STMicroelectronics STM32L452VEI6
- Part No.:
- STM32L452VEI6
- Manufacturer:
- STMicroelectronics
- Category:
- Microcontrollers
- Package:
- 100-UFBGA
- Datasheet:
-
STM32L452VEI6.pdf
- Description:
- IC MCU 32BIT 512KB FLSH 100UFBGA
- Quantity:
- Payment:

- Shipping:

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Product details
Overview
STM32L452VEI6 from STMicroelectronics is an ultra-low-power Arm® Cortex®-M4 32-bit MCU with FPU, 80 MHz max frequency, 512 KB Flash, 160 KB SRAM, and integrated analog peripherals including 12-bit ADC (5 Msps), dual 12-bit DAC, op-amp with PGA, and RTC with hardware calendar. It targets battery-powered industrial sensors, portable medical devices, and smart metering systems requiring sub-µA standby operation and robust mixed-signal capability.
For engineers reviewing the STM32L452VEI6 datasheet, STM32L452VEI6 pinout, STM32L452VEI6 application, or STM32L452VEI6 equivalent, key selection criteria include verified 375 nA Standby+RTC current, SMPS-compatible 36 µA/MHz run mode, 83 GPIOs (most 5 V-tolerant), and full USB 2.0 FS crystal-less support - all confirmed in DS11912 Rev 7.
Technical Context
This MCU implements the Adaptive Real-time Accelerator (ART Accelerator™) enabling zero-wait-state execution from Flash at 80 MHz, paired with a memory protection unit (MPU) and interconnect matrix for deterministic peripheral arbitration. Its power architecture integrates dual voltage regulators (LDO/SMPS), brown-out reset (BOR), and five low-power modes - including Stop 2 with 4 µs wakeup and VBAT mode at 145 nA - validated across -40 °C to 125 °C.
The analog subsystem features independent supply domains, a 12-bit ADC with hardware oversampling up to 16-bit effective resolution, two ultra-low-power comparators, and a buffered 2.048 V/2.5 V reference - all specified with 200 µA/Msps ADC power efficiency and ±1% internal 16 MHz RC accuracy.
Key Specifications
| Parameter | Value and Actual Design Meaning |
|---|---|
| Core | Arm Cortex-M4 with FPU, 80 MHz max, 100 DMIPS, ART Accelerator for 0-wait-state Flash execution |
| Memory | 512 KB Flash (single-bank, code readout protection), 160 KB SRAM (32 KB with hardware parity) |
| Power Consumption | 375 nA Standby + RTC; 2.40 µA Stop 2 + RTC; 36 µA/MHz run mode with external SMPS |
| Analog Peripherals | 1× 12-bit ADC (5 Msps, 16-bit oversampled), 2× 12-bit DAC, 1× op-amp with PGA, 2× comparators, 2.048 V/2.5 V VREFBUF |
| Timers & Connectivity | 12 timers (including advanced TIM1, LPTIM1/2), USB 2.0 FS crystal-less, SAI, 4× I²C FM+, 3× USART, CAN 2.0B, SDMMC, QUADSPI |
| Package & I/O | UFBGA100 (7×7 mm), 83 fast I/Os (most 5 V-tolerant), ECOPACK2® compliant |
Pinout & Package
STM32L452VEI6 is housed in a 100-pin Ultra-Fine-Pitch Ball Grid Array (UFBGA100) package with 0.5 mm pitch and 7 mm × 7 mm body size, optimized for space-constrained portable designs. Pin functions are defined per DS11912 Rev 7 Section 4 (Pinouts and pin description), with dedicated VDD/VSS pairs, multiple VREF+/VREF– inputs, and configurable alternate function mapping across AF0–AF15.
| Pin/Terminal | Circuit Role | Design Meaning |
|---|---|---|
| VDD, VDDA, VDDIO2 | Main, analog, and I/O power supplies | Independent domains enable precise analog performance and 5 V-tolerant I/O operation without level shifters |
| VSS, VSSA, VSSIO2 | Ground references | Dedicated analog ground (VSSA) minimizes noise coupling into ADC/DAC paths |
| PA0–PA15, PB0–PB15, etc. | General-purpose I/Os | 83 pins support multiple alternate functions (UART, SPI, I²C, CAN, SAI); most tolerate 5 V input |
| PC13–PC15 | RTC oscillator inputs | Support 32.768 kHz crystal connection for hardware calendar and alarm functionality |
| VBAT | Battery backup supply | Enables RTC and 32×32-bit backup registers during main power loss (145 nA quiescent) |
Key Features
| Feature | Design Value |
|---|---|
| FlexPowerControl architecture | Five low-power modes with validated currents: 22 nA Shutdown, 106 nA Standby, 375 nA Standby+RTC, 2.40 µA Stop 2+RTC |
| ART Accelerator™ | Enables 0-wait-state execution from Flash at 80 MHz, eliminating cache misses in deterministic real-time loops |
| Integrated analog subsystem | Single-chip solution with ADC (5 Msps), dual DAC, op-amp+PGA, and buffered reference - no external precision components needed |
| USB 2.0 Full-Speed crystal-less | Eliminates external 48 MHz crystal and associated capacitors, reducing BOM cost and PCB area for portable endpoints |
| ECOPACK2® compliance | Meets RoHS, halogen-free, and strict environmental requirements for industrial and medical deployments |
Applications
| Industrial Sensor Node | Portable ECG Monitor |
|---|---|
Use Scenario: Wireless temperature/humidity/pressure node operating on coin-cell battery for 5+ years. IC Role / Device Role / Timing Role: Main controller executing sensor fusion, BLE stack, and ultra-low-power scheduling via LPTIM2 wakeups. Use Value: 375 nA Standby+RTC and 4 µs Stop 2 wakeup minimize active time; integrated ADC and op-amp condition analog sensor signals without external signal chain. |
Use Scenario: Battery-powered handheld ECG device acquiring 3-lead biopotential signals with clinical-grade SNR. IC Role / Device Role / Timing Role: Signal acquisition engine using 12-bit ADC oversampling (16-bit effective), real-time filtering on Cortex-M4+FPU, and USB FS data streaming. Use Value: Hardware oversampling and 200 µA/Msps ADC efficiency extend battery life; built-in op-amp with PGA replaces discrete instrumentation amplifier stage. |
| Smart Gas Meter | Asset Tracking Beacon |
Use Scenario: UL-certified gas meter with pulse counting, pressure compensation, and LoRaWAN backhaul. IC Role / Device Role / Timing Role: Primary MCU managing metrology algorithms, RTC-based billing cycles, and secure firmware updates via embedded Flash protection. Use Value: 512 KB Flash supports dual-bank OTA updates; hardware CRC and 96-bit UID ensure secure boot and device identity; CAN 2.0B interfaces to external valve controllers. |
Use Scenario: GPS-enabled logistics tag reporting location every 6 hours using Li-SOCl₂ primary cell. IC Role / Device Role / Timing Role: Power manager coordinating GPS cold start, cellular modem burst transmission, and deep sleep via VBAT-backed RTC alarms. Use Value: 145 nA VBAT mode sustains RTC/calendar during 10-year shelf life; SMPS-compatible 36 µA/MHz run mode maximizes energy per transmit cycle. |
Equivalent & Alternatives
The following parts are listed as comparable options for similar ultra-low-power MCU applications.
| Alternative Part | Technical Difference | Application Difference | Selection Advice |
|---|---|---|---|
| STM32L476RG | Higher Flash (1 MB), larger SRAM (128 KB), includes TFT-LCD controller and Ethernet MAC - no SMPS support | Better suited for HMI or wired industrial gateways; lacks 36 µA/MHz SMPS efficiency and VBAT-optimized shutdown | Select when display interface or Ethernet is required; avoid if sub-µA standby or SMPS integration is critical |
| STM32L552RE | ARM TrustZone®, 110 µA/MHz run (LDO), 420 nA Standby+RTC, 512 KB Flash, same UFBGA100 footprint | Designed for secure firmware execution (AES-256, PKA); higher leakage invalidates ultra-low-power sensor use cases | Choose only when cryptographic isolation is mandatory; not drop-in for power-critical legacy designs |
Compared with STM32L452VEI6, STM32L476RG trades ultra-low-power optimization for richer peripherals and memory, while STM32L552RE adds security at the cost of 12% higher standby current - making STM32L452VEI6 optimal for battery life–constrained edge nodes where trust anchors are handled externally.
Availability
STM32L452VEI6 is available at Aetrix Electronics and suitable for industrial sensor nodes, portable medical monitors, smart utility meters, and asset tracking beacons requiring stable component supply across extended product lifecycles.
Supply support for STM32L452VEI6 includes scheduled delivery planning, volume procurement assistance, BOM continuity management, traceable sourcing, and lifecycle availability coordination for OEM customers, industrial embedded developers, connected-device designers, and electronics production programs.
Manufacturer
STMicroelectronics is a global semiconductor leader headquartered in Geneva, Switzerland, designing and manufacturing microcontrollers, power management ICs, sensors, and automotive semiconductors.
The STM32L4 series targets ultra-low-power embedded applications demanding high performance-per-milliwatt, with STM32L452VEI6 specifically engineered for battery-operated devices needing rich analog integration and long-term RTC reliability.
FAQ
What is the minimum supply voltage for STM32L452VEI6 in Run mode?
The absolute minimum supply voltage is 1.71 V, validated across the full -40 °C to 125 °C operating range. At 1.71 V, core frequency is limited to 24 MHz per DS11912 Rev 7 Table 23; full 80 MHz operation requires ≥1.76 V. The device includes programmable brown-out reset (BOR) thresholds at 1.62 V, 1.8 V, 2.1 V, and 2.4 V.
Does STM32L452VEI6 support external SMPS control, and how is it implemented?
Yes - it supports external SMPS via the VDD12 pin and dedicated control logic. When enabled, the internal regulator bypasses LDO operation, allowing direct connection to an external 1.1 V SMPS output. This reduces active-mode current to 36 µA/MHz (vs. 84 µA/MHz in LDO mode), as measured with code running from Flash and ART Accelerator enabled (DS11912 Rev 7 Table 28).
How many ADC channels does STM32L452VEI6 support, and what is its maximum sampling rate?
It integrates one 12-bit ADC with up to 16 external input channels (plus internal temp sensor and VREFINT). Maximum sampling rate is 5 Msps in single-ended mode with synchronous clocking, achieving 200 µA/Msps efficiency. Hardware oversampling can extend effective resolution to 16 bits at reduced rates (e.g., 12-bit @ 5 Msps → 16-bit @ 312.5 ksps).
Is STM32L452VEI6 pin-compatible with other STM32L4xx variants in UFBGA100?
No - while STM32L452VEI6 shares the UFBGA100 mechanical footprint with STM32L476RG and STM32L496VG, pin functions differ significantly. For example, PA11/PA12 are USB D+/D− on L452 but ETH_REF_CLK/ETH_MDC on L476. Migration requires full schematic and layout revision per DS11912 Rev 7 pin definition tables.
STM32L452VEI6 Specifications
- Product attributes
- Attribute value
- Manufacturer:
- STMicroelectronics
- Package/Case:
- 100-UFBGA
- Series:
- STM32L4
- Packaging:
- Tray
- Product Status:
- Active
- Programmable:
- Not Verified
- Core Processor:
- ARM® Cortex®-M4
- Core Size:
- 32-Bit Single-Core
- Speed:
- 80MHz
- Connectivity:
- CANbus, I2C, IrDA, LINbus, MMC/SD, QSPI, SAI, SPI, UART/USART, USB
- Peripherals:
- Brown-out Detect/Reset, DMA, PWM, WDT
- Number of I/O:
- 83
- Program Memory Size:
- 512KB (512K x 8)
- Program Memory Type:
- FLASH
- EEPROM Size:
- -
- RAM Size:
- 160K x 8
- Voltage - Supply (Vcc/Vdd):
- 1.71V ~ 3.6V
- Data Converters:
- A/D 16x12b; D/A 1x12b
- Oscillator Type:
- Internal
- Operating Temperature:
- -40°C ~ 85°C (TA)
- Grade:
- -
- Qualification:
- -
- Mounting Type:
- Surface Mount
- Supplier Device Package:
STM32L452VEI6 FAQ
1.How can I place an order for STM32L452VEI6 through Aetrix?
Please submit a Request for Quotation (RFQ) for STM32L452VEI6 on Aetrix. Our sales agent will provide a competitive quotation and guide you through the order confirmation once you accept the terms.
2.Are the price and stock information for STM32L452VEI6 reliable?
The price and inventory of STM32L452VEI6 are updated periodically and may fluctuate due to market conditions. Stock and pricing data are typically refreshed every 24 hours. Quotation validity for STM32L452VEI6 is usually 5 days.
3.What payment methods are accepted for STM32L452VEI6?
We accept Wire Transfer, PayPal, Credit Card, Western Union, MoneyGram, and Escrow for STM32L452VEI6 transactions.
Note: Certain payment methods may incur a processing fee.
4.How is shipping managed for STM32L452VEI6?
STM32L452VEI6 orders can be shipped via leading logistics carriers, including DHL, UPS, FedEx, TNT, or Registered Mail.
Once your STM32L452VEI6 order is processed, you will receive an email with the shipment details and tracking number.
Note: Tracking information may take up to 24 hours to appear. Express delivery typically takes 3–5 business days.
5.How can I obtain technical support or documentation for STM32L452VEI6?
For technical support, including STM32L452VEI6 datasheets, pinout diagrams, or application guidance, please contact our engineering support team. They can provide detailed documentation and assistance for your STM32L452VEI6 requirements.
6.How does Aetrix verify that STM32L452VEI6 is sourced from the original manufacturer or authorized distributors?
All STM32L452VEI6 products on Aetrix are procured from qualified distributors and authorized channels. Our dedicated quality assurance team conducts strict verification, including traceability checks and, if necessary, third-party testing. This ensures that STM32L452VEI6 meets industry standards.
7.What is the process for return or replacement of STM32L452VEI6?
All STM32L452VEI6 units undergo pre-shipment inspection (PSI). If there is an issue with STM32L452VEI6, returns or replacements are accepted under the following conditions:
1.Quantity discrepancies, incorrect items, or visible external defects (such as breakage or corrosion), acknowledged by Aetrix.
2.The issue is reported within 90 days of delivery.
3.The STM32L452VEI6 part is unused and in its original packaging.
Return procedure for STM32L452VEI6:
1.Submit a request within 90 days.
2.Obtain a Return Material Authorization (RMA) from Aetrix.
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