled delivery planning, volume procurement assistance, BOM continuity management, traceable sourcing, and lifecycle availability coordination for OEM customers, industrial embedded developers, connected-device designers, and electronics production programs.
Manufacturer
STMicroelectronics is a global semiconductor leader headquartered in Geneva, Switzerland, designing and manufacturing microcontrollers, power management ICs, sensors, and analog components for industrial, automotive, and consumer markets.
The STM32L4 series targets ultra-low-power embedded applications demanding extended battery life, rich analog integration, and real-time performance - optimized for energy harvesting, wearables, and edge intelligence nodes.
FAQ
What is the maximum operating temperature rating for STM32L452VCI6?
The STM32L452VCI6 is qualified for industrial operation from -40 °C to +125 °C ambient temperature, verified per JEDEC JESD47 stress testing and documented in Section 6.3.1 of DS11912 Rev 7. This extended range supports deployment in enclosed enclosures, motor control cabinets, and outdoor environmental monitoring housings without derating.
Does STM32L452VCI6 support external SMPS control, and how is it implemented?
Yes - the STM32L452VCI6 supports external SMPS via dedicated VDD12 and VDD12_IO pins, enabling dynamic voltage scaling down to 1.10 V. When enabled, SMPS mode reduces active current to 36 µA/MHz (vs. 84 µA/MHz in LDO mode), with automatic transition managed by the PWR_CR4 register's VOS bits and hardware-controlled enable/disable sequencing.
Can the internal op-amp in STM32L452VCI6 drive a 50 Ω load directly?
No - the integrated op-amp is specified for rail-to-rail output swing with ±20 mA short-circuit current, but its output stage is not designed for continuous 50 Ω loads. Driving such impedances requires external buffer amplification; ST recommends using the op-amp for sensor signal conditioning (e.g., PGA gain stages into ADC) rather than direct line driving.
Is the USB interface on STM32L452VCI6 fully compliant with USB Battery Charging v1.2 (BC1.2)?
Yes - the USB 2.0 full-speed interface implements BC1.2 detection logic per the datasheet (Section 3.32), supporting D+ and D− line enumeration for Dedicated Charging Ports (DCP), Charging Downstream Ports (CDP), and Standard Downstream Ports (SDP). Hardware BCD circuitry eliminates need for external charging ICs in portable designs.
STM32L452VCI6 Specifications
- Product attributes
- Attribute value
- Manufacturer:
- STMicroelectronics
- Package/Case:
- 100-UFBGA
- Series:
- STM32L4
- Packaging:
- Tray
- Product Status:
- Active
- Programmable:
- Not Verified
- Core Processor:
- ARM® Cortex®-M4
- Core Size:
- 32-Bit Single-Core
- Speed:
- 80MHz
- Connectivity:
- CANbus, I2C, IrDA, LINbus, MMC/SD, QSPI, SAI, SPI, UART/USART, USB
- Peripherals:
- Brown-out Detect/Reset, DMA, PWM, WDT
- Number of I/O:
- 83
- Program Memory Size:
- 256KB (256K x 8)
- Program Memory Type:
- FLASH
- EEPROM Size:
- -
- RAM Size:
- 160K x 8
- Voltage - Supply (Vcc/Vdd):
- 1.71V ~ 3.6V
- Data Converters:
- A/D 16x12b; D/A 1x12b
- Oscillator Type:
- Internal
- Operating Temperature:
- -40°C ~ 85°C (TA)
- Grade:
- -
- Qualification:
- -
- Mounting Type:
- Surface Mount
- Supplier Device Package:
STM32L452VCI6 FAQ
1.How can I place an order for STM32L452VCI6 through Aetrix?
Please submit a Request for Quotation (RFQ) for STM32L452VCI6 on Aetrix. Our sales agent will provide a competitive quotation and guide you through the order confirmation once you accept the terms.
2.Are the price and stock information for STM32L452VCI6 reliable?
The price and inventory of STM32L452VCI6 are updated periodically and may fluctuate due to market conditions. Stock and pricing data are typically refreshed every 24 hours. Quotation validity for STM32L452VCI6 is usually 5 days.
3.What payment methods are accepted for STM32L452VCI6?
We accept Wire Transfer, PayPal, Credit Card, Western Union, MoneyGram, and Escrow for STM32L452VCI6 transactions.
Note: Certain payment methods may incur a processing fee.
4.How is shipping managed for STM32L452VCI6?
STM32L452VCI6 orders can be shipped via leading logistics carriers, including DHL, UPS, FedEx, TNT, or Registered Mail.
Once your STM32L452VCI6 order is processed, you will receive an email with the shipment details and tracking number.
Note: Tracking information may take up to 24 hours to appear. Express delivery typically takes 3–5 business days.
5.How can I obtain technical support or documentation for STM32L452VCI6?
For technical support, including STM32L452VCI6 datasheets, pinout diagrams, or application guidance, please contact our engineering support team. They can provide detailed documentation and assistance for your STM32L452VCI6 requirements.
6.How does Aetrix verify that STM32L452VCI6 is sourced from the original manufacturer or authorized distributors?
All STM32L452VCI6 products on Aetrix are procured from qualified distributors and authorized channels. Our dedicated quality assurance team conducts strict verification, including traceability checks and, if necessary, third-party testing. This ensures that STM32L452VCI6 meets industry standards.
7.What is the process for return or replacement of STM32L452VCI6?
All STM32L452VCI6 units undergo pre-shipment inspection (PSI). If there is an issue with STM32L452VCI6, returns or replacements are accepted under the following conditions:
1.Quantity discrepancies, incorrect items, or visible external defects (such as breakage or corrosion), acknowledged by Aetrix.
2.The issue is reported within 90 days of delivery.
3.The STM32L452VCI6 part is unused and in its original packaging.
Return procedure for STM32L452VCI6:
1.Submit a request within 90 days.
2.Obtain a Return Material Authorization (RMA) from Aetrix.
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